HCN1 / BCNG1 antibody
Principal name
HCN1 / BCNG1 antibody
Alternative names for HCN1 / BCNG1 antibody
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, Brain cyclic nucleotide-gated channel 1
Ncbi ID
Available reactivities
Available hosts
Available applications
Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P)
Background of HCN1 / BCNG1 antibody
Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligand- gated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
Specifically, hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, play a crucial role in the regulatons of cell excitability. Importantly, they contribute to spontaneous rhythmic activity in both the heart and brain (3).








Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
---|---|---|---|---|---|---|---|
TA322238 | HCN1 / BCNG1 antibody |
||||||
Anti-HCN1 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
TA326543 | HCN1 / BCNG1 antibody |
||||||
Mouse Monoclonal Anti-HCN1 Antibody | |||||||
![]() |
Mouse | IgG1 | S70-28 | Purified | Hu, Ms, Rt | C, IP, P, WB |
0.1 mg /
€410.00
|
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
TA327462 | HCN1 / BCNG1 antibody |
||||||
HCN1 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
TA328955 | HCN1 / BCNG1 antibody |
||||||
Rabbit polyclonal Anti-HCN1 | |||||||
![]() |
Rabbit | Purified | Hu, Ms, Rt | WB |
0.2 ml /
€585.00
|
||
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
73-110 | HCN1 / BCNG1 antibody |
||||||
![]() |
Mouse | IgG1 | N70/28 | Supernatant | Hu, Ms, Rt | C, IP, WB |
5 ml /
€490.00
|
Antibodies Incorporated | |||||||
![]() |
|||||||
75-110 | HCN1 / BCNG1 antibody |
||||||
![]() |
Mouse | IgG1 | N70/28 | Purified | Hu, Ms, Rt | C, IP, WB |
0.1 ml /
€570.00
|
Antibodies Incorporated | |||||||
![]() |
|||||||
AP55189SU-N | HCN1 / BCNG1 antibody |
||||||
![]() |
Rabbit | Serum | Hu | C, E, WB |
0.2 ml /
€430.00
|
||
OriGene Technologies GmbH |
Human Lenti ORF Particles
Catalog No. | ||
---|---|---|
RC220956L2V | Lenti ORF particles, HCN1 (mGFP-tagged)-Human hyperpolarization activated cyclic nucleotide-gated potassium channel 1 (HCN1), 200 uL, >10^7 TU/mL |
|
![]() |
200 µl /
€1,980.00
|
|
OriGene Technologies, Inc. | ||
RC220956L1V | Lenti ORF particles, HCN1 (Myc-DDK-tagged)-Human hyperpolarization activated cyclic nucleotide-gated potassium channel 1 (HCN1), 200 uL, >10^7 TU/mL |
|
![]() |
200 µl /
€1,780.00
|
|
OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
Catalog No. | ||
---|---|---|
MR221659L2V | Lenti ORF particles, Hcn1 (GFP-tagged) - Mouse hyperpolarization-activated, cyclic nucleotide-gated K+ 1 (Hcn1), 200 uL, >10^7 TU/mL |
|
![]() |
200 µl /
€1,760.00
|
|
OriGene Technologies, Inc. | ||
MR221659L1V | Lenti ORF particles, Hcn1 (Myc-DDK-tagged) - Mouse hyperpolarization-activated, cyclic nucleotide-gated K+ 1 (Hcn1), 200 uL, >10^7 TU/mL |
|
![]() |
200 µl /
€1,580.00
|
|
OriGene Technologies, Inc. | ||