HDAC11 antibody

Principal name

HDAC11 antibody

Alternative names for HDAC11 antibody

Histone deacetylase 11, HD11

SwissProt ID

Q91WA3 (Mouse), Q96DB2 (Human)

Gene ID

79885 (HDAC11)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Dros (Drosophila), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of HDAC11 antibody

Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the eta-amino groups of lysines located near the amino termini of core histone proteins (1). Eight members of HDAC family have been identified in the past several years (2,3). These HDAC family members are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8, each of which contains a deacetylase domain exhibiting from 45 to 93% identity in amino acid sequence. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about twofold larger than those of the class I members, and the deacetylase domains are present within the C-terminal regions, except that HDAC-6 contains two copies of the domain, one within each of the N-terminal and C-terminal regions. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns (3). Recently, a new member of this family, HDAC11, has been cloned by Gao et al (4). HDAC11 transcripts were limited to kidney, heart, brain, skeletal muscle, and testis. These results suggested that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo.

General readings

Janssen, C., et al. J. Neuropathol. Exp. Neurol. 69(6):573-581(2010)
Glozak, M.A., et al. J. Biol. Chem. 284(17):11446-11453(2009)
Georgopoulos, K. Nat. Immunol. 10(1):13-14(2009)
Villagra, A., et al. Nat. Immunol. 10(1):92-100(2009)
Fournel, M., et al. Mol. Cancer Ther. 7(4):759-768(2008)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HDAC11 antibody

Western Blot: HDAC11 Antibody [TA336345] - Western blot analysis of HDAC11 using HDAC11 antibody. Brain lysate from (A) human, (B) mouse and © rat brain probed with HDAC11 antibody at 2 ug/ml. Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HDAC11 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HDAC11 (RC201919, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HDAC11. Mouse IgG1 OTI7H10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC11 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HDAC11 (RC201919, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HDAC11. Mouse IgG1 OTI7A7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC11 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HDAC11 (RC201919, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HDAC11. Mouse IgG1 OTI2G5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC11 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HDAC11 (RC201919, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HDAC11. Mouse IgG1 OTI7D2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC11 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HDAC11 (RC201919, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HDAC11. Mouse IgG1 OTI1D5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HDAC11 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HDAC11 (C-term) antibody

(LEFT) Purified rabbit anti-HDAC11 antibody (C-term) (Cat.#AP11143PU-N) was used in immunohistochemistry on Breast Carcinoma. (RIGHT) Formalin-fixed and paraffin-embedded human testicle tumor tissue reacted with HDAC11 antibody (C-term) (Cat.#AP11143PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HDAC11 (Center) antibody

Western blot analysis of HDAC11 Antibody (Center) Cat.-No AP52023PU-N in mouse testis tissue lysates (35ug/lane). This demonstrates the HDAC11 antibody detected the HDAC11 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HDAC11 antibody

Western Blot analysis of HDAC11 expression in transfected 293T cell line (H00079885-T01) by HDAC11 MaxPab polyclonal antibody.

Lane 1: HDAC11 transfected lysate(38.17 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HDAC11 antibody

Immunoprecipitation of HDAC11 transfected lysate using anti-HDAC11 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with HDAC11 MaxPab mouse polyclonal antibody (B01) (H00079885-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

HDAC11 antibody

Immunofluorescence of monoclonal antibody to HDAC11 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG1 1C2-2G5 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

HDAC11 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the HDAC11 polyclonal antibody ( Cat # PAB2342 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

HDAC11 antibody

Purified rabbit HDAC11 polyclonal antibody ( Cat # PAB2343 ) was used in immunohistochemistry on breast carcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

HDAC11 antibody

Western blot analysis of HDAC11 polyclonal antibody ( Cat # PAB8749 ) in lysates from Jurkat cells ( Lane 1 ) and mouse small intestine ( Lane 2 ) . Rabbit Hu, Ms, Rt WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

HDAC11 antibody

Hum. Adult Placenta; Host:Rabbit. Target Name:HDAC11. Sample Tissue:Human Adult Placenta. Antibody Dilution: 1.0ug/ml.; HDAC11 antibody - middle region (ARP42789_P050) in Hum. Adult Placenta cells using Western Blot Rabbit Aff - Purified Bov, Dros, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

HDAC11 antibody

Human Small Intestine; WB Suggested Anti-HDAC11 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Small Intestine; HDAC11 antibody - middle region (ARP42790_P050) in Human Small Intestine cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

HDAC11 antibody

Western Blot: HDAC11 Antibody [NBP1-44267] - Mouse brain homogenate samples were loaded on to a 10% Prep-gel Tris-Glycine polyacrylamide gels and blotted onto PVDF membranes. The membranes was probed with 0.2ug/ml of affinity purified NBP1-44267 antibody in 5% non-fat dry milk TBST over night at 4 C. The membrane was then further probed with goat anti rabbit HRP at 1:40, 000 and developed using a standard chemiluminescence method. A major band at 39 kDa and a minor band at 37 kDa are observed. Both bands are blocked when the immunizing peptide is included in the incubation (data not shown). Rabbit Aff - Purified Hu E, WB
0.1 mg / €510.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HDAC11 (transcript variant 2)

HDAC11 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

HDAC11

HDAC11 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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