GPR119 antibody

Principal name

GPR119 antibody

Alternative names for GPR119 antibody

G-protein coupled receptor 119, Glucose-dependent insulinotropic receptor

SwissProt ID

Q7TQN8 (Rat), Q7TQP3 (Mouse), Q8TDV5 (Human)

Gene ID

139760 (GPR119), 236781 (Gpr119), 302813

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), Hst (Hamster), Mky (Monkey), Rb (Rabbit), Gorilla

Available hosts

Rabbit, Goat

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of GPR119 antibody

G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intra cellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane- spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR119 is a 335 amino acid protein that is mainly expressed in the pancreas. It is an endogenous receptor for lysophosphatidylcholine (LPC), which is is a lipid mediator involved in insulin secretion from pancreatic cells. GPR119 may participate in this insulin secretion, suggesting that it may be potential target for new anti-diabetic drugs.

General readings

Sakamoto Y. et al. Expression and distribution of Grp119 in the pancreatic islets of mice and rats : Predominant localization in pancreatic polypeptide-secreting PP-cellsBiochem Biophys Res Commun. 2006 Dec 15;351(2):474-80. Epub 2006 Oct 24.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GPR119 (C-term) antibody

  Goat Polyclonal Antibody against GPR119  
TA302500 (0.3µg/ml) staining of Human Ovary lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GPR119 antibody

  Rabbit polyclonal anti-GPR119 antibody  
Western blot analysis of extracts from K562 cells, using GPR119 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GPR119 antibody

  GPR119 Rabbit Polyclonal (Cytoplasmic Domain) Antibody  
GPR119 Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

GPR119 antibody

  GPR119 Rabbit Polyclonal (Cytoplasmic Domain) Antibody  
Anti-GPR119 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Can, Eq, Gorilla, Hst, Hu, Mky, Ms, Rb, Rt
50 µg / €400.00
  OriGene Technologies, Inc.

GPR119 antibody

Western Blotting of GPR119 using antibody cat.no. AP01207PU-N at 1:500 dilution.Lane 1: HEK293T whole cell lysateLane 2: sp2/0 whole cell lysateLane 3: Rat brain tisue lysate Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GPR119 antibody

GPR119 Rabbit Serum Ms C, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

GPR119 antibody

GPR119 Rabbit Serum Ms, Rt C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

GPR119 antibody

Immunohistochemical staining of Pancreas using anti- GPR119 antibody SP4186P Rabbit Aff - Purified Hu P
50 µg / €470.00
  Acris Antibodies GmbH

GPR119 antibody

Immunofluorescence analysis of MCF7 cells, using GPR119 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

GPR119 antibody

Immunofluorescence analysis of MCF7 cells, using GPR119 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Gpr119 - mouse gene knockout kit via CRISPR

Gpr119 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gpr119 - mouse gene knockout kit via CRISPR

Gpr119 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gpr119 - mouse gene knockout kit via CRISPR

Gpr119 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gpr119 - mouse gene knockout kit via CRISPR

Gpr119 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

GPR119 overexpression lysate

GPR119 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GPR119 (mGFP-tagged) - Human G protein-coupled receptor 119 (GPR119), 200 uL, >10^7 TU/mL

Lenti ORF particles, GPR119 (mGFP-tagged) - Human G protein-coupled receptor 119 (GPR119), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, GPR119 (Myc-DDK tagged) - Human G protein-coupled receptor 119 (GPR119) , 200 uL, >10^7 TU/mL

Lenti ORF particles, GPR119 (Myc-DDK tagged) - Human G protein-coupled receptor 119 (GPR119) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gpr119 (GFP-tagged) - Mouse G-protein coupled receptor 119 (Gpr119), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gpr119 (GFP-tagged) - Mouse G-protein coupled receptor 119 (Gpr119), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gpr119 (Myc-DDK-tagged) - Mouse G-protein coupled receptor 119 (Gpr119), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gpr119 (Myc-DDK-tagged) - Mouse G-protein coupled receptor 119 (Gpr119), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gpr119 (GFP-tagged ORF) - Rat G protein-coupled receptor 119 (Gpr119), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gpr119 (GFP-tagged ORF) - Rat G protein-coupled receptor 119 (Gpr119), 200 uL, >10^7 TU/mL  
200 µl / €1,080.00
  OriGene Technologies, Inc.

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