HBP1 antibody

Principal name

HBP1 antibody

Alternative names for HBP1 antibody

HMG box-containing protein 1, HMG box transcription factor 1, High mobility group box transcription factor 1

SwissProt ID

O60381 (Human), Q2KJ34 (Bovin), Q62661 (Rat), Q8R316 (Mouse)

Gene ID

26959 (HBP1), 826959 (CYP71A19)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), African clawed frog, Ze (Zebrafish), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), ChIP assay (ChIP), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P)

Background of HBP1 antibody

The HMG-box protein-1 (HBP1) is a member of the HMG family of transcription factors, which are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, that mediates DNA binding. HBP1 binds to the tumor suppressor proteins Rb and p130 and initiates cell cycle arrest. Terminal cell differentiation requires this initial cell cycle arrest followed by the coordinated expression of genes defined as tissue-specifc markers. Along with initiating the commitment to cell differentiation, the continued activity of HBP1 abrogates the expression of tissue-specific genes by associating with the MyoD proteins. In muscle cell differentiation, the MyoD family of transcription factors, which include Myf5, MyoD and myogenein, induce the expression of these cell-type specific proteins and contribute to the development of cell phenotypes. The progression of terminal differentiation is, therefore, dependent on both a decrease in HBP1 activity and the corresponding activation of MyoD-induced gene transcription.

General readings

Paulson,K.E., (2007) Cancer Res. 67 (13), 6136-6145

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HBP1 antibody

WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HBP1 antibody

Hum. Adult Placenta; Host: Rabbit. Target Name: CHAD . Sample Tissue: Human Adult Placenta . Antibody Dilution: 1.0ug/ml.; HBP1 antibody - middle region (ARP32559_P050) in Hum. Adult Placenta cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

HBP1 antibody

Western blot analysis of extracts from COS-7 cells, using HBP1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HBP1 antibody

WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HBP1 antibody

WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Hela cell lysate. HBP1 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

HBP1 antibody

Western blot analysis on A549 cell lysate using HBP1 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HBP1 antibody

Immunohistochemistry (IHC) analyzes of HBP1 antibody (Cat.-No.: AP06640PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

HBP1 antibody

HBP1 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

HBP1 pSer402 antibody

Western blot analysis of extracts from A549 cells treated with PMA 125ng/ml 30', using HBP1 (Phospho-Ser402) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

HBP1 pSer402 antibody

Western blot analysis of extracts from A549 cells treated with PMA 125ng/ml 30', using HBP1 (Phospho-Ser402) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

HBP1 antibody

HBP1 Rabbit Aff - Purified Hu E, P
50 µg / €205.00
  Assay Biotech

HBP1 antibody

HBP1 Rabbit Aff - Purified Hu E, P
0.1 mg / €310.00
  Assay Biotech

HBP1 antibody

Western blot analysis of extracts from COS7 cells, using HBP1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

HBP1 antibody

Western blot analysis of extracts from COS7 cells, using HBP1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

HBP1 antibody

Human Jurkat; WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Jurkat cell lysate; HBP1 antibody - N-terminal region (ARP38976_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

HBP1 antibody

Human HeLa; WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Hela cell lysate. HBP1 is supported by BioGPS gene expression data to be expressed in HeLa.; HBP1 antibody - middle region (ARP38977_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

HBP1 pSer402 antibody

Western blot analysis of HBP1 (pS402) expression in HEK293T PMA-treated (A); mouse spleen (B); rat spleen (C) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Rt WB
30 µl / €210.00
  Cohesion Biosciences Ltd.

HBP1 pSer402 antibody

Western blot analysis of HBP1 (pS402) expression in HEK293T PMA-treated (A); mouse spleen (B); rat spleen (C) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Rt WB
0.1 ml / €330.00
  Cohesion Biosciences Ltd.

HBP1 pSer402 antibody

Western blot analysis of HBP1 (pS402) expression in HEK293T PMA-treated (A); mouse spleen (B); rat spleen (C) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Rt WB
0.2 ml / €530.00
  Cohesion Biosciences Ltd.

HBP1 antibody

Immunohistochemical analysis of HBP1 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

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