GnRH Receptor / GNRHR antibody

Principal name

GnRH Receptor / GNRHR antibody

Alternative names for GnRH Receptor / GNRHR antibody

Gonadotropin-releasing hormone receptor, GnRH-R, GRHR

SwissProt ID

O18821 (Horse), P30968 (Human), P30969 (Rat), P32236 (Bovin), P32237 (Sheep), P49922 (Pig), Q01776 (Mouse), Q8CH60 (Cavpo)

Gene ID

2798 (GNRHR), 81668 (Gnrhr), 14715

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bt (Bat), Bov (Bovine), Can (Canine), Eq (Equine), Op (Opossum), Por (Porcine), Prim (Primate), Rb (Rabbit), Sh (Sheep), Bear

Available hosts

Mouse, Goat, Rabbit

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of GnRH Receptor / GNRHR antibody

Godotropin-releasing hormone (GnRH) or Luteinizing hormone releasing hormone (LHRH) is a decapeptide synthesized and released from neurons in the hypothalamus and stimulates the synthesis and release of godotropin hormone (or luteinizing hormone) and follicle stimulating hormone from the pituitary gland. GnRH is expressed as various variants, and most vertebrates express more than one form of GnRH. GnRH and its variants bind and activate GnRH receptor (GnRHR), a member of the G-protein coupled receptor (GPCR) superfamily. Three forms of the receptor have been identified in vertebrates (types I, II and III). Like all members, GnRHR has seven transmembrane domains and an extracellular N-terminus and an intracellular C-termil tail. The receptor also has a number of glycosylation sites in its extracellular loops. In addition, the C-termil tail is unusually short and lacks consensus sites known to undergo post-translatiol modifications like phosphorylation. In consequence, this affects the receptor’s desensitization and interlization. Expression of GnRHR is detected in the godotrope and various tissues like breast, gods, prostate and uterus.

General readings

Yeung CM, An BS, Cheng CK, Chow BK, Leung PC.
Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells.
Mol Hum Reprod. 2005 Nov;11(11):837-42. Epub 2005 Dec 19.
PMID: 16364974

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GnRH Receptor / GNRHR antibody

  Goat Polyclonal Antibody against GRHR / LRHR  
TA302503 (0.5µg/ml) staining of Human Peripheral Blood Mononucleocyte lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GnRH Receptor / GNRHR antibody

  Mouse anti-GnRHR monoclonal antibody  
Western blot analysis of the molecular weight and levels of gonadotropin-releasing hormone (GnRH) receptor protein. Lanes 1 and 2: tissue extracts from different stages of ovarian cancers. Lane M: protein makders, molecular weight in kDa. Mouse IgG AT2.G7 Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GnRH Receptor / GNRHR antibody

  Anti-GNRHR Rabbit Polyclonal Antibody  
Predicted band size: 28 kDa . Positive control: 231 cell and mouse testis tissue lysate. Recommended dilution: 1/1000-2000. (Gel: 10%SDS-PAGE Lane1: 231 cell lysate Lane2: Mouse testis tissue lysate Lysates: 40 ug per lane Primary antibody: 1/650 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 7 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GnRH Receptor / GNRHR antibody

  Anti-GNRHR Rabbit Polyclonal Antibody  
Gel: 10%SDS-PAGE, Lysate: 40 µg, Lane 1-2: 231 cells, mouse testis tissue, Primary antibody: GNRHR Antibody at dilution 1/2350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 25 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GnRH Receptor / GNRHR antibody

  Rabbit Polyclonal Anti-GnRH Receptor (extracellular)  
Western blot analysis of rat ovary (lanes 1 and 3) and rat pituitary (lanes 2 and 4) lysates: 1, 2. Anti-GnRH Receptor (extracellular) antibody, (1:200). 3, 4. Anti-GnRH Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

GnRH Receptor / GNRHR (3rd cytopl. dom.) antibody

  Rabbit Polyclonal Anti-GNRHR Antibody (Cytoplasmic Domain)  
Anti-GNRHR antibody IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hu, Ms, Op, Por, Prim, Rb, Rt, Sh P
50 µg / €400.00
  OriGene Technologies, Inc.

GnRH Receptor / GNRHR antibody

GnRH Receptor / GNRHR Mouse IgG1 F1G4 Purified Hu C, E, WB
0.1 mg / €310.00
  Acris Antibodies GmbH

GnRH Receptor / GNRHR antibody

GnRH Receptor / GNRHR Mouse IgG1 A9E4 Purified Hu C, E, F, WB
0.2 mg / €360.00
  Acris Antibodies GmbH

GnRH Receptor / GNRHR antibody

GnRH Receptor / GNRHR Mouse IgG1 A9E4 Purified Hu C, E, WB
0.1 mg / €310.00
  Acris Antibodies GmbH

GnRH Receptor / GNRHR antibody

Immunofluorescence analysis of A549 cells, using GNRHR Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF
50 µg / €230.00
  Assay Biotech

GnRH Receptor / GNRHR antibody

Immunofluorescence analysis of A549 cells, using GNRHR Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

GNRHR - human gene knockout kit via CRISPR

GNRHR - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GNRHR - human gene knockout kit via CRISPR

GNRHR - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GNRHR - human gene knockout kit via CRISPR

GNRHR - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GNRHR - human gene knockout kit via CRISPR

GNRHR - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gnrhr - mouse gene knockout kit via CRISPR

Gnrhr - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gnrhr - mouse gene knockout kit via CRISPR

Gnrhr - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gnrhr - mouse gene knockout kit via CRISPR

Gnrhr - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gnrhr - mouse gene knockout kit via CRISPR

Gnrhr - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

GNRHR overexpression lysate

GNRHR overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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