GRAP2 antibody

Principal name

GRAP2 antibody

Alternative names for GRAP2 antibody

GADS, GRBLG, GRB2L, Grf-40, GRBX, GRID, GRB2-related adapter protein 2, Growth factor receptor-binding protein, GRB-2-like protein, Grf40 adapter protein, Hematopoietic cell-associated adapter protein GrpL, Adapter protein GRID, SH3-SH2-SH3 adapter Mona

SwissProt ID

O75791 (Human), O89100 (Mouse)

Gene ID

9402 (GRAP2), 17444 (Grap2)

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunoprecipitation (IP), Flow Cytometry (F)

Background of GRAP2 antibody

In general, it exists in association with catalytic domains, as in the nonreceptor protein-tyrosine kinases and phospholipase C-γ, within structural proteins, such as spectrin or myosin, and in small adapter proteins, such as Crk and GRB2. SH3 domains are often accompanied by SH2 domains of 100 amino acids that bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins. Deletion or mutation of SH3 domains generally activates the transforming potential of nonreceptor tyrosine kinases, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity. Gads is an adapter proteins that contains both SH2 and SH3 domains. Gads binds to tyrosine-phosphorylated proteins, such as Shc, and functions to couple these proteins to downstream effectors.

General readings

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)
Preisinger, C., et al. Cell. Signal. 22(5):848-856 (2010)
Davila, S., et al. Genes Immun. 11(3):232-238 (2010)
Segat, L., et al. J. Gastroenterol. Hepatol. 24(12):1840-1846 (2009)
Ludwig, L., et al. Cancer Lett. 275(2):194-197 (2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GRAP2 antibody

  GRAP2 mouse monoclonal antibody, clone OTI1G2 (formerly 1G2)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-GRAP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502923) Mouse IgG1 OTI1G2 Purified Hu F, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

GRAP2 (C-term) antibody

  Goat Polyclonal Antibody against GRAP2 / GRID / Grf40  
TA302501 staining (0.5µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Ms, Por WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GRAP2 antibody

  Rabbit polyclonal antibody to GRAP2 (GRB2-related adaptor protein 2)  
Sample (30 ug of whole cell lysate). A: JurKat. 10% SDS PAGE. TA308365 diluted at 1:1000. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GRAP2 antibody

  Rabbit polyclonal anti-GRAP2 antibody  
Western blot analysis of extracts from HuvEc cells, using GRAP2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GRAP2 antibody

  Mouse Monoclonal GRAP2 Antibody  
Western blot detection of GRAP2 in GRAP2 positive cell (CEM,Molt-4,Jurkat) and negative cell (3T3,K562,Hela) lysates using GRAP2 mouse mAb (1:1000 diluted).Predicted band size:38KDa.Observed band size:38KDa. Mouse IgG2b 5C7-F4-E7 Purified WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GRAP2 antibody

GRAP2 Mouse IgG2a UW40 Aff - Purified Hu F, IP, WB
0.1 mg / €260.00
  Acris Antibodies GmbH

GRAP2 antibody

Western blot (WB) analysis of Gads antibody (Cat.-No.: AP21183PU-N) in extracts from HUVEC cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GRAP2 (Center) antibody

Western blot analysis of GRAP2 Antibody (Center) Cat.-No AP51943PU-N in MCF-7 cell line lysates (35ug/lane). This demonstrates the GRAP2 antibody detected the GRAP2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GRAP2 antibody

Western blot analysis of extracts from HuvEc cells, using GRAP2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

GRAP2 antibody

Western blot analysis of extracts from HuvEc cells, using GRAP2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

GRAP2 - human gene knockout kit via CRISPR

GRAP2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GRAP2 - human gene knockout kit via CRISPR

GRAP2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GRAP2 - human gene knockout kit via CRISPR

GRAP2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Grap2 - mouse gene knockout kit via CRISPR

Grap2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Grap2 - mouse gene knockout kit via CRISPR

Grap2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Grap2 - mouse gene knockout kit via CRISPR

Grap2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Grap2 - mouse gene knockout kit via CRISPR

Grap2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GRAP2

  Recombinant protein of human GRB2-related adaptor protein 2 (GRAP2)  
GRAP2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

GRAP2 (1-330, His-tag)

GRAP2 Human Purified > 90 % E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

GRAP2 (1-330, His-tag)

GRAP2 Human Purified > 90 % E. coli
50 µg / €370.00
  Acris Antibodies GmbH

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