HBP1 antibody

Principal name

HBP1 antibody

Alternative names for HBP1 antibody

HMG box-containing protein 1, HMG box transcription factor 1, High mobility group box transcription factor 1

SwissProt ID

O60381 (Human), Q2KJ34 (Bovin), Q62661 (Rat), Q8R316 (Mouse)

Gene ID

26959 (HBP1), 73389 (Hbp1)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), African clawed frog, Ze (Zebrafish), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of HBP1 antibody

The HMG-box protein-1 (HBP1) is a member of the HMG family of transcription factors, which are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, that mediates DNA binding. HBP1 binds to the tumor suppressor proteins Rb and p130 and initiates cell cycle arrest. Terminal cell differentiation requires this initial cell cycle arrest followed by the coordinated expression of genes defined as tissue-specifc markers. Along with initiating the commitment to cell differentiation, the continued activity of HBP1 abrogates the expression of tissue-specific genes by associating with the MyoD proteins. In muscle cell differentiation, the MyoD family of transcription factors, which include Myf5, MyoD and myogenein, induce the expression of these cell-type specific proteins and contribute to the development of cell phenotypes. The progression of terminal differentiation is, therefore, dependent on both a decrease in HBP1 activity and the corresponding activation of MyoD-induced gene transcription.

General readings

Paulson,K.E., (2007) Cancer Res. 67 (13), 6136-6145

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HBP1 antibody

  Rabbit Polyclonal Anti-HBP1 Antibody  
WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HBP1 antibody

  Rabbit polyclonal anti-HBP1 antibody  
Western blot analysis of extracts from COS-7 cells, using HBP1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HBP1 antibody

  Rabbit Polyclonal Anti-HBP1 Antibody  
WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HBP1 antibody

  Rabbit Polyclonal Anti-HBP1 Antibody  
WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Hela cell lysate. HBP1 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

HBP1 antibody

  Rabbit Polyclonal Anti-HBP1 Antibody  
Western blot analysis on A549 cell lysate using HBP1 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HBP1 antibody

Immunohistochemistry (IHC) analyzes of HBP1 antibody (Cat.-No.: AP06640PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

HBP1 pSer402 antibody

Western blot analysis of extracts from A549 cells treated with PMA 125ng/ml 30', using HBP1 (Phospho-Ser402) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

HBP1 pSer402 antibody

Western blot analysis of extracts from A549 cells treated with PMA 125ng/ml 30', using HBP1 (Phospho-Ser402) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

HBP1 antibody

HBP1 Rabbit Aff - Purified Hu E, P
50 µg / €230.00
  Assay Biotech

HBP1 antibody

HBP1 Rabbit Aff - Purified Hu E, P
0.1 mg / €330.00
  Assay Biotech

HBP1 antibody

Western blot analysis of extracts from COS7 cells, using HBP1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

HBP1 antibody

Western blot analysis of extracts from COS7 cells, using HBP1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

HBP1 - human gene knockout kit via CRISPR

HBP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

HBP1 - human gene knockout kit via CRISPR

HBP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

HBP1 - human gene knockout kit via CRISPR

HBP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

HBP1 - human gene knockout kit via CRISPR

HBP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hbp1 - mouse gene knockout kit via CRISPR

Hbp1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Hbp1 - mouse gene knockout kit via CRISPR

Hbp1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hbp1 - mouse gene knockout kit via CRISPR

Hbp1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hbp1 - mouse gene knockout kit via CRISPR

Hbp1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

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