Hepatocyte growth factor / HGF antibody

Principal name

Hepatocyte growth factor / HGF antibody

Alternative names for Hepatocyte growth factor / HGF antibody

Scatter factor, Hepatopoeitin-A, HPTA

SwissProt ID

P14210 (Human), P17945 (Rat), Q08048 (Mouse), Q76BS1 (Bovin), Q867B7 (Canfa), Q9BH09 (Felca), Q9BYM0 (Human)

Gene ID

3082 (HGF), 15234 (Hgf), 24446

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rb (Rabbit), Rt (Rat), Chk (Chicken), Eq (Equine), Por (Porcine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E), ELISA (detection) (E(detection))

Background of Hepatocyte growth factor / HGF antibody

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity.Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.

General readings

Wu X, Chen X, et al. (2013). Cancer Lett. 10;335(1):128-35.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Hepatocyte growth factor / HGF antibody

  HGF mouse monoclonal antibody, clone OTI1D2 (formerly 1D2)  
Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-HGF mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA807184)(1:150) Mouse IgG2a OTI1D2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Hepatocyte growth factor / HGF antibody

  HGF mouse monoclonal antibody, clone OTI2F3 (formerly 2F3)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-HGF mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA807186) Mouse IgG1 OTI2F3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Hepatocyte growth factor / HGF antibody

  HGF mouse monoclonal antibody, clone OTI3F2 (formerly 3F2)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-HGF mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA807223) Mouse IgG1 OTI3F2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Hepatocyte growth factor / HGF antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between HGF and MET. Mahlavu cells were stained with anti-HGF rabbit purified polyclonal 1:1200 and anti-MET mouse purified polyclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Hepatocyte growth factor / HGF antibody

  Anti-HGF Mouse Monoclonal (7-2) Antibody  
Anti-HGF antibody IHC of human brain, cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Mouse IgG2a 7-2 Purified Hu, Ms P, WB
50 µg / €345.00
  OriGene Technologies, Inc.

Hepatocyte growth factor / HGF antibody

  Rabbit anti-HGF Polyclonal Antibody  
Western blot analysis of extracts from HepG2 cells, treated with PMA (125ng/ml, 30mins), using CD227/MUC1 (Phospho-Tyr1229) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Hepatocyte growth factor / HGF antibody

  Rabbit Polyclonal Anti-HGF Antibody  
WB Suggested Anti-HGF Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 293T cell lysate;There is BioGPS gene expression data showing that HGF is expressed in HEK293T Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Hepatocyte growth factor / HGF antibody

  Rabbit Polyclonal Anti-HGF Antibody  
WB Suggested Anti-HGF Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Eq, GP, Hu, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Hepatocyte growth factor / HGF antibody

  Rabbit Polyclonal Anti-HGF Antibody  
WB Suggested Anti-HGF Antibody Titration: 0.2-1 ug/ml; Positive Control: ACHN cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Hepatocyte growth factor / HGF antibody

  Rabbit Polyclonal Anti-HGF Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (HGF Antibody) at dilution 1/65, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Hepatocyte growth factor / HGF antibody

  Mouse monoclonal Anti-HGF/SF Clone SBF5 C1.7  
Hepatocyte growth factor / HGF Mouse IgG1 SBF5 C1.7 Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Hepatocyte growth factor / HGF antibody

  Mouse monoclonal Anti-HGF/SF Clone EGH2 4C12.1  
Hepatocyte growth factor / HGF Mouse IgG1 EGH2 4C12.1 Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Hepatocyte growth factor / HGF antibody

  HGF mouse monoclonal antibody, clone OTI1C6 (formerly 1C6)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HGF (RC215593, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HGF.(1:2000) Mouse IgG2b OTI1C6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Hepatocyte growth factor / HGF antibody

  HGF mouse monoclonal antibody, clone OTI1E5 (formerly 1E5)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-HGF mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA807224)(1:150) Mouse IgG1 OTI1E5 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Hepatocyte growth factor / HGF (C-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with HGF antibody (C-term) (AP11675PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Hepatocyte growth factor / HGF (521-554) antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu E, F, P, WB
0.2 ml / €470.00
  Acris Antibodies GmbH

Hepatocyte growth factor / HGF antibody

Hepatocyte growth factor / HGF Rabbit Purified Hu E, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

Hepatocyte growth factor / HGF antibody

Hepatocyte growth factor / HGF Rabbit Aff - Purified Hu E, WB
50 µg / €280.00
  Acris Antibodies GmbH

Hepatocyte growth factor / HGF antibody

Hepatocyte growth factor / HGF Rabbit Purified Hu E, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

Hepatocyte growth factor / HGF antibody

Hepatocyte growth factor / HGF Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

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