GRB14 antibody

Principal name

GRB14 antibody

Alternative names for GRB14 antibody

GRB14 adapter protein, Growth factor receptor-bound protein 14

SwissProt ID

O88900 (Rat), Q14449 (Human), Q5ICW4 (Bovin), Q9JLM9 (Mouse)

Gene ID

2888 (GRB14), 50915 (Grb14), 58844

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of GRB14 antibody

Many growth factors function by binding receptors with intrinsic tyrosine kinase activity. Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and specific phosphotyrosine-containing receptor sequences. GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. An additional member of the GRB7 family, designated GRB14, contains a pleckstrin homology domain in its central region and a carboxy terminal SH2 domain.

General readings

1. Huang O  et al. Grb14 as an independent good prognosis factor for breast cancer patients treated with neoadjuvant chemotherapy. Jpn J Clin Oncol 43:1064-72 (2013).

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GRB14 antibody

  Anti-GRB14 Rabbit Polyclonal Antibody  
Western blot analysis of Human colon cancer tissue using TA322736 (GRB14 Antibody) at dilution 1/200. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GRB14 antibody

  Rabbit Polyclonal Anti-GRB14 Antibody  
Host: Rabbit; Target Name: Grb14; Sample Tissue: Rat Testis lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

GRB14 antibody

Immunohistochemistry (IHC) analyzes of GRB14 antibody (Cat.-No.: AP01405PU-N) in paraffin-embedded human kidney tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GRB14 antibody

Western blot analysis of extracts from HuvEc/COLO/MCF-7 cells, using GRB14 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

GRB14 antibody

Western blot analysis of extracts from HuvEc/COLO/MCF-7 cells, using GRB14 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

GRB14 - human gene knockout kit via CRISPR

GRB14 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GRB14 - human gene knockout kit via CRISPR

GRB14 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GRB14 - human gene knockout kit via CRISPR

GRB14 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GRB14 - human gene knockout kit via CRISPR

GRB14 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Grb14 - mouse gene knockout kit via CRISPR

Grb14 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Grb14 - mouse gene knockout kit via CRISPR

Grb14 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Grb14 - mouse gene knockout kit via CRISPR

Grb14 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GRB14

  Recombinant protein of human growth factor receptor-bound protein 14 (GRB14)  
GRB14 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

GRB14 overexpression lysate

GRB14 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GRB14 (mGFP-tagged) - Human growth factor receptor-bound protein 14 (GRB14), 200 uL, >10^7 TU/mL

Lenti ORF particles, GRB14 (mGFP-tagged) - Human growth factor receptor-bound protein 14 (GRB14), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, GRB14 (Myc-DDK tagged) - Human growth factor receptor-bound protein 14 (GRB14) , 200 uL, >10^7 TU/mL

Lenti ORF particles, GRB14 (Myc-DDK tagged) - Human growth factor receptor-bound protein 14 (GRB14) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Grb14 (GFP-tagged ORF) - Rat growth factor receptor bound protein 14 (Grb14), 200 uL, >10^7 TU/mL

Lenti ORF particles, Grb14 (GFP-tagged ORF) - Rat growth factor receptor bound protein 14 (Grb14), 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Grb14 (Myc-DDK-tagged ORF) - Rat growth factor receptor bound protein 14 (Grb14), 200 uL, >10^7 TU/mL

Lenti ORF particles, Grb14 (Myc-DDK-tagged ORF) - Rat growth factor receptor bound protein 14 (Grb14), 200 uL, >10^7 TU/mL  
200 µl / €1,047.00
  OriGene Technologies, Inc.

18 Item(s)

per page
  • LinkedIn