Glycine amidinotransferase antibody

Principal name

Glycine amidinotransferase antibody

Alternative names for Glycine amidinotransferase antibody

Transamidinase, GATM, AGAT, L-arginine:glycine amidinotransferase

SwissProt ID

P50440 (Human), P50441 (Pig), P50442 (Rat), Q2HJ74 (Bovin), Q9D964 (Mouse)

Gene ID

2628 (GATM), 81660 (Gatm), 67092

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Sh (Sheep), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Glycine amidinotransferase antibody

GATM is a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Schulze A (2003). Mol. Cell. Biochem. 244 (1-2): 143-50.Cullen M.E., Et al. (2006) Circulation 114:I16-I20

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Glycine amidinotransferase antibody

  Rabbit Polyclonal Anti-GATM Antibody  
Host: Rabbit; Target Name: NSUN6; Sample Tissue: Human Fetal Lung; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Glycine amidinotransferase antibody

  GATM mouse monoclonal antibody, clone OTI1C9 (formerly 1C9)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-GATM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503147) Mouse IgG1 OTI1C9 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Glycine amidinotransferase antibody

  GATM mouse monoclonal antibody, clone OTI1E3 (formerly 1E3)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-GATM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503207) Mouse IgG2a OTI1E3 Purified Hu F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Glycine amidinotransferase (N-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with Glycine amidinotransferase antibody (N-term) Cat.-No AP51788PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Gatm - mouse gene knockout kit via CRISPR

Gatm - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Glycine amidinotransferase

  Recombinant protein of human glycine amidinotransferase (L-arginine:glycine amidinotransferase) (GATM), nuclear gene encoding mitochondrial protein  
Glycine amidinotransferase Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Glycine amidinotransferase (38-423, His-tag)

Glycine amidinotransferase Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

Glycine amidinotransferase (38-423, His-tag)

Glycine amidinotransferase Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gatm (GFP-tagged ORF) - Rat glycine amidinotransferase (L-arginine:glycine amidinotransferase) (Gatm), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL

Lenti ORF particles, Gatm (GFP-tagged ORF) - Rat glycine amidinotransferase (L-arginine:glycine amidinotransferase) (Gatm), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gatm (Myc-DDK-tagged ORF) - Rat glycine amidinotransferase (L-arginine:glycine amidinotransferase) (Gatm), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL

Lenti ORF particles, Gatm (Myc-DDK-tagged ORF) - Rat glycine amidinotransferase (L-arginine:glycine amidinotransferase) (Gatm), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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