Glucagon receptor antibody

Principal name

Glucagon receptor antibody

Alternative names for Glucagon receptor antibody

GCGR, GL-R

SwissProt ID

P30082 (Rat), P47871 (Human), Q61606 (Mouse)

Gene ID

2642 (GCGR)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Hst (Hamster), Mky (Monkey)

Available hosts

Rabbit, Goat

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Dot blot (Dot), Flow Cytometry (F)

Background of Glucagon receptor antibody

The Glucagon Receptor mediates the effects of glucagon in controlling glucose metabolism by initiating a cascade of events that regulate the amount of glucose released from the liver into the bloodstream. Glucagon generally functions as a counterregulatory hormone, opposing the actions of insulin, in maintaining the levels of blood glucose, particularly in patients with hypoglycemia. In patients with diabetes, excess glucagon secretion plays a primary role in the metabolic perturbations associated with diabetes, such as hyperglycemia. Glucagon knockout mice exhibit reduced glood glucose levels, improved glucose tolerance, elevated blood glucagon levels, and normal insulin levels. Despite a total absence of glucagon receptors, these animals maintained near-normal glycemia and normal lipidemia, in the presence of circulating glucagon concentrations that were elevated by two orders of magnitude. A missense mutation (Gly40Ser) in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus.
The glucagon receptor has been reported to be expressed in liver and adipose, but not in adrenal medulla. ESTs have been isolated from liver/spleen and kidney libraries.

General readings

1. Komurov K  et al. The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells. Mol Syst Biol 8:596 (2012). WB ; Human .

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glucagon receptor antibody

Western blot (WB) analysis of Glucagon Receptor antibody (Cat.-No. AP01269PU-N) at 1/500 dilution Lane 1: HEK293T whole cell lysate Lane 2: Raw264.7 whole cell lysate Lane 3: H9C2 whole cell lysate. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Glucagon receptor antibody

Human, Adipocyte: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Bov, Can, Eq, Hst, Hu, Mky
50 µg / €379.00
  OriGene Technologies, Inc.

Glucagon receptor antibody

Western blot analysis of extracts from COLO205 cells, using GLR antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glucagon receptor antibody

Anti-Glucagon Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €379.00
  OriGene Technologies, Inc.

Glucagon receptor (N-term) antibody

Anti-Glucagon Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

Glucagon receptor (C-term) antibody

Anti-Glucagon Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

Glucagon receptor (N-term) antibody

Anti-Glucagon Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

Glucagon receptor antibody

Anti-GCGR / Glucagon Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu, Ms, Rt
50 µg / €379.00
  OriGene Technologies, Inc.

Glucagon receptor (Extracell. Dom.) antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

Glucagon receptor antibody

Glucagon receptor Goat Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

Glucagon receptor antibody

Immunofluorescence analysis of HeLa cells, using GLR Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

Glucagon receptor antibody

Immunofluorescence analysis of HeLa cells, using GLR Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

Glucagon receptor antibody

Immunohistochemical analysis of Glucagon Receptor staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Glucagon receptor antibody

Immunohistochemical analysis of Glucagon Receptor staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Glucagon receptor antibody

Immunohistochemical analysis of Glucagon Receptor staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Glucagon receptor antibody

Immunohistochemistry: Glucagon Receptor Antibody [19650002] - IHC using anti GCGR SEQer antibody Rabbit Hu E, P
50 µg / €440.00
  Novus Biologicals Inc.

Glucagon receptor antibody

ELISA: Glucagon Receptor Antibody [19660002] - Affinity Purified Rabbit Hu E, WB
50 µg / €440.00
  Novus Biologicals Inc.

Glucagon receptor antibody

Glucagon receptor Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Glucagon receptor antibody

Western Blot: Glucagon Receptor Antibody [NBP1-30971] - Western blot analysis of Glucagon Receptor on 293T, diluted at 1:1000 with 10% SDS PAGE gel. Rabbit IgG Hu Dot, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Glucagon receptor antibody

Immunohistochemistry: Glucagon Receptor Antibody [NLS838] - Liver Rabbit Aff - Purified Hu P
50 µl / €440.00
  Novus Biologicals Inc.

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