GSTM1 antibody

Principal name

GSTM1 antibody

Alternative names for GSTM1 antibody

Glutathione S-transferase Mu 1, GST class-mu 1, GSTM1-1, GST1, GSTM1a-1a, GSTM1b-1b, GTH4

SwissProt ID

P04905 (Rat), P09488 (Human), P10649 (Mouse), Q9N0V4 (Bovin)

Gene ID

2944 (GSTM1), 14862 (Gstm1), 24423

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Por (Porcine), Mky (Monkey)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of GSTM1 antibody

Cytosolic and membrane-bound forms of glutathione S-transferase are two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM1 a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual\'s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

General readings

Endo K. et al.: Inhibition of aryl hydrocarbon receptor transactivation and DNA adduct formation by CYP1 isoform-selective metabolic deactivation of benzo[a]pyrene. Toxicol Appl Pharmacol. 2008 Jul 15;230(2):135-43.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GSTM1 antibody

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using GSTM1 mouse mAb with DAB staining. Mouse IgG1 1H4A4 Ascites Hu, Mky E, F, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

GSTM1 antibody

Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using GSTM1 mouse mAb with DAB staining. Mouse IgG1 1H4F2 Ascites Hu, Rt E, F, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

GSTM1 antibody

  Goat Polyclonal Antibody against GSTM1 / GSTM2  
TA302987 (0.3µg/ml) staining of Human Lung lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Mky WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GSTM1 antibody

  Rabbit Polyclonal antibody to GSTM1 (glutathione S-transferase mu 1)  
GSTM1 antibody detects protein by Western blot analysis. A. 50 ug mouse brain lysate/extract. 12 % SDS-PAGE. GSTM1 antibody (TA308892) dilution: 1:1000 Rabbit IgG Aff - Purified Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GSTM1 (C-term) antibody

  Rabbit polyclonal GSTM1 Antibody (C-term)  
Western blot analysis of lysates from Jurkat, U251 cell line and human liver tissue (from left to right), using GSTM1 Antibody (C-term) (Cat. #TA324877). TA324877 was diluted at 1:1000 at each lane. A goat anti-rabbit (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. Rabbit Hu, Ms WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

GSTM1 (1-159) antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt P, WB
50 µl / €470.00
  Acris Antibodies GmbH

GSTM1 antibody

GSTM1 Mouse IgG2a 3B10 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

GSTM1 antibody

GSTM1 Goat Hu, Rt WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

GSTM1 antibody

GSTM1 Rabbit Hu, Rt WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

GSTM1 antibody

Human Jurkat; WB Suggested Anti-GSTM1 Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate; GSTM1 antibody - N-terminal region (ARP41769_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

GSTM1 (C-term) antibody

GSTM1 Rabbit Aff - Purified Hu P, WB
50 µg / €350.00
  AVIVA Systems Biology

GSTM1 antibody

Western blot analysis of GSTM1 expression in HeLa (A); HepG2 (B); rat testis (C) whole cell lysates. Rabbit Aff - Purified Hu, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

GSTM1 antibody

Western blot analysis of GSTM1 expression in HeLa (A); HepG2 (B); rat testis (C) whole cell lysates. Rabbit Aff - Purified Hu, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

GSTM1 antibody

Western blot analysis of GSTM1 expression in HeLa (A); HepG2 (B); rat testis (C) whole cell lysates. Rabbit Aff - Purified Hu, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CRISPR

Catalog No. Species Donor Vector  

GSTM1 - human gene knockout kit via CRISPR

GSTM1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GSTM1 - human gene knockout kit via CRISPR

GSTM1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GSTM1 - human gene knockout kit via CRISPR

GSTM1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GSTM1 - human gene knockout kit via CRISPR

GSTM1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gstm1 - mouse gene knockout kit via CRISPR

Gstm1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gstm1 - mouse gene knockout kit via CRISPR

Gstm1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

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