HCCS / CCHL antibody

Principal name

HCCS / CCHL antibody

Alternative names for HCCS / CCHL antibody

Cytochrome c-type heme lyase, Holocytochrome c-type synthase

SwissProt ID

A5PJG7 (Bovin), P53701 (Human), P53702 (Mouse), Q5F339 (Chick)

Gene ID

3052 (HCCS)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of HCCS / CCHL antibody

HCCS is a 79 amino acid protein that may act as a tumor suppressor, promoting the apoptosis of cancer cells. Expressed in leukocytes, lung, spleen, liver, heart, kidney, muscle and uterine cervix, HCCS-1 is down-regulated in cervical cancers. The gene encoding HCCS-1 maps to human chromosome 15q25.1. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and comprises about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

General readings

Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Wimplinger, I., et al. Mol. Vis. 13, 1475-1482 (2007)
Wimplinger, I., et al. Am. J. Hum. Genet. 79(5):878-889(2006)
Nakashima-Kamimura, N., et al. J. Cell. Sci. 118 (PT 22), 5357-5367 (2005)
Prakash, S.K., et al. Hum. Mol. Genet. 11(25):3237-3248(2002)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HCCS / CCHL antibody

Western blot analysis of extracts from HeLa cells, HepG2 cells and COLO cells, using Cytochrome c-type Heme Lyase antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HCCS / CCHL antibody

WB Suggested Anti-HCCS Antibody; Titration: 1.0 ug/ml; Positive Control: HepG2 Whole Cell Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HCCS / CCHL (Center) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded colon carcinoma reacted with HCCS / CCHL Antibody (Center) Cat.-No AP52011PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HCCS / CCHL antibody

HCCS / CCHL Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

HCCS / CCHL antibody

HCCS MaxPab polyclonal antibody. Western Blot analysis of HCCS expression in human placenta. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HCCS / CCHL antibody

Western Blot analysis of HCCS expression in transfected 293T cell line (H00003052-T02) by HCCS MaxPab polyclonal antibody.

Lane 1: HCCS transfected lysate(30.60 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

HCCS / CCHL antibody

HCCS / CCHL Mouse IgG2a 3C7 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

HCCS / CCHL antibody

HCCS / CCHL Mouse IgG1 2CYZ-702 Hu, Ms, Rt IP, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

HCCS / CCHL antibody

Immunohistochemistry analysis of paraffin-embedded human tonsil tissue, using Cytochrome c-type Heme Lyase Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

HCCS / CCHL antibody

Immunohistochemistry analysis of paraffin-embedded human tonsil tissue, using Cytochrome c-type Heme Lyase Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

HCCS / CCHL (C-term) antibody

Human HepG2; WB Suggested Anti-HCCS Antibody. . Titration: 1.0 ug/ml. . Positive Control: HepG2 Whole Cell; HCCS antibody - C-terminal region (ARP61090_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

HCCS / CCHL (N-term) antibody

Human U937; WB Suggested Anti-HCCS Antibody. . Titration: 1.0 ug/ml. . Positive Control: U937 Whole Cell; HCCS antibody - N-terminal region (ARP61091_P050) in Human U937 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

HCCS / CCHL antibody

Immunohistochemical analysis of HCCS staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Mky, Ms, Rt ICC/IF, IP, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

HCCS / CCHL antibody

Immunohistochemical analysis of HCCS staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Mky, Ms, Rt ICC/IF, IP, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

HCCS / CCHL antibody

Immunohistochemical analysis of HCCS staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Mky, Ms, Rt ICC/IF, IP, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

HCCS / CCHL antibody

HCCS / CCHL Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

HCCS / CCHL antibody

HCCS / CCHL Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

HCCS / CCHL antibody

Immunohistochemistry-Paraffin: HCCS Antibody [NBP1-86577] - Immunohistochemical staining of human parathyroid gland shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HCCS / CCHL

HCCS / CCHL Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

HCCS / CCHL

HCCS / CCHL Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

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