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Home » Target » Glutamate receptor 6 / GLUR6 antibody

Glutamate receptor 6 / GLUR6 antibody

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Principal name

Glutamate receptor 6 / GLUR6 antibody

Alternative names for Glutamate receptor 6 / GLUR6 antibody

GRIK2, Excitatory amino acid receptor 4, EAA4, Glutamate receptor ionotropic kainate 2

SwissProt ID

P39087 (Mouse), P42260 (Rat), Q13002 (Human), Q91755 (Xenla)

Gene ID

2898 (GRIK2), 54257 (Grik2)

Ncbi ID

NP_786944, 9606, NP_001159719.1, NP_068775, AAH63814.1, Q13002, NP_062182.1, NM_019309, NM_021956, NM_175768

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Chk (Chicken), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Frozen Sections (C), Enzyme Immunoassay (E)

Background of Glutamate receptor 6 / GLUR6 antibody

L-Glutamate, the major excitatory neurotransmitter in the central nervous system (CNS), operates through several receptors that are categorized as ionotropic (ligand-gated cation channels) or metabotropic (G-protein-coupled receptors). The ligand-gated ion channel family consists of fifteen members that have been subdivided into three families based upon their pharmacological profile: the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-preferring receptors, the N-methyl-D-aspartate (NMDA)-preferring receptors, and the kaite-preferring receptors. The kaite receptor subfamily consists of five members that have been further subdivided into two classes based upon structural homology and functiol characteristics. GluR5, GluR6, and GluR7 receptor subunits share a high degree of homology and are able to form functiol channels when expressed in heterologous systems. The KA-1 and KA-2 receptors are uble to form functiol channels on their own, but when coexpressed with GluR5-7 receptor subunits, they form channels with high affinity for kaite. Like AMPA receptors, the functiol unit of endogenous kaite receptors is believed to be a tetramer, which can be either homomeric or heteromeric. Kaite receptors GluR5 and GluR6 (but not GluR7, KA-1, or KA-2) can undergo R editing; as in the AMPA receptor GluR2, a glutamine (Q) residue in the channel pore is edited to encode arginine (R) in the mature protein. Substitution of Q with R modulates the properties of the channel, producing channels with reduced single channel conductance and lower permeability to Ca2+. GluR6 is expressed in the CNS in basal ganglia, cerebellum, and hipoccampus, as well as in the spil cord. The exact physiological role of GluR6 is unclear, but a role in controlling neurol excitability, syptic integration, and syptic plasticity has been proposed.

