Guanylate cyclase soluble GUCY1B3 antibody

Principal name

Guanylate cyclase soluble GUCY1B3 antibody

Alternative names for Guanylate cyclase soluble GUCY1B3 antibody

GCS-beta-1, GCS-beta-3, GUC1B3, GUCSB3, GUCY1B1, sGC beta, Guanylate cyclase soluble subunit beta-1, Guanylate cyclase soluble subunit beta-3, Soluble guanylate cyclase small subunit

SwissProt ID

O54865 (Mouse), P16068 (Bovin), P20595 (Rat), Q02153 (Human), Q4ZHR9 (Canfa)

Gene ID

2983 (GUCY1B3), 54195 (Gucy1b3), 25202

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Guanylate cyclase soluble GUCY1B3 antibody

The cellular levels of Cyclic GMP (cGMP), a key messenger in several signal transduction pathways, are maintained by the orchestrated activities of two opposing enzymes: synthesizing gualylyl cyclases (GC) and hydrolyzing phosphodiesterases (PDEs). The synthesizing enzymes (GCs) are found in two forms: cytosolic (soluble) and membrane-bound (particulate). In last several years new members of particulate guanylate cyclase family have been identified and significant progress is made in understanding the molecular mechanisms that underlie the regulation of these family of enzymes. In response to G-protein couples receptor stimulation, the cGMP can be produced from GTP by either cytoplasmic, soluble guanylate cyclase (sGC) are heterodimers (a and b polypeptide chains), that are stimulated by nitric oxide and carbon monoxide or by particulate membrane-bound guanylyl cyclases which are activated by a complex mechanism by natriuretic peptides. Particulate GC (PGCs) have 7 different isoforms, PGC-A through PGC-G and are expressed in most tissues in isoform specific manner (See Table 1). There is significant structural homology among various PGCs, there is a large N-terminal extracellular domain (ECD), a single TMD and a large intracellular domain with protein kinase activity (KLD), a C-terminal catalytic domain (CD) and in between is a dimmerization domain (DD). It has been shown that a significant number hippocampal astrocytes (67%) contained both soluble and particulate guanylate cyclases in the same cell (2).

General readings

Slavov,D., (2006) Int. J. Impot. Res. 18 (5), 432-437

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Guanylate cyclase soluble GUCY1B3 antibody

  Rabbit polyclonal Guanylate Cyclase beta antibody  
Western blot analysis of extracts from HuvEc cells, using Guanylate Cyclase ß antibody (#TA313988).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Guanylate cyclase soluble GUCY1B3 antibody

  Rabbit Polyclonal Anti-GUCY1B3 Antibody  
WB Suggested Anti-GUCY1B3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: 293T cell lysate.GUCY1B3 is supported by BioGPS gene expression data to be expressed in HEK293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Guanylate cyclase soluble GUCY1B3 antibody

  Rabbit Polyclonal Anti-GCYB1 Antibody  
Guanylate cyclase soluble GUCY1B3 Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Guanylate cyclase soluble GUCY1B3 antibody

  Rabbit Polyclonal anti-Guanylyl Cyclase beta Antibody  
Human Brain stained with anti-Guanylyl Cyclase beta antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Guanylate cyclase soluble GUCY1B3 antibody

Immunohistochemistry analysis of Guanylate cyclase soluble GUCY1B3 (Antibody Cat.-No AP06153PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 control peptide

Guanylate cyclase soluble GUCY1B3
0.1 mg / €250.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 (189-207) antibody

Western Blot of Soluble Guanylyl Cyclase Beta antibody (Cat#AP10315PU-N) Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 (C-term) antibody

Western blot analysis of anti-GUCY1B3 Pab in Y79 cell line lysate. GUCY1B3(arrow) was detected using the purified Pab Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 (189-207) antibody

Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with GUCY1B3 antibody AP22710PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Hu, Ms, Rt P
0.25 ml / €470.00
  Acris Antibodies GmbH

Guanylate cyclase soluble GUCY1B3 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Guanylate Cyclase beta Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

Guanylate cyclase soluble GUCY1B3 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Guanylate Cyclase beta Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

Guanylate cyclase soluble GUCY1B3 (beta subunit) antibody

Guanylate cyclase soluble GUCY1B3 Mouse IgG2a GC25 Purified Hu E, WB
1 mg / €530.00
  HyTest Ltd.

CRISPR

Catalog No. Species Donor Vector  

GUCY1B3 - human gene knockout kit via CRISPR

GUCY1B3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GUCY1B3 - human gene knockout kit via CRISPR

GUCY1B3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GUCY1B3 - human gene knockout kit via CRISPR

GUCY1B3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GUCY1B3 - human gene knockout kit via CRISPR

GUCY1B3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Guanylate cyclase soluble GUCY1B3

  Recombinant protein of human guanylate cyclase 1, soluble, beta 3 (GUCY1B3)  
Guanylate cyclase soluble GUCY1B3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, GUCY1B3 (mGFP-tagged) - Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3), 200 uL, >10^7 TU/mL

Lenti ORF particles, GUCY1B3 (mGFP-tagged) - Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, GUCY1B3 (Myc-DDK tagged) - Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3) , 200 uL, >10^7 TU/mL

Lenti ORF particles, GUCY1B3 (Myc-DDK tagged) - Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gucy1b3 (GFP-tagged) - Mouse guanylate cyclase 1, soluble, beta 3 (Gucy1b3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Gucy1b3 (GFP-tagged) - Mouse guanylate cyclase 1, soluble, beta 3 (Gucy1b3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,280.00
  OriGene Technologies, Inc.

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