GNRH2 / Progonadoliberin-2 antibody

Principal name

GNRH2 / Progonadoliberin-2 antibody

SwissProt ID

O43555 (Human), P68072 (Chick)

Gene ID

2797 (GNRH2)

Available reactivities

Hu (Human)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of GNRH2 / Progonadoliberin-2 antibody

Human reproduction is controlled by the hypothalaic-pituitary gonadal axis laid down early in fetal development. Gonadotropin releasing hormone (GnRH), also known as GnRH-associated peptide, luteinizing hormone releasing hormone (LHRH), luliberin or gonadorelin, is a decapeptide that is an important molecule in the hypothalamic-pituitary-gonadal axis control circuit. GnRH is produced by hypothalamic neurons and secreted in a pulsatile manner into the capillary plexus of the medianeminence. GnRH affects the release of lutenizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary. In addition to hypothalamic GnRH (GnRH I), a second GnRH form (GnRH II) functions primarily in the midbrain. GnRH is expressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells. Unlike GnRH I, GnRH II is highly expressed outside the brain, particularly in the kidney, bone marrow and prostate, suggesting that it may have multiple functions. GnRH binds to a specific G protein-coupled receptor in the pituitary to regulate synthesis and secretion of gonadotropins.

General readings

Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Poon, S.L., et al. Mol. Endocrinol. 23(10):1646-1656(2009)
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009)
Palmieri, R.T., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3567-3572(2008)
Poon, S.L., et al. Endocrinology 149(10):5162-5171(2008)

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GNRH2 / Progonadoliberin-2 (Center) antibody

Western blot analysis of GNRH2 Antibody (Center) Cat.-No AP51886PU-N in MDA-MB435 cell line lysates (35ug/lane). GNRH2 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GNRH2 / Progonadoliberin-2 antibody

GNRH2 / Progonadoliberin-2 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

GNRH2 / Progonadoliberin-2 antibody

Immunohistochemistry-Paraffin: GNRH2 Antibody [NBP1-86515] - Immunohistochemistry-Paraffin: GNRH2 Antibody [NBP1-86515] Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GNRH2 / Progonadoliberin-2 (transcript variant 1)

GNRH2 / Progonadoliberin-2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

GNRH2 / Progonadoliberin-2

GNRH2 / Progonadoliberin-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

GNRH2 / Progonadoliberin-2

GNRH2 / Progonadoliberin-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GNRH2 overexpression lysate

GNRH2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

GNRH2 overexpression lysate

GNRH2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

GNRH2 overexpression lysate

GNRH2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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