Glutamate receptor 3 / GLUR3 antibody

Principal name

Glutamate receptor 3 / GLUR3 antibody

Alternative names for Glutamate receptor 3 / GLUR3 antibody

GluR-3, GluR-C, GluR-K3, Glutamate receptor ionotropic AMPA3, GRIA3, GLURC, GluA3, AMPA-selective glutamate receptor

SwissProt ID

P19492 (Rat), P42263 (Human), Q9Z2W9 (Mouse)

Gene ID

2892 (GRIA3), 1028928 (P72477), 53623 (Gria3), 29628

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Paraffin Sections (P), Frozen Sections (C)

Background of Glutamate receptor 3 / GLUR3 antibody

L-Glutamate, the major excitatory neurotransmitter in the central nervous system, operates through several receptors that are categorized as ionotropic (ligand-gated cation channels) or metabotropic (G-protein coupled receptors). The ligand-gated ion channel family consists of 15 members that have been subdivided into three families based on their pharmacological profile: the a-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (AMPA) preferring receptors, the N-methyl-D-aspartate (NMDA) preferring and the kaite preferring receptors. The AMPA receptor subfamily includes four members AMPA1 to AMPA4, also known as GluR1 to GluR4 respectively. The functiol AMPA channel is believed to be a tetramer, with most neurol AMPA receptors being heterotetramers composed of AMPA1 plus AMPA2 or AMPA2 plus AMPA3 channels, although homotetramers can also been found. AMPA receptors are permeable to cations +, K+ and Ca2+. The Ca2+ permeability is dependent on the presence of AMPA2: whenever this subunit is present, the channel will be impermeable to Ca2+. Gating of AMPA receptors by glutamate is extremely fast and therefore the AMPA receptors mediate most excitatory (depolarizing) currents in the brain during basal neurol activity. The depolarization caused by the activation of post-syptic AMPA receptors is necessary for the activation of NMDA receptors that will open only in the presence of both glutamate and a depolarized membrane potential. Syptic strength that is defined as the level of post-syptic depolarization can be long term (hence the term long term potentiation, LTP) and therefore induce changes in sigling and protein synthesis in the activated neuron. These changes are associated with memory formation and learning. Changes in syptic strength are thought to involve rapid movement of the AMPA receptors in and out of the sypses and a great deal of effort has focused in understanding the mechanisms that govern AMPA receptor trafficking. The exact physiological role of the AMPA3 receptor is not clear but a role in the modulation of oscillatory networks affecting sleep and breathing has been suggested.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glutamate receptor 3 / GLUR3 antibody

Western blot analysis of brian cell lysate using GRIA3 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 3 / GLUR3 antibody

Western blot of rat hippocampal lysate showing specific immunolabeling of the ~100k GluR2/3 protein. Rabbit IgG Purified Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 3 / GLUR3 antibody

Predicted cell location: Cytoplasm. Positive control: Human tonsil tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using GRIA3 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 3 / GLUR3 antibody

Predicted cell location: Cytoplasm. Positive control: Human lung and ovarian cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human lung and ovarian cancer tissue using GRIA3 antibody at dilution 1/50, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 3 / GLUR3 antibody

Western blot analysis of rat cerebellum lysates: 1. Anti-AMPA Receptor 3 (GluA3) (extracellular) antibody, (1:400). 2. Anti-AMPA Receptor 3 (GluA3) (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Glutamate receptor 3 / GLUR3 antibody

Host: Rabbit; Target Name: Gria3; Sample Tissue: Rat Stomach lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 3 / GLUR3 antibody

WB Suggested Anti-Gria3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:2500; Positive Control: Mouse Liver Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 3 / GLUR3 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissues (left) and rat brain tissues (right) using GRIA3 mouse mAb with DAB staining. Mouse IgG1 1D2 Ascites Hu E, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

Glutamate receptor 3 / GLUR3 antibody

Glutamate receptor 3 / GLUR3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Glutamate receptor 3 / GLUR3 antibody

Western Blot analysis of GRIA3 expression in transfected 293T cell line (H00002892-T01) by GRIA3 MaxPab polyclonal antibody.

Lane 1: GRIA3 transfected lysate(15.84 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Glutamate receptor 3 / GLUR3 antibody

Glutamate receptor 3 / GLUR3 Mouse IgG2a 3D10 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

Glutamate receptor 3 / GLUR3 (N-term) antibody

Mouse Liver; WB Suggested Anti-Gria3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:2500. Positive Control: Mouse Liver; Gria3 antibody - N-terminal region (ARP35200_P050) in Mouse Liver cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

Glutamate receptor 3 / GLUR3 antibody

Glutamate receptor 3 / GLUR3 Rabbit Purified Hu, Ms, Rt P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Glutamate receptor 3 / GLUR3

Glutamate receptor 3 / GLUR3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Glutamate receptor 3 / GLUR3

Glutamate receptor 3 / GLUR3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Glutamate receptor 3 / GLUR3

Glutamate receptor 3 / GLUR3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Glutamate receptor 3 / GLUR3

Glutamate receptor 3 / GLUR3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GRIA3 293T Cell Transient Overexpression Lysate(Denatured)

GRIA3 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

18 Item(s)

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