Glutamate receptor 6 / GLUR6 antibody

Principal name

Glutamate receptor 6 / GLUR6 antibody

Alternative names for Glutamate receptor 6 / GLUR6 antibody

GRIK2, Excitatory amino acid receptor 4, EAA4, Glutamate receptor ionotropic kainate 2

SwissProt ID

P39087 (Mouse), P42260 (Rat), Q13002 (Human), Q91755 (Xenla)

Gene ID

2898 (GRIK2), 54257 (Grik2)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Chk (Chicken), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Enzyme Immunoassay (E), Frozen Sections (C)

Background of Glutamate receptor 6 / GLUR6 antibody

L-Glutamate, the major excitatory neurotransmitter in the central nervous system (CNS), operates through several receptors that are categorized as ionotropic (ligand-gated cation channels) or metabotropic (G-protein-coupled receptors). The ligand-gated ion channel family consists of fifteen members that have been subdivided into three families based upon their pharmacological profile: the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-preferring receptors, the N-methyl-D-aspartate (NMDA)-preferring receptors, and the kaite-preferring receptors. The kaite receptor subfamily consists of five members that have been further subdivided into two classes based upon structural homology and functiol characteristics. GluR5, GluR6, and GluR7 receptor subunits share a high degree of homology and are able to form functiol channels when expressed in heterologous systems. The KA-1 and KA-2 receptors are uble to form functiol channels on their own, but when coexpressed with GluR5-7 receptor subunits, they form channels with high affinity for kaite. Like AMPA receptors, the functiol unit of endogenous kaite receptors is believed to be a tetramer, which can be either homomeric or heteromeric. Kaite receptors GluR5 and GluR6 (but not GluR7, KA-1, or KA-2) can undergo R editing; as in the AMPA receptor GluR2, a glutamine (Q) residue in the channel pore is edited to encode arginine (R) in the mature protein. Substitution of Q with R modulates the properties of the channel, producing channels with reduced single channel conductance and lower permeability to Ca2+. GluR6 is expressed in the CNS in basal ganglia, cerebellum, and hipoccampus, as well as in the spil cord. The exact physiological role of GluR6 is unclear, but a role in controlling neurol excitability, syptic integration, and syptic plasticity has been proposed.

General readings

Bah,J., et al., (2004) Neuroreport 15 (12), 1987-1991

  1. Quick-Filters:
  2. Highly Validated (1)

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glutamate receptor 6 / GLUR6 antibody

Immunohistochemistry-Paraffin: Glutamate receptor 6 Antibody [NBP1-46485] - Rat spinal cord (paraffin section) using Rabbit antibody to 1t extracellular domain of GRIK2 (GLUR6, Glutamate receptor 6): whole serum at 1 : 200 dilution, incubated overnight at 4C, developed with DAB/Ni and counterstained with hemato Rabbit Purified Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Glutamate receptor 6 / GLUR6 (+ GLUR7) antibody

Human brain stained with Anti-GluR6/7 antibody Rabbit Purified Chk, Hu, Mky, Ms, Rt IP, P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

Glutamate receptor 6 / GLUR6 (+ GLUR7) antibody

Human brain stained with Anti-GluR6/7 antibody Rabbit Purified Chk, Hu, Mky, Ms, Rt IP, P, WB
1 ml / €490.00
  Acris Antibodies GmbH

Glutamate receptor 6 / GLUR6 (+ GLUR7) antibody

Human brain stained with Anti-GluR6/7 antibody Rabbit Purified Chk, Hu, Mky, Ms, Rt IP, P, WB
0.1 ml / €190.00
  Acris Antibodies GmbH

Glutamate receptor 6 / GLUR6 (C-term) antibody

Western blot analysis of Grik2 in human brain tissue lysate with Grik2 antibody at (A) 0.5 and (B) 1 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 6 / GLUR6 antibody

Western blot analysis of mouse (lanes 1 and 3) and rat (lanes 2 and 4) brain membranes: 1, 2. Anti-Kainate Receptor GluK2 antibody, (1:400). 3, 4. Anti-Kainate Receptor GluK2 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Glutamate receptor 6 / GLUR6 antibody

Western blot analysis of extracts of various cell lines, using GRIK2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 6 / GLUR6 antibody

WB Suggested Anti-GRIK2 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 6 / GLUR6 antibody

WB Suggested Anti-GRIK2 Antibody Titration: 0.125 ug/ml; ELISA Titer: 1:62500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 6 / GLUR6 (841-890) antibody

Immunohistochemistry (IHC) analysis of GluR6 antibody (Cat.-No. AP06141PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Glutamate receptor 6 / GLUR6 Control Peptide

Glutamate receptor 6 / GLUR6
50 µg / €160.00
  Acris Antibodies GmbH

Glutamate receptor 6 / GLUR6 (N-term) antibody

Glutamate receptor 6 / GLUR6 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Glutamate receptor 6 / GLUR6 antibody

Western Blot analysis of GRIK2 expression in transfected 293T cell line (H00002898-T03) by GRIK2 MaxPab polyclonal antibody.

Lane 1: GRIK2 transfected lysate(38.94 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Glutamate receptor 6 / GLUR6 antibody

Glutamate receptor 6 / GLUR6 Rabbit Hu WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Glutamate receptor 6 / GLUR6 antibody

Glutamate receptor 6 / GLUR6 Rabbit Hu IP, P, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Glutamate receptor 6 / GLUR6 antibody

Human Jurkat; WB Suggested Anti-GRIK2 Antibody Titration: 2.5ug/ml. ELISA Titer: 1:62500. Positive Control: Jurkat cell lysate; GRIK2 antibody - N-terminal region (ARP35340_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

Glutamate receptor 6 / GLUR6 antibody

Human Brain; WB Suggested Anti-GRIK2 Antibody Titration: 0.125ug/ml. ELISA Titer: 1:62500. Positive Control: Human brain; GRIK2 antibody - C-terminal region (ARP35341_P050) in Human Brain cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Glutamate receptor 6 / GLUR6 (N-term) antibody

Human kidney; GRIK2 antibody - N-terminal region (ARP35515_T100) in Human kidney cells using Immunohistochemistry Rabbit IgG Purified African clawed frog, Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

Glutamate receptor 6 / GLUR6 antibody

Immunohistochemistry-Paraffin: Glutamate receptor 6 Antibody [NBP1-91946] - Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Glutamate receptor 6 / GLUR6 (transcript variant 1)

Glutamate receptor 6 / GLUR6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn