HBEGF antibody

Principal name

HBEGF antibody

Alternative names for HBEGF antibody

DTR, DTS, HEGFL, Proheparin-binding EGF-like growth factor

SwissProt ID

Q01580 (Pig), Q06175 (Rat), Q06186 (Mouse), Q99075 (Human)

Gene ID

1839 (HBEGF)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Neutralisation (NEUT)

Background of HBEGF antibody

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a 22kDa O-glycosylated protein that is a potent mitogen and chemoattractant for vascular smooth muscle cells, fibroblasts and epithelial cells but not endothelial cells. The natural protein has an apparent molecular mass of 19-23 kDa and exists in multiple forms as a result of heterogeneous O-glycosylation and/or Nterminal truncation. HB-EGF is synthesized as a membrane-anchored precursor(proHB-EGF) that is proteolytically cleaved to release the soluble mature growth factor. The two forms are active as juxtacrine and paracrine/autocrine growth factors respectively.HB-EGF activates two EGF receptor subtypes, HER1/ErbB1 and HER4 and binds to heparan sulfate proteoglycan.

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rahman, F.B., et al. Lab. Invest. 90(7):1033-1048(2010)
Hamaoka, M., et al. J. Biochem. 148(1):55-69(2010)
Smirnova, I.S., et al. Tsitologiia 52(5):357-363(2010)
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HBEGF (Center) antibody

Western blot analysis of HBEGF Antibody (Center) Cat.-No AP52008PU-N in K562 cell line lysates (35ug/lane).This demonstrates the HBEGF antibody detected the HBEGF protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HBEGF

HBEGF Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 50 µg / €199.00

Special Price: 50 µg / €139.00

  OriGene Technologies, Inc.

HBEGF (63-148, His-tag)

HBEGF Human Purified > 85 % by SDS - PAGE E. coli
0.25 mg / €730.00
  Acris Antibodies GmbH

HBEGF (63-148, His-tag)

HBEGF Human Purified > 85 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

HBEGF

HBEGF Human in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

HBEGF

HBEGF Human in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

HBEGF

HBEGF Human
50 µg / €330.00
  Abnova Taiwan Corp.

ELISA Kits

Catalog No.    

Human HBEGF ELISA Kit

Human HBEGF ELISA Kit  
96 Tests / €460.00
  Boster Immunoleader

Human HBEGF ELISA Kit

Representative Standard Curve  
96 Tests / €450.00
  Cohesion Biosciences Ltd.

Lysates

Catalog No.    

HBEGF overexpression lysate

HBEGF overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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