Harakiri / HRK antibody

Principal name

Harakiri / HRK antibody

Alternative names for Harakiri / HRK antibody

Neuronal death protein DP5, BID3, Activator of apoptosis harakiri, BH3-interacting domain-containing protein 3

SwissProt ID

O00198 (Human), P62816 (Mouse), P62817 (Rat)

Gene ID

8739 (HRK)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Flow Cytometry (F), Immunoprecipitation (IP)

Background of Harakiri / HRK antibody

Apoptosis or programmed cell death is a physiological cellular process characterized by cell shrinkage, membrane blebbing, DNA fragmentation, and release of Cytochrome C from the mitochondria. It is utilized by the organism to get rid of unwanted cells, which is critical for normal development and homeostasis of an organism. Disregulation of normal apoptosis process have been implicated in a variety of diseases, including cancer, autoimmune diseases, viral infections, etc. Programmed cell death occurs through complex cascades of cell signaling in which Bcl-2 family members, among others, play an important role.The Bcl-2 family of proteins regulate apoptosis as well as execute death signals at the mitochondrion. Members of this family include both pro- and anti-apoptotic proteins that hare homology sequences called Bcl-2 Homology domains (BH1-4) which mediate dimmer formation. The BH3 proteins, such as BID, NOXA, PUMA, BIK, BIM and BAD are all pro-apoptotic and share sequence homology within the amphipathic alpha-helical BH3 region, which is required for their apoptotic function. They may trigger release of death-inducing molecules such as Cytochrome C, Smac, and endonuclease G. Anti-apoptotic family members, including Bcl-2 and Bcl-XL, play inhibitory roles. Bcl-2 family proteins may form homodimers or heterodimers between pro- and anti-apoptotic members, the ratios of which determine the cell fate.

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Harakiri / HRK antibody

Western blot analysis of Hrk in mouse pancreas tissue lysate with Hrk antibody at (A) 2.5 and (B) 5 µg/ml. Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Harakiri / HRK antibody

Hrk-BH3 (Cat. #TA324509) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Hrk antibody detected the Hrk protein (arrow). Rabbit IgG Purified Hu, Ms P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Harakiri / HRK antibody

WB Suggested Anti-HRK Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Thymus Rabbit IgG Purified Bov, Can, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Harakiri / HRK antibody

Harakiri / HRK Rabbit Aff - Purified Hu WB
0.1 mg / €410.00
  Acris Antibodies GmbH

Harakiri / HRK antibody

Western blot analysis of mouse pancreas lysate probed with Rabbit anti Human Hrk (AP05593PU-N) at 2.5(A) and 5(B) µg/ml. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Harakiri / HRK antibody

Western blot analysis of mouse pancreas lysate probed with Rabbit anti Human Hrk (AP05593PU-N) at 2.5(A) and 5(B) µg/ml. Rabbit IgG Purified Hu, Ms, Rt WB
50 µg / €270.00
  Acris Antibodies GmbH

Harakiri / HRK Control Peptide

Harakiri / HRK
50 µg / €160.00
  Acris Antibodies GmbH

Harakiri / HRK antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the HRK polyclonal antibody ( Cat # PAB2444 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu, Ms E, P
0.4 ml / €390.00
  Abnova Taiwan Corp.

Harakiri / HRK antibody

Harakiri / HRK Rabbit Hu WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

Harakiri / HRK antibody

Western blot analysis of HRK in mouse pancreas tissue lysate with HRK polyclonal antibody ( Cat # PAB12959 ) at ( A ) 2.5 and ( B ) 5 µg/ml. Rabbit Hu, Ms WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Harakiri / HRK antibody

Human Thymus; WB Suggested Anti-HRK Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Thymus; HRK antibody - N-terminal region (ARP46364_P050) in Human Thymus cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Harakiri / HRK antibody

Harakiri / HRK Mouse IgG RB0959-RB0960 Purified Hu, Ms E, F, IP, P, WB
0.1 mg / €530.00
  Novus Biologicals Inc.

Harakiri / HRK antibody

Harakiri / HRK Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Harakiri / HRK antibody

Western Blot: Hrk Antibody [NBP1-76414] - Analysis of Hrk in mouse pancreas tissue lysate with Hrk antibody at (A) 2.5 and (B) 5 u/mL._x000d_ Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

HRK overexpression lysate

HRK overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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