Glutamyl cyclase / QPCT antibody

Principal name

Glutamyl cyclase / QPCT antibody

Alternative names for Glutamyl cyclase / QPCT antibody

Glutaminyl-peptide cyclotransferase, Glutaminyl-tRNA cyclotransferase

SwissProt ID

Q16769 (Human), Q28120 (Bovin), Q9CYK2 (Mouse)

Gene ID

25797 (QPCT), 70536 (Qpct)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of Glutamyl cyclase / QPCT antibody

QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Cynis,H., (2008) J. Mol. Biol. 379 (5), 966-980

12 Item(s)

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CRISPR

Catalog No. Species Donor Vector  

Qpct - mouse gene knockout kit via CRISPR

Qpct - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Qpct - mouse gene knockout kit via CRISPR

Qpct - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Qpct - mouse gene knockout kit via CRISPR

Qpct - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Qpct - mouse gene knockout kit via CRISPR

Qpct - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Glutamyl cyclase / QPCT

  Recombinant protein of human glutaminyl-peptide cyclotransferase (QPCT)  
Glutamyl cyclase / QPCT Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

QPCT overexpression lysate

QPCT overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, QPCT (mGFP-tagged) - Human glutaminyl-peptide cyclotransferase (QPCT), 200 uL, >10^7 TU/mL

Lenti ORF particles, QPCT (mGFP-tagged) - Human glutaminyl-peptide cyclotransferase (QPCT), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, QPCT (Myc-DDK tagged) - Human glutaminyl-peptide cyclotransferase (QPCT) , 200 uL, >10^7 TU/mL

Lenti ORF particles, QPCT (Myc-DDK tagged) - Human glutaminyl-peptide cyclotransferase (QPCT) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Qpct (GFP-tagged) - Mouse glutaminyl-peptide cyclotransferase (glutaminyl cyclase) (cDNA clone MGC:27858 IMAGE:3491756), 200 uL, >10^7 TU/mL

Lenti ORF particles, Qpct (GFP-tagged) - Mouse glutaminyl-peptide cyclotransferase (glutaminyl cyclase) (cDNA clone MGC:27858 IMAGE:3491756), 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Qpct (GFP-tagged) - Mouse glutaminyl-peptide cyclotransferase (glutaminyl cyclase) (Qpct), 200 uL, >10^7 TU/mL

Lenti ORF particles, Qpct (GFP-tagged) - Mouse glutaminyl-peptide cyclotransferase (glutaminyl cyclase) (Qpct), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Qpct (Myc-DDK-tagged) - Mouse glutaminyl-peptide cyclotransferase (glutaminyl cyclase) (cDNA clone MGC:27858 IMAGE:3491756), 200 uL, >10^7 TU/mL

Lenti ORF particles, Qpct (Myc-DDK-tagged) - Mouse glutaminyl-peptide cyclotransferase (glutaminyl cyclase) (cDNA clone MGC:27858 IMAGE:3491756), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Qpct (Myc-DDK-tagged) - Mouse glutaminyl-peptide cyclotransferase (glutaminyl cyclase) (Qpct), 200 uL, >10^7 TU/mL

Lenti ORF particles, Qpct (Myc-DDK-tagged) - Mouse glutaminyl-peptide cyclotransferase (glutaminyl cyclase) (Qpct), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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