Heat shock protein beta-6 / HSPB6 antibody

Principal name

Heat shock protein beta-6 / HSPB6 antibody

Alternative names for Heat shock protein beta-6 / HSPB6 antibody

HSP20, Heat shock 20 kDa-like protein p20

SwissProt ID

O14558 (Human), P97541 (Rat), Q148F8 (Bovin), Q5EBG6 (Mouse)

Gene ID

126393 (HSPB6)

Available reactivities

Hu (Human), Rt (Rat), Bov (Bovine), Can (Canine), Fe (Feline), GP (Guinea Pig), Ms (Mouse), Por (Porcine), Rb (Rabbit), Sh (Sheep), Fi (Fish), Chk (Chicken), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of Heat shock protein beta-6 / HSPB6 antibody

Hsp20 is a small heat shock protein related to Hsp25, Hsp27 and may form different hetercomplexes with these proteins. The specific physiological function of Hsp20 is not yet known. It is distributed ubiquitously in tissues, but is found in higher levels in skeletal, smooth and heart muscle. Under normal conditions, Hsp20 is diffusely distributed in the cytosol, but under heat stress conditions, it translocates to the nucleus. Unlike other heat shock proteins the amount of Hsp20 does not increase after heat shock. The Hsp20 was demonstrated to constitute up to 1.3% of the total cellular protein in vertebrate tissues, especially in muscle, and its expression is related to muscle contraction, specifically in slow-twitch muscle. Hsp20 may form different heterocomplexes with other Hsp's, such as alpha-crystalline and Hsp25. Phosphorylated form of Hsp20 is proposed to interact with monomeric actin whereas dephosphorylated form binds polymeric actin filaments. In normal conditions Hsp20 is diffusely disturbed in cytosol but under the heat stress it undergoes translocation to membrane fraction.

General readings

General / background references:Tessier DJ et al. The small heat shock protein (HSP) 20 is dynamically associated with the actin cross-linking protein actinin. J Surg Res 111:152-7 (2003). PubMed PMID: 12842460
Kozawa O et al. HSP20, low-molecular-weight heat shock-related protein, acts extracellularly as a regulator of platelet functions: a novel defense mechanism. Life Sci 72:113-24 (2002). PubMed PMID: 12417245
Beall A et al. The small heat shock-related protein, HSP20, is phosphorylated on serine 16 during cyclic nucleotide-dependent relaxation. J Biol Chem 274:11344-51 (1999). PubMed PMID: 10196226
Brophy CM et al. Phosphorylation of the small heat shock-related protein, HSP20, in vascular smooth muscles is associated with changes in the macromolecular associations of HSP20. J Biol Chem 274:6324-9 (1999). PubMed PMID: 10037721
Beall AC et al. Cyclic nucleotide-dependent vasorelaxation is associated with the phosphorylation of a small heat shock-related protein. J Biol Chem 272:11283-7 (1997). PubMed PMID: 9111032
Kato K et al. Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin. J Biol Chem 269:15302-9 (1994). PubMed PMID: 8195168

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Heat shock protein beta-6 / HSPB6 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using HSP20 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Heat shock protein beta-6 / HSPB6 antibody

Heat shock protein beta-6 / HSPB6 Rabbit IgG Purified Hu, Ms, Rt P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Heat shock protein beta-6 / HSPB6 antibody

Heat shock protein beta-6 / HSPB6 Mouse IgG2a HSP20-11 Purified Hu, Rt E, ICC/IF, P, WB
1 mg / €540.00
  Acris Antibodies GmbH

Heat shock protein beta-6 / HSPB6 antibody

HSPB6 MaxPab polyclonal antibody. Western Blot analysis of HSPB6 expression in human liver. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Heat shock protein beta-6 / HSPB6 antibody

Heat shock protein beta-6 / HSPB6 Mouse IgG2a 6A4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Heat shock protein beta-6 / HSPB6 antibody

Immunofluorescent staining for HSPB6 antigen using HSPB6 monoclonal antibody, clone HSP20-11 ( green-HSP20, red-actin ) with MDBK cell line (bovine kidney). Mouse IgG2a HSP20-11 Hu E, ICC/IF, WB
0.2 mg / €1,080.00
  Abnova Taiwan Corp.

Heat shock protein beta-6 / HSPB6 pSer16 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using HSP20 (Phospho-Ser16) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P
50 µg / €205.00
  Assay Biotech

Heat shock protein beta-6 / HSPB6 pSer16 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using HSP20 (Phospho-Ser16) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P
0.1 mg / €310.00
  Assay Biotech

Heat shock protein beta-6 / HSPB6 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HSP20 (Ab-16) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €205.00
  Assay Biotech

Heat shock protein beta-6 / HSPB6 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HSP20 (Ab-16) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €310.00
  Assay Biotech

Heat shock protein beta-6 / HSPB6 antibody

Human HepG2; WB Suggested Anti-HSPB6 Antibody Titration: 1.25ug/ml. Positive Control: HepG2 cell lysate; HSPB6 antibody - middle region (ARP48436_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

Heat shock protein beta-6 / HSPB6 antibody

Heat shock protein beta-6 / HSPB6 Mouse IgG2a HSP20-11 Purified Hu, Rt E, ICC/IF, WB
0.2 mg / €580.00
  HyTest Ltd.

Heat shock protein beta-6 / HSPB6 antibody

Western Blot analysis of rat heart lysate, probed with [NB120-13491] Rabbit IgG Aff - Purified Bov, Can, Fi, Hu, Ms, Rt WB
50 µg / €380.00
  Novus Biologicals Inc.

Heat shock protein beta-6 / HSPB6 antibody

Western Blot: Hsp20 Antibody [NBP1-55523] - This Anti-HSPB6 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1.25ug/ml. Rabbit Purified Hu WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Heat shock protein beta-6 / HSPB6 antibody

Heat shock protein beta-6 / HSPB6 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €360.00
  Novus Biologicals Inc.

Heat shock protein beta-6 / HSPB6 antibody

Heat shock protein beta-6 / HSPB6 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Heat shock protein beta-6 / HSPB6

Heat shock protein beta-6 / HSPB6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Heat shock protein beta-6 / HSPB6 (1-160, His-tag)

Heat shock protein beta-6 / HSPB6 Human Purified > 95 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

Heat shock protein beta-6 / HSPB6 (1-160, His-tag)

Heat shock protein beta-6 / HSPB6 Human Purified > 95 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Heat shock protein beta-6 / HSPB6

Heat shock protein beta-6 / HSPB6 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

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