General readings

Bah,J., et al., (2004) Neuroreport 15 (12), 1987-1991

ARP35341_P050 - Glutamate receptor 6 / GLUR6
Human Brain; WB Suggested Anti-GRIK2 Antibody Titration: 0.125ug/ml. ELISA Titer: 1:62500. Positive Control: Human brain; GRIK2 antibody - C-terminal region (ARP35341_P050) in Human Brain cells using Western Blot
ARP35340_T100 - Glutamate receptor 6 / GLUR6
Human Jurkat; WB Suggested Anti-GRIK2 Antibody Titration: 2.5ug/ml. ELISA Titer: 1:62500. Positive Control: Jurkat cell lysate; GRIK2 antibody - N-terminal region (ARP35340_T100) in Human Jurkat cells using Western Blot
ARP35515_T100 - Glutamate receptor 6 / GLUR6
Human kidney; GRIK2 antibody - N-terminal region (ARP35515_T100) in Human kidney cells using Immunohistochemistry
ARP35515_T100 - Glutamate receptor 6 / GLUR6
Mouse cortex brain; . Lanes: Lane1: 10ug mouse cortex brain lysate. Lane2: 25ug mouse cortex brain lysate. Lane3: 40ug mouse cortex brain lysate. Primary Antibody Dilution: 1:1000. Secondary Antibody: Anti-rabbit HRP. Secondary Antibody Dilution: 1:2000. Gene Name: GRIK2. Submitted by: Anonymous.; GRIK2 antibody - N-terminal region (ARP35515_T100) in Mouse cortex brain cells using Western Blot
ARP35515_T100 - Glutamate receptor 6 / GLUR6
Human Jurkat; WB Suggested Anti-GRIK2 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:1562500. Positive Control: Jurkat cell lysate; GRIK2 antibody - N-terminal region (ARP35515_T100) in Human Jurkat cells using Western Blot
AP06141PU-N - Glutamate receptor 6 / GLUR6
Immunohistochemistry (IHC) analysis of GluR6 antibody (Cat.-No. AP06141PU-N) in paraffin-embedded human brain tissue.
AP06141PU-N - Glutamate receptor 6 / GLUR6
Western blot (WB) analysis of mGluR-6 antibody (Cat.-No AP06141PU-N) at 1/500 dilution:
Lane 1: Hela whole cell lysate
Lane 2: NIH-3T3 whole cell lysate
Lane 3: Raw264.7 whole cell lysate
Lane 4: H9C2 whole cell lysate
AP06141PU-N - Glutamate receptor 6 / GLUR6
Immunohistochemistry (IHC) analysis of GluR6 antibody (Cat.-No AP06141PU-N) in paraffin-embedded human breast carcinoma tissue at 1/50 dilution.
H00002898-B01 - Glutamate receptor 6 / GLUR6
Western Blot analysis of GRIK2 expression in transfected 293T cell line (H00002898-T03) by GRIK2 MaxPab polyclonal antibody.Lane 1: GRIK2 transfected lysate(38.94 KDa).Lane 2: Non-transfected lysate.
AP15581PU-S - Glutamate receptor 6 / GLUR6
Human brain stained with Anti-GluR6/7 antibody
TP322369 - Glutamate receptor 6 / GLUR6
TP323048 - Glutamate receptor 6 / GLUR6
TA306496 - Glutamate receptor 6 / GLUR6
Western blot analysis of Grik2 in human brain tissue lysate with Grik2 antibody at (A) 0.5 and (B) 1 µg/ml.
TA328828 - Glutamate receptor 6 / GLUR6
Western blot analysis of mouse (lanes 1 and 3) and rat (lanes 2 and 4) brain membranes: 1, 2. Anti-Kainate Receptor GluK2 antibody, (1:400). 3, 4. Anti-Kainate Receptor GluK2 antibody, preincubated with the control peptide antigen.
TA328828 - Glutamate receptor 6 / GLUR6
Expression of GluR6 in rat DRG neurons. Immunocytochemistry of rat dorsal root ganglion (DRG) neurons. A. Paraformaldehyde-fixed and permeabilized DRG neurons were labeled with Anti-Kainate Receptor GluK2 antibody, (1:400) followed by goat anti-rabbit-AlexaFluor-555 secondary antibody. B. Nuclei were visualized with the cell permeable dye Hoechst 33342 (blue). C. Merged figure of A and B.
TA332468 - Glutamate receptor 6 / GLUR6
Western blot analysis of extracts of various cell lines, using GRIK2 antibody.
TA332468 - Glutamate receptor 6 / GLUR6
Immunofluorescence analysis of U2OS cell using GRIK2 antibody. Blue: DAPI for nuclear staining.
TA338702 - Glutamate receptor 6 / GLUR6
WB Suggested Anti-GRIK2 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate
TA338703 - Glutamate receptor 6 / GLUR6
WB Suggested Anti-GRIK2 Antibody Titration: 0.125 ug/ml; ELISA Titer: 1:62500; Positive Control: Human brain

19 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glutamate receptor 6 / GLUR6 (C-term) antibody
  Rabbit Polyclonal Grik2 Antibody  
Western blot analysis of Grik2 in human brain tissue lysate with Grik2 antibody at (A) 0.5 and (B) 1 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 6 / GLUR6 antibody
  Rabbit Polyclonal Anti-Kainate Receptor GluK2  
Western blot analysis of mouse (lanes 1 and 3) and rat (lanes 2 and 4) brain membranes: 1, 2. Anti-Kainate Receptor GluK2 antibody, (1:400). 3, 4. Anti-Kainate Receptor GluK2 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.
+1 additional image

