Glycine decarboxylase antibody

Principal name

Glycine decarboxylase antibody

Alternative names for Glycine decarboxylase antibody

Glycine cleavage system P protein, GLDC, Glycine dehydrogenase, GCSP

SwissProt ID

Q2M2F8 (Human)

Gene ID

2731 (GLDC)

Ncbi ID

9606, NP_000161

Available reactivities

Hu (Human)

Available hosts

Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of Glycine decarboxylase antibody

The enzyme system for cleavage of glycine (glycine cleavage system; GCS; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes; see MIM 238310, MIM 238330, and MIM 238331.[supplied by OMIM]

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