Glucosidase 2 subunit beta antibody

Principal name

Glucosidase 2 subunit beta antibody

Alternative names for Glucosidase 2 subunit beta antibody

Glucosidase II beta, PRKCSH, G19P1, 80K-H protein, Protein kinase C substrate 60.1 kDa protein heavy chain

SwissProt ID

O08795 (Mouse), P14314 (Human), Q28034 (Bovin)

Gene ID

5589 (PRKCSH), 19089 (Prkcsh)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair), Immunoprecipitation (IP)

Background of Glucosidase 2 subunit beta antibody

Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum (ER). Glucosidase II is an ER-localized enzyme that contains alpha and beta subunits (Glucosidase IIalpha and Glucosidase IIbeta). The alpha and beta subunits form a defined heterodimeric complex with a molecular weight about 161 kDa. Glucosidase IIalpha is the catalyitc core of the enzyme and can function independently of the beta subunit. The sequence of Glucosidase IIbeta encodes protein rich in glutamic and aspartic acid with a putative ER retention signal (HDEL) at the C terminus. The phosphorylated form of Glucosidase IIbeta is localized in the plasma membrane and is highly expressed in FGF stimulated fibroblasts and epidermal carcinoma cells. Glucosidase IIbeta was first purified from a human carcinoma cell line as a potential substrate for protein kinase C. Through the HDEL signal at the C-terminus, Glucosidase IIbeta retains the complete complex in the ER.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glucosidase 2 subunit beta antibody

  Rabbit polyclonal antibody to PRKCSH (protein kinase C substrate 80K-H)  
Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. TA307924 diluted at 1:10000. Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glucosidase 2 subunit beta antibody

  Rabbit polyclonal anti-GLU2B antibody  
Western blot analysis of extracts from mouse brain cells, using GLU2B antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glucosidase 2 subunit beta antibody

Western blot (WB) analysis of Glucosidase II beta antibody (Cat.-No.: AP01229PU-N) in extracts from mouse brain. Rabbit Aff - Purified Hu, Ms ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Glucosidase 2 subunit beta antibody

Immunofluorescence analysis of HeLa cells, using GLU2B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

Glucosidase 2 subunit beta antibody

Immunofluorescence analysis of HeLa cells, using GLU2B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

PRKCSH - human gene knockout kit via CRISPR

PRKCSH - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PRKCSH - human gene knockout kit via CRISPR

PRKCSH - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRKCSH - human gene knockout kit via CRISPR

PRKCSH - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRKCSH - human gene knockout kit via CRISPR

PRKCSH - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Prkcsh - mouse gene knockout kit via CRISPR

Prkcsh - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Prkcsh - mouse gene knockout kit via CRISPR

Prkcsh - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Prkcsh - mouse gene knockout kit via CRISPR

Prkcsh - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Prkcsh - mouse gene knockout kit via CRISPR

Prkcsh - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PRKCSH overexpression lysate

PRKCSH overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

14 Item(s)

per page
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