Paraffin Sections (P), Western blot / Immunoblot (WB)
Background of Heparanase-2 / HPA2 antibody
Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.
Immunohistochemical analysis of paraffin-embedded Uterus, using HPA2(GTX100589) antibody(10 µg/ml).
Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with Heparanase-2 / HPA2 Antibody (C-term) Cat.-No AP52095PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining.