GPR132 / G2A antibody
Principal name
GPR132 / G2A antibody
Alternative names for GPR132 / G2A antibody
G-protein coupled receptor 132, G2 accumulation protein
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB)
Background of GPR132 / G2A antibody
G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress. G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, and it is more highly detected in pro-B cells, while lower expression is observed in immature B cells and pre-B cells. G2A is expressed throughout T cell maturation, and it is further increased in response to T-cell activation. Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition. G2A is also able to attenuate the proliferative effects of Bcr-Abl, a chimeric tyrosine kinase oncogene, suggesting that G2A possesses anti-oncogenic properties. The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, where it is required for ubiquitination and proteolytic degradation.
Human Spleen (formalin-fixed, paraffin-embedded) stained with GPR132 antibody AP06923PU-N at 12 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
Western blot (WB) analysis of G2A antibody (Cat.-No. AP01208PU-N) in extracts from COS-7 cells.
Western blot (WB) analysis of G2A antibody (Cat.-No. AP01208PU-N) at 1/500 dilution Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
Human Tonsil (formalin-fixed, paraffin-embedded) stained with GPR132 antibody AP22835PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
Human Spleen (formalin-fixed, paraffin-embedded) stained with GPR132 antibody AP22835PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
Western blot analysis of GPR132 expression in U251MG (A); U2OS (B) whole cell lysates.
Western blot analysis of extracts from COS-7 cells, using GPR132 antibody.The lane on the right is treated with the synthesized peptide.
Anti-GPR132 / G2A antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR132 / G2A antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR132 / G2A antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR132 / G2A antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR132 / G2A antibody IHC of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR132 / G2A antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA315403 | GPR132 / G2A antibody |
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| Rabbit polyclonal anti-GPR132 antibody | |||||||
 |
Rabbit | IgG | Purified |
0.1 ml /
€335.00
|
|||
| OriGene Technologies, Inc. | |||||||
| TA340609 | GPR132 / G2A (2nd cytopl. dom.) antibody |
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| Rabbit Polyclonal Anti-GPR132 Antibody (Cytoplasmic Domain) | |||||||
 |
Rabbit | Aff - Purified | Hu, Mky, Prim | P |
50 µg /
€400.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA340669 | GPR132 / G2A (3rd Extracel. Dom.) antibody |
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| Rabbit Polyclonal Anti-GPR132 Antibody (Extracellular Domain) | |||||||
|
Rabbit | Aff - Purified | Hu, Mky, Prim | P |
50 µg /
€400.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA340829 | GPR132 / G2A antibody |
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| Rabbit Polyclonal Anti-GPR132 Antibody (C-Terminus) | |||||||
 |
Rabbit | Purified | Hu, Mky |
50 µg /
€400.00
|
|||
| OriGene Technologies, Inc. | |||||||
 +1 additional image |
|||||||
| AP01208PU-N | GPR132 / G2A antibody |
||||||
 |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, WB |
0.1 mg /
€350.00
|
||
| Acris Antibodies GmbH | |||||||
| +1 additional image |
|||||||
| AP06923PU-N | GPR132 / G2A (C-term) antibody |
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 |
Rabbit | Aff - Purified | Hu | E, P |
50 µg /
€380.00
|
||
| Acris Antibodies GmbH | |||||||
| AP22835PU-N | GPR132 / G2A (internal region) antibody |
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 |
Rabbit | Aff - Purified | Hu | E, P |
50 µg /
€380.00
|
||
| Acris Antibodies GmbH | |||||||
| +1 additional image |
|||||||
| G130-1 | GPR132 / G2A antibody |
||||||
 |
Rabbit | Aff - Purified | Hu, Ms | E, WB |
50 µg /
€230.00
|
||
| Assay Biotech | |||||||
| G130-2 | GPR132 / G2A antibody |
||||||
|
Rabbit | Aff - Purified | Hu, Ms | E, WB |
0.1 mg /
€330.00
|
||
| Assay Biotech | |||||||
| G291-1 | GPR132 / G2A antibody |
||||||
 |
Rabbit | Aff - Purified | Hu | E, WB |
50 µg /
€230.00
|
||
| Assay Biotech | |||||||
| G291-2 | GPR132 / G2A antibody |
||||||
|
Rabbit | Aff - Purified | Hu | E, WB |
0.1 mg /
€330.00
|
||
| Assay Biotech | |||||||
CRISPR
| Catalog No. | Species | Donor Vector | |
|---|---|---|---|
| KN210284 | GPR132 - human gene knockout kit via CRISPR |
||
|
Human | GFP-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN210284BN | GPR132 - human gene knockout kit via CRISPR |
||
|
Human | mBFP-Neo |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN210284LP | GPR132 - human gene knockout kit via CRISPR |
||
|
Human | Luciferase-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN210284RB | GPR132 - human gene knockout kit via CRISPR |
||
|
Human | RFP-BSD |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN307195 | Gpr132 - mouse gene knockout kit via CRISPR |
||
|
Mouse | GFP-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN307195BN | Gpr132 - mouse gene knockout kit via CRISPR |
||
|
Mouse | mBFP-Neo |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN307195LP | Gpr132 - mouse gene knockout kit via CRISPR |
||
|
Mouse | Luciferase-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN307195RB | Gpr132 - mouse gene knockout kit via CRISPR |
||
|
Mouse | RFP-BSD |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC210284L2V | Lenti ORF particles, GPR132 (mGFP-tagged) - Human G protein-coupled receptor 132 (GPR132), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,082.00
|
|
| OriGene Technologies, Inc. | ||
