Glutathione peroxidase 1 / GPX1 antibody

Principal name

Glutathione peroxidase 1 / GPX1 antibody

Alternative names for Glutathione peroxidase 1 / GPX1 antibody

GSHPx-1, Cellular glutathione peroxidase

SwissProt ID

P00435 (Bovin), P04041 (Rat), P07203 (Human), P11352 (Mouse), P11909 (Rabit)

Gene ID

281209 (GPX1), 2876, 14775 (Gpx1), 24404

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Bt (Bat), Can (Canine), Eq (Equine), Hst (Hamster), Mky (Monkey), Por (Porcine), Prim (Primate), Rb (Rabbit), Bear

Available hosts

Sheep, Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Frozen Sections (C)

Background of Glutathione peroxidase 1 / GPX1 antibody

Glutathione peroxidases(GPxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. This protein is one of the most important antioxidant enzymes in humans. This protein has been reported to protect cultured breast cancer cells from CD95-induced apoptosis and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell growth and increases resistance to toxic challenges.
There are several isoforms which differ in their primary structure and localization. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis specific secretory GPx(eGPxor GPx5)isoforms, possess selenocysteine at the active site.
One allele of the Glutathione Peroxidase 1 gene is significantly associated with an increased breast cancer risk.

General readings

Moyer,A.M., et.al., Cancer Epidemiol. Biomarkers Prev. 19 (3): 811-821 (2010)
Akimoto,A.K., et.al., Free Radic. Res. 44 (3); 322-331 (2010)
Cao,C., et.al., J. Biol. Chem. 278 (41): 39609-39614 (2003)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glutathione peroxidase 1 / GPX1 antibody

Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu ICC/IF, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Glutathione peroxidase 1 / GPX1 (C-term) antibody

Immunohistochemistry analysis of human hepatocarcinoma tissue (Formalin-fixed, Paraffin-embedded) using Glutathione peroxidase 1 / GPX1 antibody Cat.-No. AP51937PU-N (C-term), followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of this antibody for IHC; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms F, ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Glutathione peroxidase 1 / GPX1 antibody

AP32027PU-N Glutathione peroxidase 1 / GPX1 Antibody at 0.3 µg/ml staining of Rat Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Glutathione peroxidase 1 / GPX1 (53-67) antibody

AP32028PU-N Glutathione peroxidase 1 / GPX1 Antibody staining of Rat Liver lysate at 0.1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Glutathione peroxidase 1 / GPX1 (Isomer 1) antibody

TA303116 (1µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Por C, E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutathione peroxidase 1 / GPX1 antibody

Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 13B2AF Purified Hu, Ms, Rt E, IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Glutathione peroxidase 1 / GPX1 (N-term) antibody

Western blot analysis of GPX expression in Jurkat (1), Raji (2), HeLa, (3), NIH/3T3 (4) and PC12 (5) using AM26578AF-N. Mouse IgG1 347 Azide Free Hu ICC/IF, WB
0.1 ml / €360.00
  Acris Antibodies GmbH

Glutathione peroxidase 1 / GPX1 antibody

Glutathione peroxidase 1 / GPX1 Sheep IgG AP Bov, Hu E
1 ml / €410.00
  Acris Antibodies GmbH

Glutathione peroxidase 1 / GPX1 antibody

Glutathione peroxidase 1 / GPX1 Sheep IgG Purified Bov, Hu E
1 ml / €400.00
  Acris Antibodies GmbH

Glutathione peroxidase 1 / GPX1 (130-142) antibody

Human Liver (formalin-fixed, paraffin-embedded) stained with GPX1 antibody AP22871PU-N at 3.75 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hst, Hu, Mky, Por, Prim, Rb, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Glutathione peroxidase 1 / GPX1 antibody

Glutathione peroxidase 1 / GPX1 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Glutathione peroxidase 1 / GPX1 antibody

Immunoprecipitation analysis of HL-60 cell lysates. Lane 1 : Input and lane 2 : Precipitates. Mouse IgG1 2A10 Hu IP
0.1 ml / €390.00
  Abnova Taiwan Corp.

Glutathione peroxidase 1 / GPX1 antibody

Immunoprecipitation analysis of HL-60 cell lysate. Lane 1 : Input and lane 2 : Precipitates. Immunoblotting with GPX1 monoclonal antibody, clone 42C9 ( Cat # MAB0731 ) . Mouse IgG1 42C9 Hu IP
0.1 ml / €390.00
  Abnova Taiwan Corp.

Glutathione peroxidase 1 / GPX1 antibody

Immunoblot analysis of cell and tissue lysates. Lane 1 : HL-60 cell lysate. Lane 2 : Mouse Liver tissue lysate. Lane 3 : Rat Liver tissue lysate. Mouse IgG1 13B2AF Ms E, IP, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Glutathione peroxidase 1 / GPX1 antibody

GPX1 polyclonal antibody ( Cat # PAB7049 ) ( 1 µg/ml ) staining of human liver lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CRISPR

Catalog No. Species Donor Vector  

Gpx1 - mouse gene knockout kit via CRISPR

Gpx1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gpx1 - mouse gene knockout kit via CRISPR

Gpx1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gpx1 - mouse gene knockout kit via CRISPR

Gpx1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gpx1 - mouse gene knockout kit via CRISPR

Gpx1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Glutathione peroxidase 1 / GPX1 (1-203, His-tag)

Glutathione peroxidase 1 / GPX1 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

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