HAP1 antibody

Principal name

HAP1 antibody

Alternative names for HAP1 antibody

Huntingtin-associated protein 1, HAP-1, HAP2, HLP1, Neuroan 1

SwissProt ID

O35668 (Mouse), P54256 (Rat), P54257 (Human)

Gene ID

9001 (HAP1), 29430 (Hap1), 15114

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunoprecipitation (IP), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of HAP1 antibody

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. It is a progressive disorder that generally begins in middle age with abnormalities of movement, cognition, personality and mood.
Huntingtin-associated protein-1 is highly expressed in brain and shown to mediate the neuropathology of HD. The human protein interacts with huntingtin, with two cytoskeletal proteins (Dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Two transcripts encoding different isoforms have been identified but one is a nonsense-mediated decay (NMD) candidate.

General readings

Takeshita Y, Fujinaga R, Zhao C, Yanai A, Shinoda K.
Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis.
Hum Mol Genet. 2006 Aug 1;15(15):2298-312. Epub 2006 Jun 16.
PMID: 16782802

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HAP1 (C-term) antibody

AP23773PU-N HAP-1 antibody staining of Mouse Brain lysate at 0.1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Ms, Rt E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

HAP1 antibody

TA303170 (0.1µg/ml) staining of Human Brain (Hippocampus) lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HAP1 antibody

Western blot analysis of HAP1 in mouse brain tissue lysate with HAP1 antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HAP1 antibody

Western Blot: HAP1 Antibody - Western blot analysis of HAP1 using Lane 1: mouse brain lysate and Lane 2: human brain lysate. Mouse IgG1 1B6 Purified Hu, Ms, Rt C, IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HAP1 antibody

Brain, cortex: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

HAP1 (639-653) antibody

Figure 1. AP07921PU-N HAP1 antibody staining of Formalin-Fixed Paraffin-Embedded Human Adrenal tissue. Rabbit Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

HAP1 Control Peptide

HAP1
50 µg / €160.00
  Acris Antibodies GmbH

HAP1 antibody

HAP1 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HAP1 antibody

Western Blot analysis of HAP1 expression in transfected 293T cell line (H00009001-T01) by HAP1 MaxPab polyclonal antibody.

Lane 1: HAP1 transfected lysate(73.81 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

HAP1 antibody

Western blot analysis of Hap1 in mouse brain lysate using Hap1 monoclonal antibody, clone 1B6 ( Cat # MAB2312 ). Mouse IgG1 1B6 Hu, Ms, Rt C, IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

HAP1 antibody

IHC on rat DRG ( free floating cryo section ) using rabbit Hap1 polyclonal antibody ( Cat # PAB0702 ) at a dilution of 1 : 1000. Rabbit Rt C
0.1 ml / €390.00
  Abnova Taiwan Corp.

HAP1 antibody

HAP1 polyclonal antibody ( Cat # PAB7160 ) ( 0.1 µg/ml ) staining of human brain ( hippocampus ) lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

HAP1 antibody

HAP1 Goat Ms, Rt E
0.1 mg / €400.00
  Abnova Taiwan Corp.

HAP1 antibody

Immunohistochemistry of HAP1 in human brain tissue with HAP1 polyclonal antibody ( Cat # PAB12994 ) at 2.5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

HAP1 antibody

Western Blot: HAP1 Antibody [NB100-55413] - NB100-55413 (0.1ug/ml) staining of Human Brain (Hippocampus) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

HAP1 antibody

HAP1 Mouse IgG1 1B6 Biotin Hu, Ms, Rt C, IP, P, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

HAP1 antibody

HAP1 Mouse IgG1 1B6 DyLight488 Hu, Ms, Rt C, IP, P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

HAP1 antibody

HAP1 Mouse IgG1 1B6 HRP Hu, Ms, Rt C, IP, P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

HAP1 antibody

HAP1 Mouse IgG1 1B6 Purified Hu, Ms, Rt C, IP, P, WB
25 µl / €200.00
  Novus Biologicals Inc.

HAP1 antibody

Immunohistochemistry-Paraffin: HAP1 Antibody [NBP1-76793] - Human brain tissue with HAP1 antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

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