GUCY2C / STA receptor antibody

Principal name

GUCY2C / STA receptor antibody

Alternative names for GUCY2C / STA receptor antibody

Heat-stable enterotoxin receptor, hSTAR, GUC2C, STAR, Guanylyl cyclase C, Intestinal guanylate cyclase, GC-C

SwissProt ID

P23897 (Rat), P25092 (Human), P55204 (Pig), P70106 (Cavpo), Q3UWA6 (Mouse)

Gene ID

2984 (GUCY2C)

Available reactivities

Hu (Human), Bov (Bovine), Mky (Monkey)

Available hosts

Mouse, Rabbit, Chicken

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of GUCY2C / STA receptor antibody

Guanylate Cyclase is an heterodimer of an alpha and a beta chain. Its enzymatic activity transforms GTP to GMP releasing a diphosphate. It binds 1 or 2 hemes per heterodimer. It is activated by nitric oxide in the presence of magnesium or manganese ions. There are two types of guanylate cyclase: soluble form and membrane-associated receptor form.

General readings

1. Debruyne,P.R., Witek,M., Gong,L., Birbe,R., Chervoneva,I., Jin,T., Domon-Cell,C., Palazzo,J.P., Freund,J.N., Li,P., Pitari,G.M.,, et al.
Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells
2. Mann,E.A., Steinbrecher,K.A., Stroup,C., Witte,D.P., Cohen,M.B. and Giannella,R.A.
Lack of guanylyl cyclase C, the receptor for Escherichia coli heat-stable enterotoxin, results in reduced polyp formation and increased apoptosis in the multiple intestinal neoplasia (Min) mouse model
3. Ghanekar,Y., Chandrashaker,A., Tatu,U. and Visweswariah,S.S., et al.
Glycosylation of the receptor guanylate cyclase C: role in ligand binding and catalytic activity
4. Tien,Y.W., Lee,P.H., Hu,R.H., Hsu,S.M. and Chang,K.J., et al.
The role of gelatinase in hepatic metastasis of colorectal cancer
5. Singh,R., et al.
Interaction of guanylyl cyclase C with SH3 domain of Src tyrosine kinase. Yet another mechanism for desensitization
6. , de Sauvage F.J., Camerato T.R., Goeddel D.V.
Primary structure and functional expression of the human receptor for Escherichia coli heat-stable enterotoxin.
7. , Singh S., Singh G., Heim J.M., Gerzer R.
Isolation and expression of a guanylate cyclase-coupled heat stable enterotoxin receptor cDNA from a human colonic cell line.
8. , Mann E.A., Jump M.L., Giannella R.A.
Cell line-specific transcriptional activation of the promoter of the human guanylyl cyclase C/heat-stable enterotoxin receptor gene.
9. , Mann E.A., Cohen M.B., Giannella R.A.
Comparison of receptors for Escherichia coli heat-stable enterotoxin: novel receptor present in IEC-6 cells.
10. , Scott R.O., Thelin W.R., Milgram S.L.
A novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptor.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GUCY2C / STA receptor (248-262) antibody

GUCY2C / STA receptor Rabbit Serum Hu WB
0.1 ml / €440.00
  Acris Antibodies GmbH

GUCY2C / STA receptor (248-262) antibody

GUCY2C / STA receptor Rabbit Serum Hu WB
20 µl / €160.00
  Acris Antibodies GmbH

GUCY2C / STA receptor antibody

GUCY2C / STA receptor Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

Detection limit for recombinant GST tagged GUCY2C is approximately 0.3ng/ml as a capture antibody. Mouse IgG2b 2F3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C monoclonal antibody (M02), clone 1B11 Western Blot analysis of GUCY2C expression in 293 ( Cat # L026V1 ). Mouse IgG2b 1B11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C / STA receptor Mouse IgG2a 3D5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C monoclonal antibody (M04), clone 2H8 Western Blot analysis of GUCY2C expression in U-2 OS ( Cat # L022V1 ). Mouse IgG2b 2H8 Purified Hu E, WB
50 µg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C monoclonal antibody (M04), clone 2H8 Western Blot analysis of GUCY2C expression in U-2 OS ( Cat # L022V1 ). Mouse IgG2b 2H8 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C monoclonal antibody (M05), clone 1E1 Western Blot analysis of GUCY2C expression in COLO 320 HSR ( Cat # L020V1 ). Mouse IgG2b 1E1 Purified Hu E, WB
50 µg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C monoclonal antibody (M05), clone 1E1 Western Blot analysis of GUCY2C expression in COLO 320 HSR ( Cat # L020V1 ). Mouse IgG2b 1E1 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C / STA receptor Mouse IgG2b 3C2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C / STA receptor Mouse IgG2b 3H6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

Detection limit for recombinant GST tagged GUCY2C is approximately 0.3ng/ml as a capture antibody. Mouse IgG2b 3D2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C monoclonal antibody (M09), clone 2G7 Western Blot analysis of GUCY2C expression in U-2 OS ( Cat # L022V1 ). Mouse IgG2b 2G7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C / STA receptor Mouse IgG2b 1D11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

Detection limit for recombinant GST tagged GUCY2C is approximately 10ng/ml as a capture antibody. Mouse IgG2b 1G5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C / STA receptor Mouse IgG2b 3H1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

GUCY2C / STA receptor Mouse IgG2b 3H3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

GUCY2C / STA receptor antibody

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-GUCY2C ) Chicken Aff - Purified Bov, Hu, Mky WB
50 µg / €510.00
  Novus Biologicals Inc.

GUCY2C / STA receptor antibody

Immunohistochemistry-Paraffin: GUCY2C Antibody [NBP1-81788] Immunohistochemical staining of human lateral ventricle shows strong cytoplasmic positivity in neuronal cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

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