GTF3C3 antibody

Principal name

GTF3C3 antibody

Alternative names for GTF3C3 antibody

Transcription factor IIIC subunit gamma, TFIIIC 102 kDa subunit, TFIIIC102, TFIIIC gamma, General transcription factor 3C polypeptide 3

SwissProt ID

Q9Y5Q9 (Human)

Gene ID

9330 (GTF3C3)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat), Bov (Bovine), Eq (Equine), Por (Porcine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair), Paraffin Sections (P)

Background of GTF3C3 antibody

RNA polymerase (pol) III synthesizes tRNA, 5s rRNA, 7SL RNA and U6 snRNA and is overexpressed in many transformed cell lines and tumors in vivo, since cells must duplicate its protein components before division. Therefore, in order to maintain rapid growth, cells must produce a high level of Pol III transcribed RNA, which requires the presence of the TFIIIB and TFIIIC2 transcription factor complexes. The TFIIIC2 complex is composed of five subunits, TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, that are overexpressed in adenovirus transformed cells as well as in malignant cells in vivo, such as ovarian carcinomas. TFIIIC2 recruits RNA pol III and TFIIIB to promoter elements and may be a key component in the deregulation of malignant cells. The TFIIIB complex includes the TATA-binding protein (TBP), TFIIB-related factor 1 (BRF1) and TFIIIB, the expression of which are also upregulated in transformed cells. In many carcinomas, the tumor suppressors retinoblastoma (RB) and p53 are inactivated, which affects their ability to bind and inactivate the function of TFIIIB.

General readings

Zhan,Y., et al., (2002) Cell Death Differ. 9 (4), 439-447

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GTF3C3 antibody

Western blot analysis of extracts from 293 cells, using TF3C3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

GTF3C3 antibody

WB Suggested Anti-GTF3C3 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysateGTF3C3 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

GTF3C3 antibody

WB Suggested Anti-GTF3C3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 721_B cell lysate. GTF3C3 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

GTF3C3 antibody

Immunohistochemistry  (IHC) analyzes of TFIIIC102 antibody (Cat.-No.: AP20464PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

GTF3C3 antibody

GTF3C3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

GTF3C3 antibody

Immunofluorescence of purified MaxPab antibody to GTF3C3 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

GTF3C3 antibody

GTF3C3 MaxPab rabbit polyclonal antibody. Western Blot analysis of GTF3C3 expression in human kidney. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

GTF3C3 antibody

GTF3C3 monoclonal antibody (M01), clone 2D8. Western Blot analysis of GTF3C3 expression in NIH/3T3 ( Cat # L018V1 ). Mouse IgG2b 2D8 Purified Hu, Ms E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GTF3C3 antibody

Western blot analysis of GTF3C3 over-expressed 293 cell line, cotransfected with GTF3C3 Validated Chimera RNAi ( Cat # H00009330-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with GTF3C3 monoclonal antibody (M02), clone 3D9 (Cat # H00009330-M02 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. Mouse IgG2b 3D9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GTF3C3 antibody

Western blot analysis of extracts from 293 cells, using TF3C3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

GTF3C3 antibody

Western blot analysis of extracts from 293 cells, using TF3C3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

GTF3C3 antibody

Human HepG2; WB Suggested Anti-GTF3C3 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate. GTF3C3 is supported by BioGPS gene expression data to be expressed in HepG2.; GTF3C3 antibody - N-terminal region (ARP35841_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

GTF3C3 antibody

Human 721_B; WB Suggested Anti-GTF3C3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: 721_B cell lysate. GTF3C3 is supported by BioGPS gene expression data to be expressed in 721_B.; GTF3C3 antibody - N-terminal region (ARP38949_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Can, Hu WB
50 µg / €350.00
  AVIVA Systems Biology

GTF3C3 antibody

Immunohistochemical analysis of GTF3C3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

GTF3C3 antibody

Immunohistochemical analysis of GTF3C3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

GTF3C3 antibody

Immunohistochemical analysis of GTF3C3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

GTF3C3 antibody

Western Blot and IP: GTF3C3 Antibody [NB100-60430] - Detection of Human GTF3C3/TFIIIC102 on HeLa whole cell lysate using NB100-60430. GTF3C3/TFIIIC102 was also immunoprecipitated by rabbit anti-GTF3C3/TFIIIC102 antibody NB100-60431. Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

GTF3C3 antibody

GTF3C3 Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

GTF3C3 antibody

GTF3C3 Rabbit IgG Aff - Purified Hu, Ms E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GTF3C3

GTF3C3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

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