Glucagon antibody

Principal name

Glucagon antibody

Alternative names for Glucagon antibody

GCG

SwissProt ID

P01272 (Bovin), P01274 (Pig), P01275 (Human), P05110 (Cavpo), P06883 (Rat), P29794 (Canfa), P55095 (Mouse), P68259 (Chick), P68274 (Rabit), Q8MJ25 (Sheep)

Gene ID

2641 (GCG), 280802, 397595, 24952 (Gcg), 1226415 (Q98IH6)

Available reactivities

Hu (Human), Can (Canine), Fe (Feline), GP (Guinea Pig), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Mam (Mammalia), Bov (Bovine), Chk (Chicken), African clawed frog, Mky (Monkey), Sh (Sheep)

Available hosts

Mouse, Rabbit, Sheep, Guinea Pig, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C), Radioimmunoassay (R), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Dot blot (Dot), ELISA (detection) (E(detection)), Flow Cytometry (F), Immunoprecipitation (IP)

Background of Glucagon antibody

Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. GLP-1 is a potent stimulator of glucose-dependent insulin release. Play important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Have growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability. Oxyntomodulin significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness. Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life.

General readings

Meier,J.J., (2006) Gastroenterology 130 (1), 44-54

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GLP1 antibody

GLP1 Mouse IgG1 ID/GLP-1/18 Purified Hu ICC/IF, P
10 µg / €270.00
  Acris Antibodies GmbH

GLP1 antibody

GLP1 Mouse IgG1 GLP-1/18 Purified Hu, Por, Rt Dot, ICC/IF, P
0.1 mg / €690.00
  Acris Antibodies GmbH

GLP1 antibody

GLP1 Mouse IgG1 GLP-1/18 Purified Hu, Por, Rt Dot, ICC/IF, P
10 µg / €170.00
  Acris Antibodies GmbH

GLP1 antibody

Figure 1. Immunofluorescence of Human Distal Ileum Tissue. Antigen retrieval was done with Tris-EDTA, pH9.0 in pressure cooker for 20 minutes. Optimum staining of L-type cells secreting GLP1 was observed. Mouse IgG1 HGL-B5 Aff - Purified Hu E, ICC/IF
0.1 mg / €390.00
  Acris Antibodies GmbH

GLP1 antibody

GLP1 Mouse IgG2a Purified Hu E, WB
0.1 mg / €480.00
  Novus Biologicals Inc.

GLP1 antibody

GLP1 Mouse IgG1 Purified Hu E, WB
0.1 mg / €480.00
  Novus Biologicals Inc.

GLP1 antibody

GLP1 Mouse IgG1 Purified E, WB
0.1 mg / €480.00
  Novus Biologicals Inc.

Glucagon antibody

Human pancreas stained with Anti-Glucagon antibody (AP15578PU) Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

Glucagon antibody

Human pancreas stained with Anti-Glucagon antibody (AP15578PU) Rabbit Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

Glucagon antibody

Human pancreas stained with Anti-Glucagon antibody (AP15578PU) Rabbit Purified Hu P

Regular Price: 0.1 ml / €190.00

Special Price: 0.1 ml / €105.00

  Acris Antibodies GmbH

Glucagon antibody

Western blot analysis of extracts from COS7 cells, using Glucagon antibody (#TA313127).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glucagon antibody

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human lung and colon cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA323064 (GCG (GLP1) Antibody) at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA323064 (GCG (GLP1) Antibody) at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glucagon antibody

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human brain tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using GCG (GLP1) antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glucagon antibody

Predicted cell location: Cytoplasm. Positive control: Human breast cancer tissue. Recommended dilution: 1/10-50  The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using GCG antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glucagon (C-term) antibody

Western blot analysis of Glucagon Antibody (C-term) (Cat. #TA324867) in Jurkat cell line lysates (35ug/lane). GCG (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Glucagon antibody

Immunohistochemistry staining of Paraffin Pancreas tissue by Glucagon antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic) Rabbit Purified Hu P
1 ml / €290.00
  OriGene Technologies, Inc.

Glucagon antibody

Western blot analysis on COS7 cell lysate using Glucagon Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glucagon antibody

Western blot analysis using GCG antibody Cat.-No AM06563SU-N against HEK293 (1) and GCG (AA: 1-180)-hIgGFc transfected HEK293 (2) cell lysate. Mouse IgG1 2F9 Ascites Hu E, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

Glucagon antibody

Glucagon Mouse IgG1 IMD-7 Purified Hu, Rt IP, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Glucagon antibody

Human Pancreas Paraffin Section stained with anti-Glucagon Antibody Cat.-No AM33202SU (Clone BS71). Mouse IgG1 BS71 Ascites Hu P
1 ml / €900.00
  Acris Antibodies GmbH

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