GPR17 antibody

Principal name

GPR17 antibody

Alternative names for GPR17 antibody

UDP/CysLT receptor, G-protein coupled receptor 17, P2Y-like receptor, R12, Uracil nucleotide/cysteinyl leukotriene receptor

SwissProt ID

Q09QM4 (Rat), Q13304 (Human), Q6NS65 (Mouse)

Gene ID

2840 (GPR17)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Mky (Monkey)

Available hosts

Rabbit, Goat

Available applications

Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F)

Background of GPR17 antibody

G protein-coupled receptor 17, GPR17, also known as uracil nucleotide/cysteinyl leukotriene receptor or P2Y-like receptor (P2YL), is a 367 amino acid member of the G-protein coupled receptor 1 family of proteins. While GPR17 is expressed in kidney, heart and umbilical vein endothelial cells, it is expressed in the highest levels in the brain. Upon brain injury, the extracellular concentrations of nucleotides and cysteinyl leukotrienes (CysLTs), two families of endogenous signaling molecules, increase significantly at the site of damage. In some neurons, GPR17, a membrane receptor for uracil nucleotide and CysLTs, is upregulated as well, infiltrating the lesioned area. GPR17 is thought to play a role in mediating neuronal death, remodeling brain circuitries by microglia and initiating remyelination in damaged neurons. Two named isoforms of GPR17 exist as a result of alternative splicing events.

General readings

Pugliese, A.M., et al. Am. J. Physiol., Cell Physiol. 297 (4), C1028-C1040 (2009)
Parravicini, C., et al. BMC Bioinformatics 9, 263 (2008)
Ciana, P., et al. EMBO J. 25(19):4615-4627 (2006)

  1. Quick-Filters:
  2. Highly Validated (1)

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GPR17 antibody

Anti-GPR17 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

GPR17 antibody

(0.1ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GPR17 antibody

Immunofluorescence analysis of HeLa cells, using GPR17 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

GPR17 antibody

Western blot analysis of extracts from LOVO cells, using GPR17 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GPR17 antibody

Anti-GPR17 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu ICC/IF, P
50 µg / €379.00
  OriGene Technologies, Inc.

GPR17 (Center) antibody

Immunohistochemistry analysis in brain tissue (formalin-fixed, paraffin-embedded) using GPR17 antibody Cat.-No. AP51923PU-N, followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GPR17 antibody  for IHC. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GPR17 (N-term) antibody

Immunohistochemical staining of Brain (Neurons and glia) using anti-GPR17 antibody SP4195P Rabbit Aff - Purified Hu, Prim ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

GPR17 antibody

Immunofluorescence analysis of HeLa cells, using GPR17 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €205.00
  Assay Biotech

GPR17 antibody

Immunofluorescence analysis of HeLa cells, using GPR17 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

GPR17 antibody

Western blot analysis of extracts from LOVO cells, using GPR17 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

GPR17 antibody

Western blot analysis of extracts from LOVO cells, using GPR17 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

GPR17 antibody

Western blot analysis of GPR17 expression in HEK293T (A); Jurkat (B); NIH3T3 (C); rat kidney (D) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

GPR17 antibody

Western blot analysis of GPR17 expression in HEK293T (A); Jurkat (B); NIH3T3 (C); rat kidney (D) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

GPR17 antibody

Western blot analysis of GPR17 expression in HEK293T (A); Jurkat (B); NIH3T3 (C); rat kidney (D) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

GPR17 antibody

GPR17 Goat Aff - Purified Bov, Hu, Ms, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

GPR17 antibody

G Protein Coupled Receptor GPR17 detection using NLS 4229 on human brain (neurons and glia). Rabbit Aff - Purified Hu P
50 µl / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GPR17

GPR17 Human
2 µg / €450.00
  Abnova Taiwan Corp.

GPR17

GPR17 Human
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GPR17 overexpression lysate

GPR17 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

GPR17 overexpression lysate

GPR17 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

per page
  • LinkedIn