Hemoglobin alpha antibody

Principal name

Hemoglobin alpha antibody

Alternative names for Hemoglobin alpha antibody

HBA1, Alpha-globin, Hemoglobin alpha chain

SwissProt ID

P69905 (Human)

Gene ID

3039 (HBA1), 3040 (HBA2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P)

Background of Hemoglobin alpha antibody

Hemoglobin alpha chain belongs to the globin family and is involved in oxygen transport from the lung to the various peripheral tissues. Hemoglobin A is comprised of two alpha chains and two beta chains, whereas hemoglobin A2 is comprised of two alpha chains and two delta chains. Immunohistochemical localization of hemoglobin is excellent as an erythroid marker for the detection of immature, dysplastic, and megaloblastic erythroid cells in myeloproliferative disorders, such as erythroleukemia. In contrast, myeloid cells, lymphoid cells, plasma cells, histiocytes and megakaryocytes are negative for hemoglobin alpha antibody. Anti-hemoglobin alpha, combined with CD34, CD117, CD68, and MPO can be helpful in distinguishing between reactive extramedullary hematopoiesis and that seen in neoplastic myeloid disorders in spleen.
Anti-hemoglobin alpha is limited to expression by erythoid precursors in bone marrow, thus is of assistance in calculating percentages of erythroid precursors.

General readings

Sessa, R., et al. Am. J. Hematol. 85(2):143-144(2010)
Sharma, V., et al. Hematology 14(5):297-300(2009)
Waye, J.S., et al. Hemoglobin 33(6):519-522(2009)
Roy, P., et al. Hemoglobin 33(6):486-491(2009)
Joly, P., et al. Hemoglobin 33(3):196-205(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Hemoglobin alpha antibody

  Rabbit Monoclonal anti-Hemoglobin Alpha Chain Antibody  
Western Blot analysis of heart lysate with anti-hemoglobin alpha chain antibody. Rabbit IgG SP212 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Hemoglobin alpha antibody

  Rabbit Monoclonal Hemoglobin A Antibody  
Immunohistochemistry staining of Paraffin Bone Marrow, placenta tissue by Hemoglobin A antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic) Rabbit IgG EPR3608 Purified Hu P
1 ml / €680.00
  OriGene Technologies, Inc.

Hemoglobin alpha antibody

Formalin-Fixed, Paraffin-Embedded Human bone marrow stained with Hemaglobin A antibody Cat.-No. AM10092SU-N using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining of erythroid precursors. Rabbit IgG EPR3608 Supernatant Hu, Ms, Rt P, WB
1 ml / €430.00
  Acris Antibodies GmbH

Hemoglobin alpha (Center) antibody

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with HBA2 Antibody (Center) Cat.-No AP52006PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Aff - Purified Hu, Ms F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Hemoglobin alpha antibody

Hemoglobin alpha Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Hemoglobin alpha antibody

Hemoglobin alpha Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Hemoglobin alpha antibody

Hemoglobin alpha Mouse IgG2a 4F9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CRISPR

Catalog No. Species Donor Vector  

HBA1 - human gene knockout kit via CRISPR

HBA1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

HBA1 - human gene knockout kit via CRISPR

HBA1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

HBA1 - human gene knockout kit via CRISPR

HBA1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

HBA1 - human gene knockout kit via CRISPR

HBA1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

HBA2 - human gene knockout kit via CRISPR

HBA2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

HBA2 - human gene knockout kit via CRISPR

HBA2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Hemoglobin alpha

  Recombinant protein of human hemoglobin, alpha 2 (HBA2)  
Hemoglobin alpha Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Hemoglobin alpha (1-142, His-tag)

Hemoglobin alpha Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Hemoglobin alpha (1-142, His-tag)

Hemoglobin alpha Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Hemoglobin alpha

Hemoglobin alpha Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Hemoglobin alpha

Hemoglobin alpha Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Hemoglobin alpha

Hemoglobin alpha Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Hemoglobin alpha

Hemoglobin alpha Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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