GSTM5 antibody

Principal name

GSTM5 antibody

Alternative names for GSTM5 antibody

Glutathione S-transferase Mu 5, GSTM5-5, GST class-mu 5

SwissProt ID

P46439 (Human), P48774 (Mouse), Q9Z1B2 (Rat)

Gene ID

2949 (GSTM5), 14866 (Gstm5), 64352

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of GSTM5 antibody

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual\'s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual\'s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.

General readings

Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)
Yu, K.D., et al. Breast Cancer Res. Treat. 121(2):485-496(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Moyer, A.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(3):811-821(2010)
Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GSTM5 (N-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with  GSTM5 Antibody (N-term) Cat.-No AP51967PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

GSTM5 - human gene knockout kit via CRISPR

GSTM5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GSTM5 - human gene knockout kit via CRISPR

GSTM5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GSTM5 - human gene knockout kit via CRISPR

GSTM5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GSTM5 - human gene knockout kit via CRISPR

GSTM5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gstm5 - mouse gene knockout kit via CRISPR

Gstm5 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gstm5 - mouse gene knockout kit via CRISPR

Gstm5 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gstm5 - mouse gene knockout kit via CRISPR

Gstm5 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gstm5 - mouse gene knockout kit via CRISPR

Gstm5 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GSTM5

  Recombinant protein of human glutathione S-transferase mu 5 (GSTM5)  
GSTM5 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

GSTM5 (1-218, His-tag)

GSTM5 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

GSTM5 (1-218, His-tag)

GSTM5 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GSTM5 (mGFP-tagged) - Human glutathione S-transferase mu 5 (GSTM5), 200 uL, >10^7 TU/mL

Lenti ORF particles, GSTM5 (mGFP-tagged) - Human glutathione S-transferase mu 5 (GSTM5), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, GSTM5 (Myc-DDK tagged) - Human glutathione S-transferase mu 5 (GSTM5) , 200 uL, >10^7 TU/mL

Lenti ORF particles, GSTM5 (Myc-DDK tagged) - Human glutathione S-transferase mu 5 (GSTM5) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gstm5 (GFP-tagged) - Mouse glutathione S-transferase, mu 5 (Gstm5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gstm5 (GFP-tagged) - Mouse glutathione S-transferase, mu 5 (Gstm5), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gstm5 (Myc-DDK-tagged) - Mouse glutathione S-transferase, mu 5 (Gstm5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gstm5 (Myc-DDK-tagged) - Mouse glutathione S-transferase, mu 5 (Gstm5), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gstm5 (GFP-tagged ORF) - Rat glutathione S-transferase, mu 5 (Gstm5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gstm5 (GFP-tagged ORF) - Rat glutathione S-transferase, mu 5 (Gstm5), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gstm5 (Myc-DDK-tagged ORF) - Rat glutathione S-transferase, mu 5 (Gstm5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gstm5 (Myc-DDK-tagged ORF) - Rat glutathione S-transferase, mu 5 (Gstm5), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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