GPR65 / Psychosine receptor antibody

Principal name

GPR65 / Psychosine receptor antibody

Alternative names for GPR65 / Psychosine receptor antibody

G-protein coupled receptor 65, TDAG8, T-cell death-associated protein 8

SwissProt ID

Q61038 (Mouse), Q8IYL9 (Human)

Gene ID

8477 (GPR65)

Available reactivities

Hu (Human), Ms (Mouse), Mky (Monkey), Gorilla, Rt (Rat), Bt (Bat), Can (Canine), Eq (Equine), Por (Porcine), Prim (Primate)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Frozen Sections (C), Western blot / Immunoblot (WB)

Background of GPR65 / Psychosine receptor antibody

GPR65 (TDAG8), a Lysophospholipid/Lysosphingolipid Receptor, is a molecular target for psychosine, a toxic lipid formed by the breakdown of galactosylceramide (cerebroside). A build-up of psychosine, caused by the lack of galactosylceramidase, results in the death of the myelin-synthesizing cells, oligodendrocytes, which is associated with Krabbe disease. Recent evidence suggests that GPR65 is one of the proton-sensing GPCRs coupling to adenylyl cyclase and psychosine and its related lysosphingolipids behave as if they were antagonists against protein-sensing receptors, including TDAG8, GPR4 and OGR1
GPR65 has been reported in human in peripheral blood leukocytes, spleen, lymph node, and thymus. ESTs have been isolated from human B-cell/lung/testis, brain/lung/testis, pancreas/spleen, lung/spleen, leukocyte, embryo, kidney, liver/spleen, thyroid, and vessel libraries.

General readings

Mogi, C., et al. J. Immunol. 182(5):3243-3251 (2009)
Ishii, S., et al. J. Biol. Chem. 280(10):9083-9087 (2005)
Radu, C.G., et al. Proc. Natl. Acad. Sci. U.S.A. 102(5):1632-1637 (2005)

12 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GPR65 / Psychosine receptor (1st cytopl. dom.) antibody

Anti-GPR65 / TDAG8 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Platypus, Por, Prim, Rb, Rt P
50 µg / €345.00
  OriGene Technologies, Inc.

GPR65 / Psychosine receptor (3rd cytopl. dom.) antibody

Anti-GPR65 / TDAG8 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky, Prim, Rb P
50 µg / €345.00
  OriGene Technologies, Inc.

GPR65 / Psychosine receptor antibody

Anti-GPR65 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Hu
50 µg / €345.00
  OriGene Technologies, Inc.

GPR65 / Psychosine receptor antibody

Western Blot: GPR65 Antibody [TA336983] - Analysis of human GPR65 in human kidney lysate in the 1) absence and 2) presence of immunizing peptide using GPR65 antibody at 1 ug/ml. Rabbit Purified Hu, Prim P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GPR65 / Psychosine receptor (C-term) antibody

Western blot analysis of GPR65 (arrow) in Hela cell line lysates (35ug/lane) using GPR65 / Psychosine receptor antibody Cat.-No. AP51930PU-N. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GPR65 / Psychosine receptor antibody

IHC analysis of human tonsil using GPR65 polyclonal antibody ( Cat # PAB0306 ) at 20 µg/ml. Rabbit Gorilla, Hu, Mky C, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

GPR65 / Psychosine receptor antibody

Tonsil, germinal centers and lymphoid follicles Rabbit Aff - Purified Hu P
50 µl / €440.00
  Novus Biologicals Inc.

GPR65 / Psychosine receptor antibody

Lymph node, Hodgkin's Disease Rabbit Aff - Purified Hu P
50 µl / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GPR65 / Psychosine receptor

GPR65 / Psychosine receptor Human
2 µg / €450.00
  Abnova Taiwan Corp.

GPR65 / Psychosine receptor

GPR65 / Psychosine receptor Human
2 µg / €300.00
  Abnova Taiwan Corp.

GPR65 / Psychosine receptor

GPR65 / Psychosine receptor Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

GPR65 / Psychosine receptor

GPR65 / Psychosine receptor Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

12 Item(s)

per page
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