HDAC10 antibody

Principal name

HDAC10 antibody

Alternative names for HDAC10 antibody

Histone deacetylase 10, HD10

SwissProt ID

Q569C4 (Rat), Q6P3E7 (Mouse), Q969S8 (Human)

Gene ID

83933 (HDAC10), 918

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Luminex (LMNX)

Background of HDAC10 antibody

Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the eta-amino groups of lysines located near the amino termini of core histone proteins (2). Eight members of HDAC family have been identified in the past several years (3,4). These HDAC family members are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8, each of which contains a deacetylase domain exhibiting from 45 to 93% identity in amino acid sequence. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold larger than those of the class I members, and the deacetylase domains are present within the C-terminal regions, except that HDAC-6 contains two copies of the domain, one within each of the N-terminal and C-terminal regions. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns (4). These results suggested that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo. HDAC8 interacts with PEPB2-MYH11, a fusion protein consisting of the 165 N-terminal residues of CBF-beta (PEPB2) with the tail region of MYH11 produced by the inversion Inv(16)(p13q22), a translocation associated with acute myeloid leukemia of M4EO subtype. The PEPB2-MYH1 fusion protein also interacts with RUNX1, a well known transcriptional regulator, suggesting that the interaction with HDAC8 may participate to convert RUNX1 into a constitutive transcriptional repressor.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HDAC10 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-HDAC10 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500725, Dilution 1:50) Mouse IgG2a OTI6G5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC10 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-HDAC10 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500751, Dilution 1:50) Mouse IgG1 OTI8G5 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC10 antibody

Immunohistochemical staining of paraffin-embedded pancreas tissue within the normal limits using anti-HDAC10mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500752, Dilution 1:50) Mouse IgG2a OTI4D4 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC10 antibody

Immunohistochemical staining of paraffin-embedded pancreas tissue within the normal limits using anti-HDAC10mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500756, Dilution 1:50) Mouse IgG1 OTI7C3 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC10 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of bladder tissue using anti-HDAC10mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500759, Dilution 1:50) Mouse IgG1 OTI3c2 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC10 antibody

Immunohistochemical staining of paraffin-embedded colon tissue within the normal limits using anti-HDAC10mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500760, Dilution 1:50) Mouse IgG2a OTI2H6 Purified Hu F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

HDAC10 antibody

Immunohistochemical staining of paraffin-embedded pancreas tissue within the normal limits using anti-HDAC10mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500787, Dilution 1:50) Mouse IgG2a OTI5E2 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC10 (N-term) antibody

Western blot analysis of anti-HDAC10 Pab (Cat. TA300100) in A375 cell line lysates. HDAC10(arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HDAC10 antibody

Western blot analysis of extracts from COS7 cells, using HDAC10 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HDAC10 antibody

Western blot analysis on COS7 cell lysate using HDAC10 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HDAC10 antibody

Western Blot: HDAC10 Antibody [TA336684] - WB analysis of HDAC10 in HeLa cells with TA336684 at a dilution of 1:250. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HDAC10 antibody

Western Blot: HDAC10 Antibody [TA336886] - analysis of HDAC-10 in HeLa cells using this antibody. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HDAC10 antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-HDAC10mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500750, Dilution 1:50) Mouse IgG2a OTI9B5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC10 antibody

Immunohistochemical staining of paraffin-embedded pancreas tissue within the normal limits using anti-HDAC10mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500753, Dilution 1:50) Mouse IgG2a OTI5A1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC10 antibody

Immunohistochemical staining of paraffin-embedded pancreas tissue within the normal limits using anti-HDAC10mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500754, Dilution 1:50) Mouse IgG2b OTI6D4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC10 antibody

Anti-HDAC10 mouse monoclonal antibody (TA500755) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HDAC10(RC218536). Mouse IgG1 OTI1B1 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC10 antibody

HDAC10 ELISA with 5A1 Capture (TA600429) and 6G5 Detection (TA700429) Antibodies. Substrate used: Recombinant Human HDAC10 (TP318536) Mouse IgG1 OTI5A1 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

HDAC10 antibody

HDAC10 ELISA with 6G5 Capture (TA600430) and 5A1 Detection (TA700430) Antibodies. Substrate used: Recombinant Human HDAC10 (TP318536) Mouse IgG1 OTI6G5 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

HDAC10 antibody

HDAC10 ELISA with 9B5 Capture (TA600431) and 4D4 Detection (TA700431) Antibodies. Substrate used: Recombinant Human HDAC10 (TP318536) Mouse IgG1 OTI9B5 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

HDAC10 antibody

HDAC10 ELISA with 5A1 Capture (TA600429) and 6G5 Detection (TA700429) Antibodies. Substrate used: Recombinant Human HDAC10 (TP318536) Mouse IgG1 OTI6G5 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

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