GPR125 antibody

Principal name

GPR125 antibody

Alternative names for GPR125 antibody

Probable G-protein coupled receptor 125

SwissProt ID

Q7TT36 (Mouse), Q8IWK6 (Human)

Gene ID

166647 (GPR125)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of GPR125 antibody

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and the LN-TM7 subfamily. Considered a novel orphan adhesion-type G-protein-coupled receptor, GPR125 has five leucine rich repeats (LRR), an immunoglobulin (Ig) domain and a GPS domain. GPR125 may play a functional role in choroidal and hippocampal response to brain injury. It is also suggested that GPR125 may be a marker for spermatogonial stem cells. Four isoforms of GPR125 exists due to alternative splicing events.

General readings

Seandel M, James D, Shmelkov SV, Falciatori I, Kim J, Chavala S, Scherr DS, Zhang F, Torres R, Gale NW, Yancopoulos GD, Murphy A, Valenzuela DM, Hobbs RM, Pandolfi PP, Rafii S.
Generation of functional multipotent adult stem cells from GPR125+ germline progenitors.
Nature. 2007 Sep 20;449(7160):346-50.
PMID: 17882221

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GPR125 antibody

  Goat Anti-GPR125 Antibody  
TA305855 (0.5ug/ml) staining of Human Ovary lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GPR125 antibody

  Rabbit Polyclonal GPR125 Antibody  
ELISA: GPCR GPR125 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GPR125 (mGFP-tagged)-Human G protein-coupled receptor 125 (GPR125), 200 uL, >10^7 TU/mL

Lenti ORF particles, GPR125 (mGFP-tagged)-Human G protein-coupled receptor 125 (GPR125), 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, GPR125 (Myc-DDK-tagged)-Human G protein-coupled receptor 125 (GPR125), 200 uL, >10^7 TU/mL

Lenti ORF particles, GPR125 (Myc-DDK-tagged)-Human G protein-coupled receptor 125 (GPR125), 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gpr125 (GFP-tagged) - Mouse G protein-coupled receptor 125 (Gpr125), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gpr125 (GFP-tagged) - Mouse G protein-coupled receptor 125 (Gpr125), 200 uL, >10^7 TU/mL  
200 µl / €2,180.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gpr125 (Myc-DDK-tagged) - Mouse G protein-coupled receptor 125 (Gpr125), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gpr125 (Myc-DDK-tagged) - Mouse G protein-coupled receptor 125 (Gpr125), 200 uL, >10^7 TU/mL  
200 µl / €1,970.00
  OriGene Technologies, Inc.

6 Item(s)

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