Glutathione peroxidase 4 / GPX4 antibody

Principal name

Glutathione peroxidase 4 / GPX4 antibody

Alternative names for Glutathione peroxidase 4 / GPX4 antibody

GPx-4, Phospholipid hydroperoxide glutathione peroxidase mitochondrial

SwissProt ID

O70325, P36968 (Pig), P36969 (Human), P36970, Q9N2J2 (Bovin)

Gene ID

2879 (GPX4), 625249 (Gpx4), 29328

Available reactivities

GP (Guinea Pig), Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Gt (Goat), Hst (Hamster), Mky (Monkey), Op (Opossum), Por (Porcine), Prim (Primate), Ze (Zebrafish)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP)

Background of Glutathione peroxidase 4 / GPX4 antibody

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through altertive splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for altertive splicing exists; altertive transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through altertive splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for altertive splicing exists; altertive transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glutathione peroxidase 4 / GPX4 (Isoform a and c) (C-term) antibody

  Goat Polyclonal Antibody against GPX4  
TA303125 (0.1µg/ml) staining of Human Testis lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Purified Bov, Hu, Ms, Por, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutathione peroxidase 4 / GPX4 antibody

  Rabbit polyclonal Glutathione Peroxidase 4 antibody  
Western blot using affinity purified anti-GPx4 to detect GPx4 in testis extract (arrow). Tissue extract (40 µg) was electrophoresed and transferred to nitrocellulose. The membrane was probed with the primary antibody at a 1:1,000 dilution. Personal Communication, Dolph Hatfield, CCR-NCI, Bethesda, MD. Rabbit IgG Aff - Purified GP, Hu, Ms, Rt E, WB
0.1 mg / €356.00
  OriGene Technologies, Inc.

Glutathione peroxidase 4 / GPX4 antibody

  GPX4 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of mouse kidney cell lines, using GPX4 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutathione peroxidase 4 / GPX4 antibody

  Rabbit Polyclonal Anti-GPX4 Antibody - middle region  
GPX4 antibody - middle region validated by WB using HepG2 cell lysate at 1.0 ug/ml.GPX4 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, GP, Gt, Hu, Ms, Rt, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Glutathione peroxidase 4 / GPX4 (C-term) antibody

Glutathione peroxidase 4 / GPX4 Rabbit IgG Purified GP, Hu, Ms, Rt E, WB
50 µg / €360.00
  Acris Antibodies GmbH

Glutathione peroxidase 4 / GPX4 (184-196) antibody

Human Testis (formalin-fixed, paraffin-embedded) stained with GPX4 antibody AP22541PU-N at 2.5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bov, GP, Gt, Hst, Hu, Mky, Ms, Op, Por, Prim, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Glutathione peroxidase 4 / GPX4 antibody

Glutathione peroxidase 4 / GPX4 Rabbit Serum Hu C, E, F, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

GPX4 - human gene knockout kit via CRISPR

GPX4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GPX4 - human gene knockout kit via CRISPR

GPX4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GPX4 - human gene knockout kit via CRISPR

GPX4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GPX4 - human gene knockout kit via CRISPR

GPX4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gpx4 - mouse gene knockout kit via CRISPR

Gpx4 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gpx4 - mouse gene knockout kit via CRISPR

Gpx4 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gpx4 - mouse gene knockout kit via CRISPR

Gpx4 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gpx4 - mouse gene knockout kit via CRISPR

Gpx4 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GPX4 (mGFP-tagged)-Human glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant 2, (Note, selenocystein protein, internal stop codon, see summary), 200 uL, >10^7 TU/mL

Lenti ORF particles, GPX4 (mGFP-tagged)-Human glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant 2, (Note, selenocystein protein, internal stop codon, see summary), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, GPX4 (mGFP-tagged)-Human glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant 3, (Note, selenocystein protein, internal stop codon, see summary), 200 uL, >10^7 TU/mL

Lenti ORF particles, GPX4 (mGFP-tagged)-Human glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant 3, (Note, selenocystein protein, internal stop codon, see summary), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, GPX4 (Myc-DDK-tagged)-Human glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant 2, (Note, selenocystein protein, internal stop codon, see summary), 200 uL, >10^7 TU/mL

Lenti ORF particles, GPX4 (Myc-DDK-tagged)-Human glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant 2, (Note, selenocystein protein, internal stop codon, see summary), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Lenti ORF particles, GPX4 (Myc-DDK-tagged)-Human glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant 3, (Note, selenocystein protein, internal stop codon, see summary), 200 uL, >10^7 TU/mL

Lenti ORF particles, GPX4 (Myc-DDK-tagged)-Human glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant 3, (Note, selenocystein protein, internal stop codon, see summary), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Dio1 (GFP-tagged) - Mouse deiodinase, iodothyronine, type I (Dio1), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below), 200 uL, >10^7 TU/mL

Lenti ORF particles, Dio1 (GFP-tagged) - Mouse deiodinase, iodothyronine, type I (Dio1), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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