Glutamate receptor 6 / GLUR6 antibody
  Rabbit anti-GRIK2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using GRIK2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.
+1 additional image

Glutamate receptor 6 / GLUR6 antibody
  Rabbit Polyclonal Anti-GRIK2 Antibody  
WB Suggested Anti-GRIK2 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 6 / GLUR6 antibody
  Rabbit Polyclonal Anti-GRIK2 Antibody  
WB Suggested Anti-GRIK2 Antibody Titration: 0.125 ug/ml; ELISA Titer: 1:62500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor 6 / GLUR6 (841-890) antibody
Immunohistochemistry (IHC) analysis of GluR6 antibody (Cat.-No. AP06141PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH
+2 additional images

Glutamate receptor 6 / GLUR6 (N-term) antibody
Glutamate receptor 6 / GLUR6 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

GRIK2 - human gene knockout kit via CRISPR
GRIK2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GRIK2 - human gene knockout kit via CRISPR
GRIK2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GRIK2 - human gene knockout kit via CRISPR
GRIK2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GRIK2 - human gene knockout kit via CRISPR
GRIK2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Glutamate receptor 6 / GLUR6 (transcript variant 1)
  Recombinant protein of human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1  
Glutamate receptor 6 / GLUR6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Glutamate receptor 6 / GLUR6 (transcript variant 2)
  Recombinant protein of human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 2  
Glutamate receptor 6 / GLUR6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GRIK2 (mGFP-tagged) - Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, GRIK2 (mGFP-tagged) - Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,900.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, GRIK2 (mGFP-tagged) - Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, GRIK2 (mGFP-tagged) - Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,840.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, GRIK2 (Myc-DDK tagged) - Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1 , 200 uL, >10^7 TU/mL
Lenti ORF particles, GRIK2 (Myc-DDK tagged) - Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,710.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, GRIK2 (Myc-DDK tagged) - Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 2 , 200 uL, >10^7 TU/mL
Lenti ORF particles, GRIK2 (Myc-DDK tagged) - Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €1,660.00
  OriGene Technologies, Inc.
 

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Grik2 (GFP-tagged ORF) - Rat glutamate receptor, ionotropic, kainate 2 (Grik2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Grik2 (GFP-tagged ORF) - Rat glutamate receptor, ionotropic, kainate 2 (Grik2), 200 uL, >10^7 TU/mL  
200 µl / €1,660.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Grik2 (Myc-DDK-tagged ORF) - Rat glutamate receptor, ionotropic, kainate 2 (Grik2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Grik2 (Myc-DDK-tagged ORF) - Rat glutamate receptor, ionotropic, kainate 2 (Grik2), 200 uL, >10^7 TU/mL  
200 µl / €1,491.00
  OriGene Technologies, Inc.
 

19 Item(s)

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19 products - FILTER YOUR RESULTS!

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Clonality
  1. Polyclonal (7)
Target
  1. Glutamate receptor 6 / GLUR6 (9)
Property
  1. 841-890 (1)
  2. C-term (1)
  3. N-term (1)
Reactivity
  1. Human (Hu) (7)
  2. Mouse (Ms) (5)
  3. Rat (Rt) (5)
  4. Bovine (Bov) (2)
  5. Canine (Can) (2)
  6. Equine (Eq) (2)
  7. Guinea Pig (GP) (2)
  8. Porcine (Por) (2)
  9. Rabbit (Rb) (2)
  10. Zebrafish (Ze) (2)
Applications
  1. Western blot / Immunoblot (WB) (6)
  2. Enzyme Immunoassay (E) (2)
  3. Frozen sections (C) (1)
  4. Paraffin Sections (P) (1)
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Images
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  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (6)
  2. Immunofluorescence (IF) (2)
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Species (Protein)
  1. Human (2)
Source
  1. HEK293 cells (2)
Species (CRISPR)
  1. Human (4)
Donor Vector
  1. GFP-Puro (1)
  2. Luciferase-Puro (1)
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