GPR109A antibody

Principal name

GPR109A antibody

Alternative names for GPR109A antibody

HM74A, NIACR1, Niacin receptor 1, Nicotinic acid receptor, PUMA-G, Pumag, G-protein coupled receptor 109A, G-protein coupled receptor HM74A

SwissProt ID

Q80Z39 (Rat), Q8TDS4 (Human), Q9EP66 (Mouse)

Gene ID

338442 (HCAR2), 80885 (Niacr1), 353250

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of GPR109A antibody

NIACR1 acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide

10 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GPR109A antibody

GPR109A Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

GPR109A (Center) antibody

Western blot analysis of GPR109A Antibody (Center) Cat.-No AP52875PU-N in NCI-H292 cell line lysates (35ug/lane). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GPR109A

GPR109A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

HCAR2 overexpression lysate

HCAR2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, HCAR2 (mGFP-tagged) - Human G protein-coupled receptor 109A (GPR109A), 200 uL, >10^7 TU/mL

Lenti ORF particles, HCAR2 (mGFP-tagged) - Human G protein-coupled receptor 109A (GPR109A), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, HCAR2 (Myc-DDK tagged) - Human G protein-coupled receptor 109A (GPR109A) , 200 uL, >10^7 TU/mL

Lenti ORF particles, HCAR2 (Myc-DDK tagged) - Human G protein-coupled receptor 109A (GPR109A) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Niacr1 (GFP-tagged) - Mouse niacin receptor 1 (Niacr1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Niacr1 (GFP-tagged) - Mouse niacin receptor 1 (Niacr1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Niacr1 (Myc-DDK-tagged) - Mouse niacin receptor 1 (Niacr1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Niacr1 (Myc-DDK-tagged) - Mouse niacin receptor 1 (Niacr1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Niacr1 (GFP-tagged ORF) - Rat niacin receptor 1 (Niacr1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Niacr1 (GFP-tagged ORF) - Rat niacin receptor 1 (Niacr1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Niacr1 (Myc-DDK-tagged ORF) - Rat niacin receptor 1 (Niacr1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Niacr1 (Myc-DDK-tagged ORF) - Rat niacin receptor 1 (Niacr1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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