Granzyme K (GZMK) antibody

Principal name

Granzyme K (GZMK) antibody

Alternative names for Granzyme K (GZMK) antibody

Granzyme-3, NK-tryptase-2, Fragmentin-3, TRYP2, NK-Tryp-2

SwissProt ID

O35205 (Mouse), P49863 (Human), P49864 (Rat)

Gene ID

3003 (GZMK), 14945 (Gzmk)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F), ELISA (capture) (E(capture)), ELISA (detection) (E(detection))

Background of Granzyme K (GZMK) antibody

GZMK is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Rucevic M, Fast LD, et al. (2007). Shock. 27(5):488-93.Zhao T, Zhang H, et al. (2007). J Biol Chem. 282(16):12104-11.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Granzyme K (GZMK) antibody

Fig.1: FACS analysis of BOSC23 cells using GM-24C3 DM1209. BOSC23 cells were transiently transfected with anexpression vector encoding either Granzyme K (red curve) oran irrelevant protein (control transfectant: black curve).Binding of GM-24C3 was detected with a PE-conjugatedsecondary antibody. A positive signal was obtained only withGranzyme K transfected cells. Mouse IgG2b GM24C3 Purified Hu E, F
0.1 mg / €330.00
  Acris Antibodies GmbH

Granzyme K (GZMK) antibody

Fig2: BOSC cells were transiently transfected with expression vectors forGranzyme A, B, K, or M. Expression of the constructs was tested with an anti-myc monoclonal antibody (green curves), an irrelevant monoclonal antibodyserved as negative control (black curves). For specificity testing, GM-26E7hybridoma supernatant was tested on all transfectants. A positive signal wasobtained only with Granzyme K transfected cells (red curves). Mouse IgG1 GM26E7 Purified Hu E, E(capture), F
0.1 mg / €330.00
  Acris Antibodies GmbH

Granzyme K (GZMK) antibody

Fig2: BOSC cells were transiently transfected with expression vectors forGranzyme A, B, K, or M. Expression of the constructs was tested with ananti-myc monoclonal antibody (green curves), an irrelevant monoclonalantibody served as negative control (black curves). For specificity testing,GM-6C3 hybridoma supernatant was tested on all transfectants. A positivesignal was obtained only with Granzyme K transfected cells (red curves). Mouse IgG2b GM6C3 Purified Hu E, F
0.1 mg / €330.00
  Acris Antibodies GmbH

Granzyme K (GZMK) antibody

Western blot analysis of extracts from Jurkat cells, using GRAK antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Granzyme K (GZMK) antibody

Immunohistochemistry analysis of Granzyme K (Cat.-No.: AP20485PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Granzyme K (GZMK) antibody

Western Blot analysis of GZMK expression in transfected 293T cell line (H00003003-T02) by GZMK MaxPab polyclonal antibody.

Lane 1: GZMK transfected lysate(29.04 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Granzyme K (GZMK) antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using GRAK Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

Granzyme K (GZMK) antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using GRAK Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

Granzyme K (GZMK) antibody

Human HepG2; WB Suggested Anti-GZMK Antibody Titration: 0.2-1 ug/ml. Positive Control: HepG2 cell lysate; GZMK antibody - N-terminal region (ARP45219_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu, Por WB
50 µg / €350.00
  AVIVA Systems Biology

Granzyme K (GZMK) antibody

Human Spleen; WB Suggested Anti-GZMK Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Spleen; GZMK antibody - middle region (ARP45220_P050) in Human Spleen cells using Western Blot Rabbit Aff - Purified Hu, Por WB
50 µg / €350.00
  AVIVA Systems Biology

Granzyme K (GZMK) antibody

Immunohistochemistry: Granzyme K Antibody [NBP1-19640] -  Granzyme K Antibody [NBP1-19640] - paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Granzyme K (GZMK) antibody

Granzyme K (GZMK) Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Granzyme K (GZMK) antibody

Granzyme K (GZMK) Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

Granzyme K (GZMK) antibody

Western Blot: granzyme K Antibody [NBP1-69353] - This Anti-GZMK antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 0.5ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Granzyme K (GZMK) antibody

Western Blot: granzyme K Antibody [NBP1-69548] - This Anti-GZMK antibody was used in Western Blot of Fetal Spleen   tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Granzyme K (GZMK) (27-264, His-tag)

Granzyme K (GZMK) Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Granzyme K (GZMK) (27-264, His-tag)

Granzyme K (GZMK) Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Granzyme K (GZMK)

Granzyme K (GZMK) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Granzyme K (GZMK)

Granzyme K (GZMK) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Granzyme K (GZMK)

Granzyme K (GZMK) Mouse
0.1 mg / €640.00
  Abnova Taiwan Corp.

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