GRK6 antibody

Principal name

GRK6 antibody

Alternative names for GRK6 antibody

G protein-coupled receptor kinase 6, GPRK6, G protein-coupled receptor kinase GRK6

SwissProt ID

O70293 (Mouse), P43250 (Human), P97711 (Rat)

Gene ID

2870 (GRK6), 26385 (Grk6)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of GRK6 antibody

Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonistmediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first are the second messenger-regulated kinases such as c-AMP dependent protein kinase A and protein kinase C. The second are the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase, GRK 1; two forms of β-adrenergic receptor kinase, GRK 2 (βARK, βARK1) and GRK 3 (βARK2); IT-11 (GRK 4); GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GRK6 antibody

  Rabbit polyclonal anti-GRK6 antibody  
Western blot analysis of extracts from Jurkat cells, COLO205 cells and HUVEC cells, using GRK6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GRK6 antibody

  Rabbit Polyclonal GRK6 Antibody  
Western blot analysis of GRK6 in rat small intestine tissue lysate with GRK6 antibody at 1 ug/ml. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GRK6 antibody

  Rabbit Polyclonal Anti-GRK6 Antibody  
WB Suggested Anti-GRK6 Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Bladder Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GRK6 antibody

Western blot (WB) analysis of GRK 6 antibody (Cat.-No.: AP06692PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GRK6 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

GRK6 antibody

Immunofluorescence analysis of HeLa cells, using GRK6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

GRK6 antibody

Immunofluorescence analysis of HeLa cells, using GRK6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

GRK6A/B antibody

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with untagged GRK5, GRK6 and Kv2.1 plasmids and probed with N142/28 TC supe. Mouse IgG1 N142/28 Supernatant Ms ICC/IF, WB
5 ml / €460.00
  Antibodies Incorporated

NeuroMab

GRK6A/B antibody

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with untagged GRK5, GRK6 and Kv2.1 plasmids and probed with N142/28 TC supe. Mouse IgG1 N142/28 Purified Ms ICC/IF, WB
0.1 ml / €540.00
  Antibodies Incorporated

NeuroMab

CRISPR

Catalog No. Species Donor Vector  

GRK6 - human gene knockout kit via CRISPR

GRK6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GRK6 - human gene knockout kit via CRISPR

GRK6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GRK6 - human gene knockout kit via CRISPR

GRK6 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GRK6 - human gene knockout kit via CRISPR

GRK6 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GRK6 (transcript variant 1)

  Recombinant protein of human G protein-coupled receptor kinase 6 (GRK6), transcript variant 1  
GRK6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

GRK6 overexpression lysate

GRK6 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Lysates (Knockout)

Catalog No.    

GRK6-knockout Cell lysate

GRK6-knockout Cell lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GRK6 (mGFP-tagged) - Human G protein-coupled receptor kinase 6 (GRK6), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, GRK6 (mGFP-tagged) - Human G protein-coupled receptor kinase 6 (GRK6), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, GRK6 (mGFP-tagged) - Human G protein-coupled receptor kinase 6 (GRK6), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, GRK6 (mGFP-tagged) - Human G protein-coupled receptor kinase 6 (GRK6), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, GRK6 (mGFP-tagged)-Human G protein-coupled receptor kinase 6 (GRK6), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, GRK6 (mGFP-tagged)-Human G protein-coupled receptor kinase 6 (GRK6), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,190.00
  OriGene Technologies, Inc.

Lenti ORF particles, GRK6 (Myc-DDK tagged) - Human G protein-coupled receptor kinase 6 (GRK6), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, GRK6 (Myc-DDK tagged) - Human G protein-coupled receptor kinase 6 (GRK6), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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