Glutamate receptor 1 / GLUR1 antibody

Principal name

Glutamate receptor 1 / GLUR1 antibody

Alternative names for Glutamate receptor 1 / GLUR1 antibody

GluR-1, GRIA1, GLUH1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA1, AMPA-selective glutamate receptor 1

SwissProt ID

P19490 (Rat), P23818 (Mouse), P42261 (Human)

Gene ID

50592 (Gria1), 2890 (GRIA1), 14799

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Chk (Chicken), Mky (Monkey), Hst (Hamster), Bov (Bovine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP), Dot blot (Dot)

Background of Glutamate receptor 1 / GLUR1 antibody

AMPA receptors are members of the glutamate receptor family of ion channels that also include the NMDA and Kaite receptors. The three subfamilies are med after the origil synthetic agonists that were identified as selective ligands of each family. The α-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (AMPA) receptor subfamily includes four members AMPA1-AMPA4 that are also known as GluR1-GluR4 respectively. The functiol AMPA channel is believed to be a tetramer, with most neurol AMPA receptors being actually heterotetramers composed of AMPA1 plus AMPA2 or AMPA2 plus AMPA3, although homotetramers can also be found. AMPA receptors are permeable to cations + and K+ and Ca2+. The Ca2+ permeability is dependent on the presence of AMPA2: whenever this subunit is present, the channel will be impermeable to Ca2+. The Ca2+ permeability of the AMPA2 subunit is determined by the presence of an arginine (R) at a critical site in the pore loop instead of a glutamine (Q) present in the same site in the other AMPA subunits. A post-transcriptiol process known as R editing determines the presence of this R. Since most AMPA2 subunits in the adult brain have undergone R editing and most AMPA receptors contain the AMPA2 subunit, most tive AMPA receptors will be impermeable to Ca2+. Gating of AMPA receptors by glutamate is extremely fast and therefore the AMPA receptors mediate most excitatory (depolarizing) currents in the brain during basal neurol activity. The depolarization caused by the activation of post-syptic AMPA receptors is necessary for the activation of NMDA receptors that will open only in the presence of both glutamate and a depolarized membrane. Syptic strength, defined as the level of post-syptic depolarization, can be long term (hence the term long term potentiation, LTP) and therefore induce changes in sigling and protein synthesis in the activated neuron. These changes are associated with memory formation and learning. Changes in syptic strength are thought to involve rapid movement of the AMPA receptors in and out of the sypses and a great deal of effort has focused in understanding the mechanisms that govern AMPA receptor trafficking.

  1. Quick-Filters:
  2. Cited (3)

Items 1 to 20 of 69 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glutamate receptor 1 / GLUR1 (N-term) antibody

Western blot of rat hippocampal lysate showing specific immunolabeling Mouse IgG2a RH95 Purified Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 1 / GLUR1 pSer831 antibody

Figure 1.Western blot of rat hippocampal lysate showing specific immunolabeling of the ~100k GluR1 protein phosphorylated at Ser831 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase). The blot is identical to the control except that it was incubated in lambda-Ptase (1200 units for 30 min) before being exposed to the GluR1 Ser831 antibody. The immunolabeling is completely eliminated by treatment with lambda-Ptase. Rabbit IgG Aff - Purified Can, Chk, Hu, Ms, Rt WB
0.15 ml / €380.00
  Acris Antibodies GmbH

Glutamate receptor 1 / GLUR1 pSer845 antibody

Figure 1. Western blot of rat hippocampal lysate showing specific immunolabeling of the ~100k GluR1 protein phosphorylated at Ser845 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase). The blot is identical to the control except that it was incubated in lambda-Ptase (1200 units for 30 min) before being exposed to the GluR1 Ser845 antibody. The immunolabeling is completely eliminated by treatment with lambda-Ptase. Rabbit IgG Aff - Purified Hu, Ms, non-Human Primates, Rt ICC/IF, WB
0.15 ml / €380.00
  Acris Antibodies GmbH

Glutamate receptor 1 / GLUR1 (264-277) antibody

AP31107PU-N GLUR1 antibody staining of Human Cerebellum lysate at 0.1 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Glutamate receptor 1 / GLUR1 antibody

Predicted band size: 101 kDa . Positive control: Mouse brain tissue lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lysate: 60 ug Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 1 / GLUR1 antibody

Western blot analysis of GluR1 expression in COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 1 / GLUR1 (1-389, Extracell. Dom.) antibody

Glutamate receptor 1 / GLUR1 Mouse IgG1 S355-1 Purified Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 1 / GLUR1 antibody

Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain lysates: 1, 2. Anti-AMPA Receptor 1 (GluA1) (extracellular) antibody, (1:200). 3, 4. Anti-AMPA1 Receptor 1 (GluA1) (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Glutamate receptor 1 / GLUR1 antibody

Western blot analysis of extracts of Rat brain cell line, using GRIA1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 1 / GLUR1 antibody

Glutamate receptor 1 / GLUR1 Mouse IgG1 N355/1 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Glutamate receptor 1 / GLUR1 antibody

Glutamate receptor 1 / GLUR1 Mouse IgG1 N355/1 Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Glutamate receptor 1 / GLUR1 pSer849 antibody

Western blot analysis of extract from mouse brain tissue, using GluR1 antibody (Lane 1 and 2) and GluR1 (pSer849) antibody (AP02510PU-S; AP02510PU-N, Lane 3 and 4). Rabbit Aff - Purified Hu, Ms WB
0.1 ml / €320.00
  Acris Antibodies GmbH

Glutamate receptor 1 / GLUR1 pSer849 antibody

Western blot analysis of extract from mouse brain tissue, using GluR1 antibody (Lane 1 and 2) and GluR1 (pSer849) antibody (AP02510PU-S; AP02510PU-N, Lane 3 and 4). Rabbit Aff - Purified Hu, Ms WB
50 µl / €240.00
  Acris Antibodies GmbH

Glutamate receptor 1 / GLUR1 antibody

Western blot analysis of extracts from C6 and PC12 using GluR1 antibody (AP02755PU-S; AP02755PU-N). Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Acris Antibodies GmbH

Glutamate receptor 1 / GLUR1 antibody

Western blot analysis of extracts from C6 and PC12 using GluR1 antibody (AP02755PU-S; AP02755PU-N). Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €230.00
  Acris Antibodies GmbH

Glutamate receptor 1 / GLUR1 pSer831 antibody

Western blot analysis using GluR1 Ser831 antibody on rat brain lysate in the absence and presence of antigen peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt Dot, WB
10 Blots / €460.00
  Acris Antibodies GmbH

Glutamate receptor 1 / GLUR1 pSer845 antibody

Western blot analysis using GluR1 Ser845 antibody on rat brain lysate in the absence and presence of antigen peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt WB
10 Blots / €460.00
  Acris Antibodies GmbH

Glutamate receptor 1 / GLUR1 (C-term) antibody

Glutamate receptor 1 / GLUR1 Rabbit IgG Purified Hst, Hu, Mky, Rt C, WB
50 µg / €400.00
  Acris Antibodies GmbH

Glutamate receptor 1 / GLUR1 pSer831 antibody

Glutamate receptor 1 / GLUR1 Rabbit IgG Purified Can, Chk, Hu, Ms, Rt WB
0.15 ml / €510.00
  Acris Antibodies GmbH

Glutamate receptor 1 / GLUR1 pSer845 antibody

Glutamate receptor 1 / GLUR1 Rabbit IgG Purified Hu, Mky, Ms, Rt WB
0.15 ml / €510.00
  Acris Antibodies GmbH

Items 1 to 20 of 69 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  • LinkedIn