Glutathione peroxidase 4 / GPX4 antibody

Principal name

Glutathione peroxidase 4 / GPX4 antibody

Alternative names for Glutathione peroxidase 4 / GPX4 antibody

GPx-4, Phospholipid hydroperoxide glutathione peroxidase mitochondrial

SwissProt ID

O70325, P36968 (Pig), P36969 (Human), P36970, Q9N2J2 (Bovin)

Gene ID

2879 (GPX4)

Available reactivities

Hu (Human), GP (Guinea Pig), Ms (Mouse), Rt (Rat), Bov (Bovine), Gt (Goat), Hst (Hamster), Mky (Monkey), Op (Opossum), Por (Porcine), Prim (Primate), Ze (Zebrafish)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Flow Cytometry (F), Frozen Sections (C)

Background of Glutathione peroxidase 4 / GPX4 antibody

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.

General readings

Su D, Novoselov SV, Sun QA, Moustafa ME, Zhou Y, Oko R, Hatfield DL, Gladyshev VN. Mammalian selenoprotein thioredoxin/glutathione reductase: Roles in disulfide bond formation and sperm maturation. J Biol Chem. 2005 May 18; [Epub ahead of print] PMID: 15901730

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glutathione peroxidase 4 / GPX4 (Isoform a and c) (C-term) antibody

TA303125 (0.1µg/ml) staining of Human Testis lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Purified Bov, Hu, Ms, Por, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutathione peroxidase 4 / GPX4 antibody

Western blot using affinity purified anti-GPx4 to detect GPx4 in testis extract (arrow). Tissue extract (40 µg) was electrophoresed and transferred to nitrocellulose. The membrane was probed with the primary antibody at a 1:1,000 dilution. Personal Communication, Dolph Hatfield, CCR-NCI, Bethesda, MD. Rabbit IgG Aff - Purified GP, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutathione peroxidase 4 / GPX4 antibody

Western blot analysis of extracts of mouse kidney cell lines, using GPX4 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Glutathione peroxidase 4 / GPX4 antibody

GPX4 antibody - middle region validated by WB using HepG2 cell lysate at 1.0 ug/ml.GPX4 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, GP, Gt, Hu, Ms, Rt, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Glutathione peroxidase 4 / GPX4 (C-term) antibody

Glutathione peroxidase 4 / GPX4 Rabbit IgG Purified GP, Hu, Ms, Rt E, WB
50 µg / €360.00
  Acris Antibodies GmbH

Glutathione peroxidase 4 / GPX4 (184-196) antibody

Human Testis (formalin-fixed, paraffin-embedded) stained with GPX4 antibody AP22541PU-N at 2.5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bov, GP, Gt, Hst, Hu, Mky, Ms, Op, Por, Prim, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Glutathione peroxidase 4 / GPX4 antibody

Glutathione peroxidase 4 / GPX4 Rabbit Serum Hu C, E, F, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Glutathione peroxidase 4 / GPX4 antibody

Glutathione peroxidase 4 / GPX4 Mouse IgG1 7A4 Hu E, IP
0.1 ml / €390.00
  Abnova Taiwan Corp.

Glutathione peroxidase 4 / GPX4 antibody

Immunoprecipitation analysis of HL-60 cell lysates. Lane 1 : Input and lane 2 : Precipitates. Immunoblotting with GPX4 monoclonal antibody, clone 1H11 ( Cat # MAB0729 ). Mouse IgG1 1H11 Hu E, IP
0.1 ml / €390.00
  Abnova Taiwan Corp.

Glutathione peroxidase 4 / GPX4 antibody

GPX4 polyclonal antibody ( Cat # PAB7065 ) ( 0.1 µg/ml ) staining of human testis lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Glutathione peroxidase 4 / GPX4 antibody

Human Heart; Immunohistochemistry with Heart cell lysate tissue at an antibody concentration of 5.0ug/ml using anti-GPX4 antibody (ARP58473_P050); GPX4 antibody - middle region (ARP58473_P050) in Human Heart cells using Immunohistochemistry Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

Glutathione peroxidase 4 / GPX4 antibody

Glutathione peroxidase 4 / GPX4 Mouse IgG2b 565320 Purified Hu, Ms, Rt WB
25 µg / €160.00
  Novus Biologicals Inc.

Glutathione peroxidase 4 / GPX4 antibody

Western Blot: Glutathione Peroxidase 4 Antibody [NB100-2907] - Detection of human GPX4 by Western Blots obtained with platelet subcellular compartments: homogenate (H), cytosolic (Cyto), membrane (Mb) and mitochonria (Mit). Rabbit Serum Hu P, WB
0.2 ml / €400.00
  Novus Biologicals Inc.

Glutathione peroxidase 4 / GPX4 antibody

Immunohistochemistry: Glutathione Peroxidase 4 (Isoform a and c)_x000d_
 Antibody [NB100-41379] -(0.3µg/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining. Goat IgG Aff - Purified Hu E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Glutathione peroxidase 4 / GPX4 antibody

Glutathione peroxidase 4 / GPX4 Mouse IgG1 1H11 Hu, Ms, Rt IP
0.1 mg / €530.00
  Novus Biologicals Inc.

Glutathione peroxidase 4 / GPX4 antibody

Glutathione peroxidase 4 / GPX4 Mouse IgG1 19B12 Hu IP
0.1 mg / €530.00
  Novus Biologicals Inc.

Glutathione peroxidase 4 / GPX4 antibody

Immunohistochemistry-Paraffin: Glutathione Peroxidase 4 Antibody [NBP1-54691] - Human Testis (formalin-fixed, paraffin-embedded) stained with GPX4 antibody at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody LS-D3, alkaline phosphatase-streptavidin and chromogen.  IHC Information: Heart Rabbit Aff - Purified Hu P, WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Glutathione peroxidase 4 / GPX4

Quality Control Testing: 1ug/lane 12% SDS-PAGE Stained with Coomassie Blue. Human
0.5 mg / €380.00
  Abnova Taiwan Corp.

18 Item(s)

per page
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