Glypican-1 / GPC1 antibody
Principal name
Glypican-1 / GPC1 antibody
Ncbi ID
9606, NP_002072.2, NP_002072, NM_002081, NP_057905.1, NM_016696, NM_030828
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C)
Background of Glypican-1 / GPC1 antibody
Glypican-1 (also known as GPC1 or FLJ38078) is a member of the glypican-related integral membrane proteoglycan family (GRIPS). This protein is a heparan sulfate proteoglycan which is composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains and are anchored to the cell surface via a covalent linkage to glycosylphosphatidlyinositol (GPI). Glypicans can modify cell signaling pathways and contribute to cellular proliferation and tissue growth. In humans, glypican-1 is over expressed in breast and brain cancers (gliomas). All glypicans contain an N-terminal signal peptide and a hydrophobic domain in their C-terminal region which is required for attachment of the GPI anchor. The amino acid sequences of the six vertebrate glypican family members vary from 17% to 63% identity. The location of 14 cysteine amino acids is conserved between the glypicans, suggesting the existence of a highly similar three-dimensional structure. Heparan sulfate glycosaminoglycan chains are attached at the 50 amino acids at the C-terminal end of the protein, near the anchor and the cell membrane. Glypican functions as coreceptor for a variety of growth factors. Glypican-1 has been shown to interact with SLIT2.
General readings
Sjoeblom T., et.al., Science 314:268-274(2006)





Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA319424 | Glypican-1 / GPC1 antibody |
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Rabbit polyclonal Glypican-1 antibody | |||||||
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Rabbit | IgG | Aff - Purified | Can, Hu, Macaque, Ms, Op, Rt | E, WB |
0.1 mg /
€503.00
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OriGene Technologies, Inc. | |||||||
AM31485AF-N | Glypican-1 / GPC1 antibody |
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Mouse | IgG1 | B485M | Azide Free | Hu | E, ICC/IF, WB |
0.1 mg /
€630.00
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Acris Antibodies GmbH | |||||||
AP51865PU-N | Glypican-1 / GPC1 (N-term) antibody |
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Rabbit | Ig | Purified | Hu | F, P, WB |
0.4 ml /
€370.00
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Acris Antibodies GmbH | |||||||
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AP54982SU-N | Glypican-1 / GPC1 antibody |
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Rabbit | Serum | Hu | C, E, WB |
0.2 ml /
€400.00
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Acris Antibodies GmbH |
CRISPR
Catalog No. | Species | Donor Vector | |
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KN307154 | Gpc1 - mouse gene knockout kit via CRISPR |
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Mouse | GFP-Puro |
1 kit /
€1,290.00
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OriGene Technologies, Inc. | |||
KN307154BN | Gpc1 - mouse gene knockout kit via CRISPR |
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Mouse | mBFP-Neo |
1 kit /
€1,290.00
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OriGene Technologies, Inc. | |||
KN307154LP | Gpc1 - mouse gene knockout kit via CRISPR |
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Mouse | Luciferase-Puro |
1 kit /
€1,290.00
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OriGene Technologies, Inc. | |||
KN307154RB | Gpc1 - mouse gene knockout kit via CRISPR |
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Mouse | RFP-BSD |
1 kit /
€1,290.00
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OriGene Technologies, Inc. |
Human Lenti ORF Particles
Catalog No. | ||
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RC208602L2V | Lenti ORF particles, GPC1 (mGFP-tagged) - Human glypican 1 (GPC1), 200 uL, >10^7 TU/mL |
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200 µl /
€1,082.00
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OriGene Technologies, Inc. | ||
RC208602L1V | Lenti ORF particles, GPC1 (Myc-DDK tagged) - Human glypican 1 (GPC1) , 200 uL, >10^7 TU/mL |
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200 µl /
€969.00
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OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
Catalog No. | ||
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MR208830L2V | Lenti ORF particles, Gpc1 (GFP-tagged) - Mouse glypican 1 (Gpc1), 200 uL, >10^7 TU/mL |
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200 µl /
€1,226.00
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OriGene Technologies, Inc. | ||
MR208830L1V | Lenti ORF particles, Gpc1 (Myc-DDK-tagged) - Mouse glypican 1 (Gpc1), 200 uL, >10^7 TU/mL |
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200 µl /
€1,103.00
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OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
Catalog No. | ||
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RR207143L2V | Lenti ORF particles, Gpc1 (GFP-tagged ORF) - Rat glypican 1 (Gpc1), 200 uL, >10^7 TU/mL |
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200 µl /
€1,236.00
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OriGene Technologies, Inc. | ||
RR207143L1V | Lenti ORF particles, Gpc1 (Myc-DDK-tagged ORF) - Rat glypican 1 (Gpc1), 200 uL, >10^7 TU/mL |
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200 µl /
€1,104.00
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OriGene Technologies, Inc. | ||