Glutaredoxin-2 / GLRX2 antibody

Principal name

Glutaredoxin-2 / GLRX2 antibody

Alternative names for Glutaredoxin-2 / GLRX2 antibody

Glutaredoxin-2 mitochondrial, GRX2, grxB

SwissProt ID

P0AC59 (Ecoli), P17695 (Yeast), Q32L67 (Bovin), Q6AXW1 (Rat), Q923X4 (Mouse), Q9NS18 (Human), Q9UTI2 (Schpo)

Gene ID

51022 (GLRX2), 946926 (grxB), 69367 (Glrx2), 114022

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F)

Background of Glutaredoxin-2 / GLRX2 antibody

GLRX2 (Glutaredoxin-2) also known as Glutaredoxin-2, mitochondrial or GRX2, is a protein that in humans is encoded by the GLRX2 gene. Glutaredoxins (e.g., GLRX) are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. By sequence analysis, Lundberg et al. (2001) and Gladyshev et al. (2001) identified the GLRX2 gene within a clone mapping to chromosome 1q31.2-q31.3. Lundberg et al. (2001) determined that the GLRX2 gene contains 5 exons spanning about 9.6 kb. The GLRX2B transcript uses a first exon (exon 1B) located upstream from the first exon used by the GLRX2A transcript (exon 1A), suggesting that alternative splicing generates the isoforms. Lundberg et al. (2001)assayed reductase activity in recombinant proteins of both GLRX2 isoforms. They found that both have GSH-dependent dehydroascorbate reductase activity and 2-hydroxyethyl disulfide reductase activity.

General readings

Holmgren A, et al. (2004) Antioxid. Redox. Signal. 6 (1): 63–74.
López-Maury L, et al. (2009) J Bacteriol. 191(11):3534-43.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glutaredoxin-2 / GLRX2 antibody

  Rabbit Polyclonal Anti-GLRX2 Antibody - middle region  
WB Suggested Anti-GLRX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

Glutaredoxin-2 / GLRX2 (C-term) antibody

Figure 2. AP20046PU-N Glutaredoxin-2 Antibody staining of Formalin-Fixed and Paraffin-Embedded Human brain. This antibody was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

GLRX2 - human gene knockout kit via CRISPR

GLRX2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GLRX2 - human gene knockout kit via CRISPR

GLRX2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GLRX2 - human gene knockout kit via CRISPR

GLRX2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GLRX2 - human gene knockout kit via CRISPR

GLRX2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Glrx2 - mouse gene knockout kit via CRISPR

Glrx2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Glrx2 - mouse gene knockout kit via CRISPR

Glrx2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Glrx2 - mouse gene knockout kit via CRISPR

Glrx2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Glrx2 - mouse gene knockout kit via CRISPR

Glrx2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Glutaredoxin-2 / GLRX2 (transcript variant 1)

  Recombinant protein of human glutaredoxin 2 (GLRX2), transcript variant 1  
Glutaredoxin-2 / GLRX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Glutaredoxin-2 / GLRX2 (20-164, His-tag)

Glutaredoxin-2 / GLRX2 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €670.00
  Acris Antibodies GmbH

Glutaredoxin-2 / GLRX2 (20-164, His-tag)

Glutaredoxin-2 / GLRX2 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €250.00
  Acris Antibodies GmbH

Glutaredoxin-2 / GLRX2 (1-215, His-tag)

Glutaredoxin-2 / GLRX2 E. coli Purified > 95 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

Glutaredoxin-2 / GLRX2 (1-215, His-tag)

Glutaredoxin-2 / GLRX2 E. coli Purified > 95 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

GLRX2 overexpression lysate

GLRX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GLRX2 (mGFP-tagged) - Human glutaredoxin 2 (GLRX2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, GLRX2 (mGFP-tagged) - Human glutaredoxin 2 (GLRX2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, GLRX2 (mGFP-tagged)-Human glutaredoxin 2 (GLRX2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, GLRX2 (mGFP-tagged)-Human glutaredoxin 2 (GLRX2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, GLRX2 (Myc-DDK-tagged)-Human glutaredoxin 2 (GLRX2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, GLRX2 (Myc-DDK-tagged)-Human glutaredoxin 2 (GLRX2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Glrx2 (GFP-tagged) - Mouse glutaredoxin 2 (thioltransferase) (Glrx2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Glrx2 (GFP-tagged) - Mouse glutaredoxin 2 (thioltransferase) (Glrx2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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