GPR37 / PAEL Receptor antibody

Principal name

GPR37 / PAEL Receptor antibody

Alternative names for GPR37 / PAEL Receptor antibody

G-protein coupled receptor 37, PAELR, ETBR-LP-1, Endothelin B receptor-like protein 1, Parkin-associated endothelin receptor-like receptor

SwissProt ID

O15354 (Human), Q9QY42 (Mouse), Q9QYC6 (Rat)

Gene ID

2861 (GPR37)

Available reactivities

Eq (Equine), Hst (Hamster), Hu (Human), Mky (Monkey), Ms (Mouse), Rb (Rabbit), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of GPR37 / PAEL Receptor antibody

GPR37 is an Orphan-A GPCR with an unknown ligand. GPR37 was recently identified as the PAEL receptor, a Parkin substrate involved in autosomal recessive juvenile Parkinson's (PDJ) disease. The PAEL receptor becomes unfolded, insoluble, and ubiquitinated when overexpressed, leading to unfolded protein-induced cell death. When the PAEL receptor is ubiquitinated by Parkin, it gets degraded, resulting in the suppression of cell death. The insoluble form of the PAEL receptor accumulates in the brains of PDJ patients and may cause selective neuronal death.
GPR37 expression has been reported in brain, liver, and placenta. ESTs have been isolated from brain, embryo, eye, fetal lung/testis/Bcell, gallbladder, heart, liver, liver/spleen, melanocyte/uterus/fetal heart, nerve, placenta, testis, tonsil, and vessel libraries.

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  2. Highly Validated (2)

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GPR37 / PAEL Receptor (N-term, extracell. dom.) antibody

Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Eq, Hst, Hu, Mky, Ms, Rb, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

GPR37 / PAEL Receptor (N-term) antibody

Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky, Rb P
50 µg / €379.00
  OriGene Technologies, Inc.

GPR37 / PAEL Receptor antibody

Western blot analysis of extracts from HuvEc cells, using GPR37 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GPR37 / PAEL Receptor antibody

Western blot analysis of anti-Pael-R (GPR37) Pab (Cat. #TA324840) in mouse brain tissue lysate. Pael-R (GPR37) (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

GPR37 / PAEL Receptor antibody

WB Suggested Anti-GPR37 Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GPR37 / PAEL Receptor antibody

Anti-GPR37 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

GPR37 / PAEL Receptor (N-term extracell. dom.) antibody

Brain, cortex: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Mky, Prim E, P
50 µg / €470.00
  Acris Antibodies GmbH

GPR37 / PAEL Receptor antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GPR37 / PAEL Receptor antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with GPR37 polyclonal antibody ( Cat # PAB4492 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma . Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

GPR37 / PAEL Receptor antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with GPR37 polyclonal antibody ( Cat # PAB4493 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma . Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

GPR37 / PAEL Receptor antibody

Brain, Neurons Rabbit Aff - Purified Hu P
50 µl / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GPR37 / PAEL Receptor

GPR37 / PAEL Receptor Human
10 µg / €540.00
  Abnova Taiwan Corp.

GPR37 / PAEL Receptor

GPR37 / PAEL Receptor Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

13 Item(s)

per page
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