Heme oxygenase 2 (HMOX2) antibody

Principal name

Heme oxygenase 2 (HMOX2) antibody

Alternative names for Heme oxygenase 2 (HMOX2) antibody

HO2, HO-2

SwissProt ID

O70252 (Mouse), P23711 (Rat), P30519 (Human), P43242 (Rabit)

Gene ID

3163 (HMOX2), 15369 (Hmox2), 79239

Available reactivities

Hst (Hamster), Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat), Bov (Bovine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F)

Background of Heme oxygenase 2 (HMOX2) antibody

Heme oxygenase (HO) is a microsomal enzyme involved in cellular response to oxidative stress. HO oxidatively cleaves the heme ring at the alpha methene bridge to form carbon monoxide and biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.
Two heme oxygenase isozymes, termed HO 1 and HO 2, have been identified so far. At the amino acid level, HO 1 and HO 2 are 42% homologous. However, each isozyme is evolutionary highly conserved. HO 1 is the inducible form of the enzyme and is therefore also referred to as stress protein Hsp32. Expression of HO 1 can be induced by a variety of stimuli such as heme, metals, hormones, UV radiation and sulfhydryl depleting agents. In contrast, HO 2 is the constituitive form of the enzyme. It is not inducible by exogeneous stimuli and HO 2 is the most prevalent form in most tissues, except the spleen where HO 1 levels are predominant under normal conditions.

General readings

Sha L, Farrugia G, Harmsen WS, Szurszewski JH. Membrane potential gradient is carbon monoxide-dependent in mouse and human small intestine. American journal of physiology. Gastrointestinal and liver physiology 2007 Aug 293 (2): G438-45. PMID: 17510199

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Heme oxygenase 2 (HMOX2) antibody

  HMOX2 (Heme oxygenase 2) mouse monoclonal antibody, clone OTI4H8 (formerly 4H8)  
Anti-HMOX2 mouse monoclonal antibody (TA503925) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HMOX2(RC201777). Mouse IgG2b OTI4H8 Purified Hu F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Heme oxygenase 2 (HMOX2) antibody

  HMOX2 (Heme oxygenase 2) mouse monoclonal antibody, clone OTI1C2 (formerly 1C2)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-HMOX2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503813) Mouse IgG1 OTI1C2 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Heme oxygenase 2 (HMOX2) antibody

  HMOX2 (Heme oxygenase 2) mouse monoclonal antibody, clone OTI1D10 (formerly 1D10)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-HMOX2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503819) Mouse IgG2a OTI1D10 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Heme oxygenase 2 (HMOX2) antibody

  HMOX2 (Heme oxygenase 2) mouse monoclonal antibody, clone OTI1B4 (formerly 1B4)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-HMOX2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503822) Mouse IgG1 OTI1B4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Heme oxygenase 2 (HMOX2) antibody

  HMOX2 (Heme oxygenase 2) mouse monoclonal antibody, clone OTI1H10 (formerly 1H10)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-HMOX2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503823) Mouse IgG2b OTI1H10 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Heme oxygenase 2 (HMOX2) antibody

  Goat Anti-HMOX2 Antibody  
TA305779 (0.3ug/ml) staining of K562 cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Heme oxygenase 2 (HMOX2) antibody

  Anti-HMOX2 Rabbit Polyclonal Antibody  
Predicted band size: 36 kDa . Positive control: HepG2 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 30 ug Primary antibody: 1/550 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 15 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Heme oxygenase 2 (HMOX2) antibody

  Anti-HMOX2 Rabbit Polyclonal Antibody  
Predicted band size: 36 kDa . Positive control: HepG2 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 30 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 15 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Heme oxygenase 2 (HMOX2) antibody

  Rabbit Polyclonal Anti-HO 2 Antibody  
Western blot analysis of HO 2 expression in K562 cell lysate Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Heme oxygenase 2 (HMOX2) antibody

  HMOX2 (Heme oxygenase 2) mouse monoclonal antibody, clone OTI4B2 (formerly 4B2)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HMOX2 (RC201777, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HMOX2. Mouse IgG1 OTI4B2 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Heme oxygenase 2 (HMOX2) antibody

  HMOX2 (Heme oxygenase 2) mouse monoclonal antibody, clone OTI4E10 (formerly 4E10)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HMOX2 (RC201777, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HMOX2. Mouse IgG1 OTI4E10 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Heme oxygenase 2 (HMOX2) antibody

  HMOX2 (Heme oxygenase 2) mouse monoclonal antibody, clone OTI4H6 (formerly 4H6)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HMOX2 (RC201777, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HMOX2. Mouse IgG1 OTI4H6 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Heme oxygenase 2 (HMOX2) antibody

Western blot analysis of HO-2 expression in rat microsomes. Rabbit Aff - Purified Hst, Hu, Mky, Ms, Rt C, IP, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

HMOX2 - human gene knockout kit via CRISPR

HMOX2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

HMOX2 - human gene knockout kit via CRISPR

HMOX2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

HMOX2 - human gene knockout kit via CRISPR

HMOX2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

HMOX2 - human gene knockout kit via CRISPR

HMOX2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Heme oxygenase 2 (HMOX2) (transcript variant 3)

  Recombinant protein of human heme oxygenase (decycling) 2 (HMOX2), transcript variant 3  
Heme oxygenase 2 (HMOX2) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Heme oxygenase 2 (HMOX2) (transcript variant 2)

  Purified recombinant protein of Homo sapiens heme oxygenase (decycling) 2 (HMOX2), transcript variant 2  
Heme oxygenase 2 (HMOX2) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Heme oxygenase 2 (HMOX2) (transcript variant 4)

  Purified recombinant protein of Homo sapiens heme oxygenase (decycling) 2 (HMOX2), transcript variant 4  
Heme oxygenase 2 (HMOX2) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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