Glutamate receptor delta-1 antibody

Principal name

Glutamate receptor delta-1 antibody

Alternative names for Glutamate receptor delta-1 antibody

GluR delta-1, GRID1, KIAA1220

SwissProt ID

Q61627 (Mouse), Q62640 (Rat), Q9ULK0 (Human)

Gene ID

2894 (GRID1), 79219 (Grid1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Glutamate receptor delta-1 antibody

Excitatory neurotransmission in the vertebrate central nervous system is mainly mediated by ionotropic glutamate receptors (iGluRs). Molecular cloning identified 18 mammalian iGluR subunits, of which only 16 sort into the traditiol pharmacological subfamilies of AMPA, kaite (KA), and N-methyl-D-aspartate (NMDA) receptors. The 2 remaining subunits were termed â??orphanâ? receptors, â??glutamate-likeâ? receptors, â??nonionotropicâ? receptors, or, most commonly, delta receptors.Ionotropic glutamate receptors are integral membrane proteins composed of four large subunits that form a central ion channel pore. Sequence similarity among all known glutamate receptor subunits, including the d receptors, suggests they share a similar architecture. Glutamate receptor subunits are modular structures that contain four discrete semiautonomous domains: the extracellular amino-termil domain (ATD), the extracellular ligand-binding domain (LBD), the transmembrane domain (TMD), and an intracellular carboxyl-termil domain (CTD). The delta family of ionotropic glutamate receptors (iGluRs) consists of the glutamate d1 (GluD1) and glutamate d2 (GluD2) receptors. GluD1 is highly expressed in the inner hair cells of the organ of Corti, diffusely expressed throughout the forebrain during development with high levels in the hippocampus during adulthood. Deletion of GluD1 leads to a deficit in high frequency hearing in mice5. Genetic association studies have established the GRID1 gene, which codes for GluD1, is a strong candidate gene for schizophrenia, bipolar disorder, and major depressive disorder6. Copy number variation studies have also implicated GRID1 in autism spectrum disorder (ASD). In addition, GRID1 gene is localized to the 10q22â??q23 genomic region which is a site for recurrent deletions associated with cognitive and behavioral abnormalities.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glutamate receptor delta-1 antibody

Western blot analysis of human CCF-STTG1 astrocytoma cell lysate (lanes 1 and 4), mouse brain lysate (lanes 2 and 5) and rat brain lysate (lines 3 and 6): 1-3. Anti-Glutamate Receptor d1 (GluD1) (extracellular) antibody , (1:200). 4-6. Anti-Glutamate Receptor d1 (GluD1) (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Glutamate receptor delta-1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GRID1 (RC224397, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GRID1. Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Glutamate receptor delta-1 antibody

Glutamate receptor delta-1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Glutamate receptor delta-1 antibody

Glutamate receptor delta-1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Glutamate receptor delta-1 antibody

GRID1 monoclonal antibody (M01), clone 1A9 Western Blot analysis of GRID1 expression in HeLa ( Cat # L013V1 ). Mouse IgG2b 1A9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Glutamate receptor delta-1 antibody

Glutamate receptor delta-1 Mouse IgG2b 3A8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Glutamate receptor delta-1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GRID1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

Glutamate receptor delta-1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GRID1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

Glutamate receptor delta-1 antibody

Glutamate receptor delta-1 Rabbit Aff - Purified Hu P, WB
50 µg / €400.00
  Novus Biologicals Inc.

Glutamate receptor delta-1 antibody

Glutamate receptor delta-1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Glutamate receptor delta-1 antibody

Glutamate receptor delta-1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Glutamate receptor delta-1

Glutamate receptor delta-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Glutamate receptor delta-1

Glutamate receptor delta-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

13 Item(s)

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