Guanylate cyclase soluble GUCY1B3 antibody

Principal name

Guanylate cyclase soluble GUCY1B3 antibody

Alternative names for Guanylate cyclase soluble GUCY1B3 antibody

GCS-beta-1, GCS-beta-3, GUC1B3, GUCSB3, GUCY1B1, sGC beta, Guanylate cyclase soluble subunit beta-1, Guanylate cyclase soluble subunit beta-3, Soluble guanylate cyclase small subunit

SwissProt ID

O54865 (Mouse), P16068 (Bovin), P20595 (Rat), Q02153 (Human), Q4ZHR9 (Canfa)

Gene ID

2983 (GUCY1B3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), African clawed frog, Xen (Xenopus), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Guanylate cyclase soluble GUCY1B3 antibody

The cellular levels of Cyclic GMP (cGMP), a key messenger in several signal transduction pathways, are maintained by the orchestrated activities of two opposing enzymes: synthesizing gualylyl cyclases (GC) and hydrolyzing phosphodiesterases (PDEs). The synthesizing enzymes (GCs) are found in two forms: cytosolic (soluble) and membrane-bound (particulate). In last several years new members of particulate guanylate cyclase family have been identified and significant progress is made in understanding the molecular mechanisms that underlie the regulation of these family of enzymes. In response to G-protein couples receptor stimulation, the cGMP can be produced from GTP by either cytoplasmic, soluble guanylate cyclase (sGC) are heterodimers (a and b polypeptide chains), that are stimulated by nitric oxide and carbon monoxide or by particulate membrane-bound guanylyl cyclases which are activated by a complex mechanism by natriuretic peptides. Particulate GC (PGCs) have 7 different isoforms, PGC-A through PGC-G and are expressed in most tissues in isoform specific manner (See Table 1). There is significant structural homology among various PGCs, there is a large N-terminal extracellular domain (ECD), a single TMD and a large intracellular domain with protein kinase activity (KLD), a C-terminal catalytic domain (CD) and in between is a dimmerization domain (DD). It has been shown that a significant number hippocampal astrocytes (67%) contained both soluble and particulate guanylate cyclases in the same cell (2).

General readings

Slavov,D., (2006) Int. J. Impot. Res. 18 (5), 432-437

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Guanylate cyclase soluble GUCY1B3 (189-207) antibody

Human cerebellum stained with Anti-GC beta, Cat# AP15591PU Rabbit Purified Hu, Ms, Rt P
0.5 ml / €360.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 (189-207) antibody

Human cerebellum stained with Anti-GC beta, Cat# AP15591PU Rabbit Purified Hu, Ms, Rt P
1 ml / €520.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 (189-207) antibody

Human cerebellum stained with Anti-GC beta, Cat# AP15591PU Rabbit Purified Hu, Ms, Rt P
0.1 ml / €190.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 antibody

Western blot analysis of extracts from HuvEc cells, using Guanylate Cyclase ß antibody (#TA313988).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Guanylate cyclase soluble GUCY1B3 antibody

WB Suggested Anti-GUCY1B3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: 293T cell lysate.GUCY1B3 is supported by BioGPS gene expression data to be expressed in HEK293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Guanylate cyclase soluble GUCY1B3 antibody

Guanylate cyclase soluble GUCY1B3 Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Guanylate cyclase soluble GUCY1B3 antibody

Immunohistochemistry analysis of Guanylate cyclase soluble GUCY1B3 (Antibody Cat.-No AP06153PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 control peptide

Guanylate cyclase soluble GUCY1B3
0.1 mg / €250.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 (189-207) antibody

Western Blot of Soluble Guanylyl Cyclase Beta antibody (Cat#AP10315PU-N) Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 (C-term) antibody

Western blot analysis of anti-GUCY1B3 Pab in Y79 cell line lysate. GUCY1B3(arrow) was detected using the purified Pab Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 (189-207) antibody

Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with GUCY1B3 antibody AP22710PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Hu, Ms, Rt P
0.25 ml / €470.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 antibody

Guanylate cyclase soluble GUCY1B3 Mouse IgG2a GC25 Hu E, WB
0.2 mg / €560.00
  Abnova Taiwan Corp.

Guanylate cyclase soluble GUCY1B3 antibody

Guanylate cyclase soluble GUCY1B3 Mouse IgG2a GC30 Hu E, WB
0.2 mg / €560.00
  Abnova Taiwan Corp.

Guanylate cyclase soluble GUCY1B3 antibody

Western blot analysis of GUCY1B3 polyclonal antibody ( Cat # PAB4059 ) in Y-79 cell lysate. GUCY1B3 ( arrow ) was detected using the purified polyclonal antibody. Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Guanylate cyclase soluble GUCY1B3 antibody

Immunohistochemical staining of GUCY1B2 on formalin fixed, paraffin embedded human cerebellum with GUCY1B3 polyclonal antibody. Rabbit Hu P
0.1 ml / €390.00
  Abnova Taiwan Corp.

Guanylate cyclase soluble GUCY1B3 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Guanylate Cyclase beta Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

Guanylate cyclase soluble GUCY1B3 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Guanylate Cyclase beta Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

Guanylate cyclase soluble GUCY1B3 antibody

Human 293T; WB Suggested Anti-GUCY1B3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: 293T cell lysate. GUCY1B3 is supported by BioGPS gene expression data to be expressed in HEK293T.; GUCY1B3 antibody - N-terminal region (ARP46012_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Guanylate cyclase soluble GUCY1B3 antibody

Immunohistochemical analysis of GUCY1B3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Guanylate cyclase soluble GUCY1B3 antibody

Immunohistochemical analysis of GUCY1B3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

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