HCV NS3 antibody

Principal name

HCV NS3 antibody

Alternative names for HCV NS3 antibody

Hepatitis C Virus Serine proteiase NS3

Available reactivities

Hu (Human), Vi (Virus)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Frozen Sections (C), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of HCV NS3 antibody

HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins including NS3, and several non-structural proteins necessary for viral replication.
The NS3 part of the polyprotein displays three enzymatic activities: serine protease, NTPase and RNA helicase.
The NS3 serine proteinase (NS3P) is a non-structural hepatitis C protein responsible for proteolytic processing of other non-structural proteins; because of this, it is also the most extensively studied protein of the Hepatitis C genome. It is responsible for proteolytic processing of the entire downstream region of the HC polyprotein, catalyzing cleavage at the NS3/NS4a, NS4a/NS4b, NS4b/NS5a, and NS5a/NS5b sites to release the mature NS3, NS4a, NS4b, NS5a, and NS5b proteins.For proper function, NS3 requires NS4a as a cofactor, but, interestingly enough, NS3 also cleaves the NS4a protein. The molecular weight of the monomer NS3P is 70 kDa.

General readings

Hahn JA., et al. (2007) J Infect Dis. 195(11):1556-9.
Caruntu FA., et al. (2006) J Gastrointestin Live Dis. 15(3):249-56.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HCV NS3 antibody

HCV NS3 Mouse IgG1 B179M Purified E, ICC/IF, WB
1 mg / €810.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 B182M Purified E, ICC/IF, WB
1 mg / €810.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 70-13 Aff - Purified Hu E, WB
0.5 mg / €430.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 1-5 Aff - Purified Hu E, WB
0.5 mg / €430.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 12-15 Aff - Purified Hu E, WB
0.5 mg / €430.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 5-11 Aff - Purified Hu E, WB
0.5 mg / €430.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 24-8 Azide Free Hu E, WB
0.5 mg / €430.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 20-8 Aff - Purified Hu E, WB
0.5 mg / €430.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 113 Aff - Purified Hu E, WB
0.5 mg / €450.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 281 Aff - Purified Hu E, WB
0.5 mg / €450.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 5 Aff - Purified Hu E, WB
0.5 mg / €430.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 328 Aff - Purified Hu E, WB
0.5 mg / €450.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 251 Aff - Purified Hu E, WB
0.5 mg / €450.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 242 Aff - Purified Hu E, WB
0.5 mg / €430.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 133 Aff - Purified Hu E, WB
0.5 mg / €430.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG2a 806 Aff - Purified Hu E, WB
0.5 mg / €450.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Goat Purified E, WB
1 ml / €440.00
  Acris Antibodies GmbH

HCV NS3 antibody

HCV NS3 Mouse IgG1 1244/3B5 Purified E, WB
0.2 mg / €440.00
  Acris Antibodies GmbH

HCV NS3 (1252-1477) antibody

HCV NS3 Mouse IgG1 781 Purified E
1 mg / €1,730.00
  Acris Antibodies GmbH

HCV NS3 (1252-1477) antibody

HCV NS3 Mouse IgG2 981 Purified C, E, WB
1 mg / €1,730.00
  Acris Antibodies GmbH

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