HCN3 antibody

Principal name

HCN3 antibody

Alternative names for HCN3 antibody

KIAA1535, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3

SwissProt ID

O88705 (Mouse), Q9JKA8 (Rat), Q9P1Z3 (Human)

Gene ID

57657 (HCN3), 15168 (Hcn3), 114245

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rat, Rabbit, Mouse, Goat

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of HCN3 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligand- gated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
Specifically, hyperpolarization-activated cation channels of the HCN gene family contribute to spontaneous rhythmic activity in both the heart and brain (3).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HCN3 antibody

AP23226PU-N HCN3 antibody staining of Rat Kidney lysate at 1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

HCN3 antibody

(0.01ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Purified Bov, Can, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HCN3 antibody

Western blot analysis of HCN3 in rat brain membrane lysates using a 1:1000 dilution of the antibody Mouse IgG1 S141-28 Purified Ms, Rt C, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HCN3 antibody

Western blot analysis of HCN3 in rat brain lysate: 1. Anti-HCN3 antibody , (1:200). 2. Anti-HCN3 antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

HCN3 antibody

WB Suggested Anti-HCN3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: COLO205 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HCN3 antibody

Adult rat brain membrane immunoblot Mouse IgG1 N141/28 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

HCN3 antibody

Adult rat brain membrane immunoblot Mouse IgG1 N141/28 Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

HCN3 antibody

HCN3 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

HCN3 antibody

HCN3 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

HCN3 antibody

Human COLO205; WB Suggested Anti-HCN3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: COLO205 cell lysate; HCN3 antibody - middle region (ARP35310_P050) in Human COLO205 cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

HCN3 antibody

HCN3 Rat IgG1 TLL6C5 Ascites Hu, Ms, Rt P
0.1 ml / €400.00
  Novus Biologicals Inc.

HCN3 antibody

HCN3 Goat Aff - Purified Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

HCN3 antibody

Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402] Immunohistochemical staining of human duodenum shows strong cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

13 Item(s)

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