Haptoglobin antibody

Principal name

Haptoglobin antibody

SwissProt ID

P00738 (Human), P06866 (Rat), P19006 (Canfa), P19007 (Rabit), Q2TBU0 (Bovin), Q61646 (Mouse), Q8SPS7 (Pig)

Gene ID

3240 (HP), 280692, 397061, 15439 (Hp), 24464, 100008816

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Bov (Bovine)

Available hosts

Rabbit, Sheep, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Frozen Sections (C), Immunodiffusion (ID), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Radioimmunoassay (R), Immunoprecipitation (IP), Flow Cytometry (F), Luminex (LMNX)

Background of Haptoglobin antibody

Haptoglobin (HP), is a protein that in humans is encoded by the HP gene. Haptoglobin, a plasma glycoprotein that binds free hemoglobin, has a tetrameric structure of 2 alpha and 2 beta polypeptides that are covalently associated by disulfide bonds. Haptoglobin is homologous to serine proteases of the chymotrypsinogen family. In the chimpanzee, there are 3 genes in the haptoglobin family (haptoglobin, HP; haptoglobin-related, HPR; and haptoglobin-primate, HPP), whereas only 2 genes exist in humans (HP and HPR). There are similarities between the primary structures of the alpha chain and of light chains of gamma globulins. The alpha haptoglobin locus is on the long arm of chromosome 16, where its exact cytogenetic location is 16q22.2. A major function of haptoglobin is to bind hemoglobin (Hb) to form a stable Hp-Hb complex and thereby prevent Hb-induced oxidative tissue damage. Haptoglobin is an unusual secretory protein in that it is proteolytically processed in the endoplasmic reticulum and not in the Golgi. The human haptoglobin HP*2 allele contains a 1.7-kb intragenic duplication that arose after a unique nonhomologous recombination between the prototype HP*1 alleles.

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Savy, M., et al. PLoS ONE 5 (6), E11075 (2010)
Kasvosve, I., et al. Adv Clin Chem 50, 23-46 (2010)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Haptoglobin antibody

Immunohistochemical staining of paraffin-embedded lung tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG1 UMAB10 Purified Hu WB
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

Haptoglobin antibody

Immunohistochemical staining of paraffin-embedded lung tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG1 UMAB10 Purified Hu WB
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

Haptoglobin antibody

Anti-HP mouse monoclonal antibody (TA501699) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HP(RC223612). Mouse IgG2a OTI4H5 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Haptoglobin antibody

HP ELISA with 4C2 Capture (TA600401) and 2B8 Detection (TA700399) Antibodies. Substrate used: Recombinant Human HP (TP323612) Mouse IgG1 OTI2B8 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

Haptoglobin (Center) antibody

Confocal immunofluorescent analysis of Haptoglobin Antibody (Center) Cat.-No AP52089PU-N with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). Rabbit Ig Aff - Purified Hu F, ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Haptoglobin antibody

Haptoglobin antibody detects Haptoglobin protein by Western blot analysis. A. 30 ug HeLa whole cell lysate/extract. B. 30 ug HepG2 whole cell lysate/extract. C. 30 ug A375 whole cell lysate/extract. 10% SDS-PAGE. Haptoglobin antibody (TA308899) dilution: Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Haptoglobin antibody

Immunohistochemical analysis of paraffin-embedded Normal gastric, using Haptoglobin(TA308900) antibody at 1:100 dilution. Rabbit IgG Aff - Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Haptoglobin antibody

Haptoglobin Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Haptoglobin antibody

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (HP Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Haptoglobin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HP (RC223612, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HP. Mouse IgG2a OTI1F9 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Haptoglobin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HP (RC223612, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HP. Mouse IgG1 OTI2B11 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Haptoglobin antibody

Anti-HP mouse monoclonal antibody (TA501697) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HP(RC223612). Mouse IgG2b OTI2B8 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Haptoglobin antibody

Anti-HP mouse monoclonal antibody (TA501698) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HP(RC223612). Mouse IgG1 OTI6H2 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Haptoglobin antibody

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-HP monoclonal antibody. Mouse IgG1 OTI1B1 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Haptoglobin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HP (RC223612, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HP. Mouse IgG1 OTI2B9 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Haptoglobin antibody

Anti-HP mouse monoclonal antibody (TA501813) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HP(RC223612). Mouse IgG2b OTI4C2 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Haptoglobin antibody

ELISA: Haptoglobin Antibody - Affinity Purified Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

Haptoglobin antibody

HP ELISA with 1F9 Capture (TA600399) and 2B8 Detection (TA700399) Antibodies. Substrate used: Recombinant Human HP (TP323612) Mouse IgG1 OTI1F9 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

Haptoglobin antibody

HP Luminex ELISA with 2B8 Capture (TA600400) and 1F9 Detection (TA700400) Antibodies. Substrate used: Recombinant Human HP (TP323612) Mouse IgG1 OTI2B8 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

Haptoglobin antibody

HP ELISA with 4C2 Capture (TA600401) and 2B8 Detection (TA700399) Antibodies. Substrate used: Recombinant Human HP (TP323612) Mouse IgG1 OTI4C2 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

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