GMDS antibody

Principal name

GMDS antibody

Alternative names for GMDS antibody

GDP-D-mannose dehydratase, GMD, GDP-mannose 4,6 dehydratase

SwissProt ID

O60547 (Human), Q8K0C9 (Mouse), Q8K3X3 (Crigr)

Gene ID

2762 (GMDS)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP), ELISA (detection) (E(detection))

Background of GMDS antibody

GMD is a 372 amino acid protein that utilizes NADP as a cofactor to catalyze the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose. GMD mutations are involved in resistance to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis. The gene encoding GMD maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

General readings

Ohyama C. et al. (1998) J Biol Chem. 273: 14582-14587.Moriwaki K. et al. (2009) Gastroenterology 137: 188-198.

13 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GMDS antibody

Sample (30 ug of whole cell lysate). A: A431 . B: H1299. 10% SDS PAGE. TA308887 diluted at 1:1000. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GMDS antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GMDS (RC200471, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GMDS. Mouse IgG2a OTI2A1 Purified Hu WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

GMDS antibody

GMDS Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

GMDS antibody

GMDS Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

GMDS antibody

Western  Blot:  GMDS Antibody [NBP1-33424] – Western blot analysis of GMDS on A431 (Lane A) and H1299 (Lane B) lysates using NBP1-33424 at a dilution of 1:1000. 30ug whole cell lysate loaded on 10% SDS PAGE gel. Rabbit IgG Hu P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

GMDS antibody

Immunohistochemistry-Paraffin: GMDS Antibody [NBP1-83357] Immunohistochemical staining of human rectum shows strong cytoplasmic and nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GMDS

GMDS Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

GMDS (1-372, His-tag)

GMDS Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

GMDS (1-372, His-tag)

GMDS Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

GMDS (1-496, His-tag)

GMDS Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

GMDS (1-496, His-tag)

GMDS Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

GMDS

GMDS Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

GMDS

GMDS Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

13 Item(s)

per page
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