GMEB2 antibody

Principal name

GMEB2 antibody

Alternative names for GMEB2 antibody

GMEB-2, p79PIF, PIF-p79, Glucocorticoid modulatory element-binding protein 2, Parvovirus initiation factor p79, DNA-binding protein p79PIF

SwissProt ID

O88873 (Rat), P58929 (Mouse), Q9UKD1 (Human)

Gene ID

26205 (GMEB2)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), GP (Guinea Pig), Rb (Rabbit), Eq (Equine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of GMEB2 antibody

GMEB-2 is a DNA-binding protein that plays a crucial role modulating transcription upon activation by steroid hormones. GMEB-2 is ubiquitously expressed with preferential expression in developmentally important tissues, such as testis, bone marrow, placenta and fetal tissues. It localizes to the nucleus and cytoplasm and contains a SAND domain near its N-terminus and a C-terminal coiled coil structure. GMEB-2 functions as a homodimer or as a heterodimer with GMEB-1. The formed complex specifically binds to glucocorticoid modulatory elements (GME) in the promoter region of target genes and recruits the histone acetylase CREB binding protein (CBP) during glucocorticoid signaling. This acts to increase sensitivity to low concentrations of glucocorticoids. In addition, GMEB-2 functions as an auxiliary factor required for parvovirus replication.

General readings

Burnett,E., (2001) J. Mol. Biol. 314 (5), 1029-1039

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GMEB2 antibody

WB Suggested Anti-GMEB2 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 312500; Positive Control: HepG2 cell lysate; GMEB2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GMEB2 antibody

GMEB2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

GMEB2 antibody

Human kidney; GMEB2 antibody - C-terminal region (ARP38990_T100) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

GMEB2 antibody

Immunohistochemistry-Paraffin: GMEB2 Antibody [NBP1-81421] - Immunohistochemistry-Paraffin: GMEB2 Antibody [NBP1-81421] Immunohistochemical staining of human thyroid gland shows strong nuclear and cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GMEB2

GMEB2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

GMEB2

GMEB2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

GMEB2

GMEB2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GMEB2 overexpression lysate

GMEB2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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